All undergraduate students have the requirement of completing a graduation project as part of their graduation. Therefore, it is usual that every year a significant number of students have to submit an original project.

The purpose of the graduation projects is to provide students with an opportunity to progress in the strengthening of knowledge and skills acquired throughout their years in the educational system.

These graduation projects can be considered as pilot projects on topics related to real problems. In this sense, could be interesting develop comprehensive laboratory projects which require addressing tasks from the different scopes of Chemistry.

Taking into account these standpoints, the re-design old experiments adding new point of view, the computerized data treatment, the construction and verification of new automatized small instrumentation, etc., could be a stimulating starting point for the kind of mentioned projects.

The aim of this Special Issue is to offer laboratory experiences that can be used as basis of graduation projects. Nonetheless, the contributions are open to develop just a part of the complete graduation project.

A number of challenges continue to affect the teaching of chemistry at all levels of schooling. Some of the challenges include barriers such as, time to do experiments during class time, studying chemistry online and at the distance as well as the unavailability and/or expensive chemistry apparatus. The proposal intends to look at the overview of current trends, research and practices in the use of online tools to teach scientific enquiry in chemistry. The question is can scientific enquiry be taught to chemistry learners/students using online tools, if so, how best can teachers use online tools to teach chemistry.