Basic Sciences of Medicine

Basic Sciences of Medicine is a peer reviewed international basic medical sciences journal, which is aimed to promote research and information in basic medical sciences. It can improve health, health care and health education, internationally by elevating the quality of medical care, disease prevention, and research.

Sadia Mohsin

Post-doctoral Fellow, Temple University Philadelphia, USA

Research Areas

Stem cell biology, molecular biology, aging, heart disease, regenerative biology, microbiology

Publications: Journals

[1]  Toko H, Hariharan N, Konstandin MH, Ormachea L, McGregor M, Gude NA, Sundararaman B, Joyo E, Joyo AY, Collins B, Din S, Mohsin S, Uchida T, Sussman MA. The Journal of Biology and Chemistry. 2014 Feb 28;289 (9):5348-56.
[2]  Mohsin S, Wu JC, Sussman MA. Predicting the future with stem cells. Circulation. 2014 Jan 14;129(2):136-8.
[3]  Mohsin S, Khan M, Nguyen J, Alkatib M, Siddiqi S, Hariharan N, Wallach K, Monsanto M, Gude N, Dembitsky W, Sussman MA. Rejuvenation of human cardiac progenitor cells with pim-1 kinase. Circulation Research. 2013 Oct 25;113(10):1169-79.
[4]  Khan M, Mohsin S, Toko H, Alkatib M, Nguyen J, Truffa S, Gude N, Chuprun K, Tilley DG, Koch WJ, Sussman MA. Cardiac Progenitor Cells Engineered With βARKct Have Enhanced β-Adrenergic Tolerance. Moecular Therapy. 2014 Jan;22(1):178-85.
[5]  Nasir GA*, Mohsin S*, Khan M, Shams S, Ali G, Khan SN and Riazuddin S. Mesenchymal stem cells and Interleukin-6 attenuate liver fibrosis in mice. Journal of Translational Medicine. 2013 Mar 26;11:78.
[6]  Khan M, Mohsin S, Avitabile D, Siddiqi S, Nguyen J, Wallach K, Quijada P, McGregor M, Gude N, Alvarez R, Tilley DG, Koch WJ, Sussman MA. β-adrenergic regulation of cardiac progenitor cell death versus survival and proliferation. Circulation Research. 2013 Feb 1;112(3):476-86.
[7]  Khan M*, Ali F*, Mohsin S, Akhtar S, Mahmood A, Choudhery MS, Khan SN, Riazuddin S. Preconditioning of mesenchymal stem cells with myogenic medium increases their ability to repair diabetic heart. Stem Cell Research and Therapy. 2013 May 24;4(3):58.
[8]  Mohsin S, Khan M, Toko H, MD, Bailey B, Cottage CT, Wallach K, Nag D, Lee A, Siddiqi S, Lan F, Fischer KM, Gude N, Quijada P, Avitabile D, Truffa S, Collins B, Dembitsky W, Wu JC, Sussman MA. Human cardiac progenitor cells engineered with Pim-1 kinase enhance myocardial repair. Journal of American College of Cardiology 2012; 60(14):1278-87
[9]  Ali G*, Mohsin S*, Khan M, Nasir GA, Shams S, Khan SN, Riazuddin S. Nitric oxide augments mesenchymal stem cell ability to repair liver fibrosis. Journal of Translational Medicine. 2012 Apr 25; 10(1):75.
[10]  Mohsin S*, Siddiqi S*, Collins B, Sussman MA. Empowering adult stem cells for myocardial regeneration. Circulation Research. 2011 Dec; 109(12):1415-28.
[11]  Choudhery MS*, Khan M*, Mahmood R, Mohsin S, Akhtar S, Ali F, Khan SN, Riazuddin S. Mesenchymal stem cells conditioned with glucose depletion augments their ability to repair infracted myocardium. Journal of Cellular and Molecular Medicine 2012 Oct; 16(10):2518-29
[12]  Cheng Z, Völkers M, Din S, Avitabile D, Khan M, Gude N, Mohsin S, Bo T, Truffa S, Alvarez R, Mason M, Fischer KM, Konstandin MH, Zhang XK, Brown JH, Sussman MA. Mitochondrial translocation of Nur77 mediates cardiomyocyte apoptosis. European Heart Journal. 2011 Sep; 32(17):2179-88.
[13]  Khan M, Mohsin S, Khan SN, Riazuddin S. Repair of senescent myocardium by mesenchymal stem cells is dependent on the age of donor mice. Journal of Cellular and Molecular Medicine. 2011 Jul; 15(7):1515-27
[14]   Avitabile D, Bailey B, Cottage CT, Sundararaman B, Joyo A, McGregor M, Gude N, Truffa S, Zarrabi A, Konstandin M, Khan M, Mohsin S, Völkers M, Toko H, Mason M, Cheng Z, Din S, Alvarez R Jr, Fischer K, Sussman MA. Nucleolar stress is an early response to myocardial damage involving nucleolar proteins nucleostemin and nucleophosmin. Proceedings of the National Academy of Sciences U S A. 2011 Apr 12; 108(15):6145-50.
[15]  Khan M*, Akhtar S*, Mohsin S, Khan SN, Riazuddin S. Growth Factor Preconditioning Increases the Function of Diabetes-Impaired Mesenchymal Stem Cells. Stem Cells Development. 2011 Jan; 20(1): 67-75.
[16]  Mohsin S, Shams S, Nasir, GA, Khan M, Awan SJ, Khan SN, Riazuddin S. Enhanced hepatic differentiation of mesenchymal stem cells after pretreatment with injured liver tissue. Differentiation 2011 Jan; 20(1):67-75.
[17]   Yasmeen A, Riazuddin SA, Kaul H, Mohsin S, Khan M, Qazi ZA, Nasir IA, Zafar AU, Khan SN, Husnain T, Akram J, Hejtmancik JF, Riazuddin S. Autosomal recessive congenital cataract in consanguineous Pakistani families is associated with mutations in GALK1. Molecular Vision. 2010 Apr 15; 16:682-8.
[18]  Kaul H, Riazuddin SA, Yasmeen A, Mohsin S, Khan M, Nasir IA, Khan SN, Husnain T, Akram J, Hejtmancik JF, Riazuddin S. A new locus for autosomal recessive congenital cataract identified in a Pakistani family. Molecular Vision. 2010 Feb 16; 16:240-5
[19]  Khan M, Mohsin S, Khan SN, Riazuddin S. Lin-c-kit+ BM-derived stem cells repair Infarcted Heart. Journal of Stem cells and Regenerative. Medecine. 2010 Apr 5;6(1):15-25. eCollection 2010.
[20]  Khan M*, Manzoor S*, Mohsin S, Khan SN, Ahmad FJ. IGF-1 and G-CSF complement each other in BMSCs migration towards infarcted myocardium in a novel in vitro model. Cell Biology International 2009; 33(6): 650-657.

Publications: Conferences/Workshops/Symposiums

[1]  Hariharan N, Joyo AY, Mohsin S, Quijada PJ, Samse KM, Avitabile D, Ormachea L, Bailey B, McGregor MJ, Cottage CT, Joyo EE, Sussman MA. Nucleostemin Antagonizes Senescence of Cardiac Progenitor Cells. Circulation. 2013;128:A16085.
[2]  Mohsin S, Khan M, Alkatib M, Nguyen J, Wallach K, Sussman MA. Pim-1 Modification Reverses Senescent Phenotype Of hCPCs From Patients With Heart Disease. Circulation Research. 2013;113:A135
[3]  Hariharan N, Samse KM, Joyo AY, Avitabile D, Samse KM, Bailey B, Quijada PJ, McGregor M, Mohsin S, Siddiqi S, Sussman MA. Nucleostemin Induced by Pim-1 Kinase Antagonizes Senescence of Cardiac Progenitor Cells. Circulation Research. 2013;113:A326.
[4]  Khan M, Mohsin S, Nguyen J, Alkatib M, Truffa S, Gude N, Koch WJ, Sussman MA. Human Cardiac Progenitor Cells Engineered with {beta}ARK-ct Have Increased Survival and Proliferation. Circulation. 2012;126:A13507.
[5]  Mohsin S, Khan M, Wallach K, Cottage T, Sussman MA. Pim-1 Engineering of Human CPCs Increases Telomere Length from Aged Patients with Heart Failure. Circulation. 2012;126:A13587.
[6]  Mohsin S, Khan M, Wallach K, Cottage T, Mcgregor M, Sussman MA. Pim-1 Engineering of Human CPCs Increases Telomere Length from Aged Patients with Heart Failure. Circulation Research. 2012;111:A62
[7]  Khan M, Mohsin S, Avitabile D, Nguyen J, Gude N, Sussman MA. {beta}-Adrenergic Signaling Promotes Survival and Proliferation of Mouse Cardiac Progenitor Cells Prior to Lineage Commitment. Circulation Research. 2012;111:A65
[8]  Mohsin S, Khan M, Toko H, Bailey B, Siddiqi S, Fischer K, Gude N, Truffa S, Sussman MA. Pim-1 Engineering of Human CPCs Increases Their Ability to Repair the Heart After Myocardial Infarction. Circulation Research. 2011;109:AP002.