Advances in vehicular technology and demands for safer transportation present more challenges now than ever. In the USA alone, accidents accounted for more than $300 billion in damaged property, more than 2 million nonfatal injuries, and almost 50,00 deaths annually. There has been shared consensus among researchers and governments that those figures can be brought down by applying modern safety applications. Applications like Cooperative Intersection Collision Avoidance Systems (CICASs), safe lane change, and autonomous auto-drive have captured the attention of researchers and provide solid platform to evaluate and compare different performance enhancement approaches.

The special issue is focused on Mathematical Methods in Reliability and Safety Engineering. The submission is drastically extended as it is an independent of the original research papers. The articles concerning new research on reliability theory with particular emphasis on safety problems are invited. Authors are encouraged to submit high quality papers describing the results of theoretical and experimental research.