Research In Cancer and Tumor

International Journal of Cancer and Tumor is a peer-reviewed international journal which provides a forum for prompt communication of original and innovative research findings that have relevance to understanding the etiology of cancer and to improving the treatment and survival of patients.


Yongping Chen

Editorial Board Member of Research In Cancer and Tumor

Post-doctoral Fellow, Johns Hopkins University, USA

Research Areas

Phage Display-selected Peptides used in Drug Delivery and Molecular Imaging, Nano/Biophotonics, Contrast Agents for OCT and NIR Molecular Imaging, Bioconjugation, Drug Release, Photothermal Therapy

Education

2009.01-presentPostdoctoral fellowBiophotonics lab, Department of Biomedical Engineering, Johns Hopkins University
2007.10-2009.01Research AssociateBiophotonics lab, Department of Biomedical Engineering, University of Washington (move to Johns Hopkins University with Supervisor on 2009, 01)
2002.09-2007.10Ph.D. CandidateSchool of Life Science, University of Science and Technology of China
1994.09-1999.07Medical DegreeClinic Medicine, Anhui Medical University

Experience

1999-2002 Hospital of University of Science and Technology of China

Academic Achievement

2005, Scholarship of Graduate Symposium
2006, Qiu Shi Science and Technology Scholarship
2006, Top 10 Basic Research News in China

Membership

2008-Present, Society of Photographic Instrumentation Engineers (SPIE) member
2010-present, Optical Society of America (OSA) member

Publications: Journals

[1]  Y. P. Chen, Y. Y. Shen, X. Guo, C. S. Zhang, W. J. Yang, M. L. Ma, S. Liu, M. B. Zhang, L. P. Wen, "Transdermal protein delivery by a coadministered peptide identified via phage display. " Nature Biotechnology 2006.24(4):455-460. (R. P. Mark "A peptide chaperone for transdermal drug delivery." Nature Biotechnology 2006.24(4):416-417 (News and Views for Y.P. Chen et al). It was highlighted on Nature Reviews: http://www.nature.com/nrd/journal/v5/n6/full/nrd2068.html
[2]  X. M. Wan, Y. P. Chen, W. R. Xu, W. J. Yang, L. P. Wen. "Identification of nose-to-brain homing peptide through phage display" Peptides 2009.30(2):343-350.
[3]  T. H. Kim, Y. P. Chen, C.W. Mount, W. R. Gombotz, X. D. Li, S. H. Pun " Evaluation of Temperature-Sensitive, Indocyanine Green-Encapsulating Micelles for Noninvasive Near-Infrared Tumor Imaging" Pharmaceutical Research (2010).27:1900-1913
[4]  K. Murari, Y. Y. Zhang, S. P. Li, Y. P. Chen, M. J. Li, X. D. Li. "Compensation free all-fiber-optic two-photon endomicroscopy at 1.55 μm" Optics Letters (2011) 36 (7):1299-1301.
[5]  Q. G. Yang, Q. Zhang, Y. P. Chen, L. Cao, W. Jiang, G. H. Chen " Functional recovery of injured sciatic nerve by intraperitoneal injection of multiwalled carbon nanotubes" Neural Regeneration Research (2011).6(7):505-509
[6]  J. F. Xi, Y. C. Wu, T. H. Kim, Y. P. Chen, D. S. Zheng, L. Huo, M. C. Cobb, S. Z. Pun, J. H. Hwang, X. D. Li. "Endomicroscopy and Biocompatible Fluorescence Nanocomplex for Clinical Translation of High-resolution Optical Molecular Imaging" IEEE 2009. pp 48-51

Publications: Conferences/Workshops/Symposiums

[1]  Y. C. Wu, J. F. Xi, Y. P. Chen, M. J. Cobb, M. J. Li, X. D. Li. "Fiber-Optic Endomicroscopy for Intrinsic Two-photon Fluorescence Imaging of Epithelial cells and Tissues" in Conference on Lasers and Electro-Optics/International Quantum Electronics Conference, OSA Technical Digest (CD) (Optical Society of America, 2009), paper CMCC6.
[2]  Y. P. Chen, T. G. Jabbour , X. D. Li, "Bioconjugated ICG/Dox-Micellar Nanocapsules for Optical Molecular imaging and targeted therapy" in Biomedical Optics, OSA Technical Digest (CD) (Optical Society of America, 2010), paper BTuC6.
[3]  Y. P. Chen, X. D. Li, "Thermo/pH-Responsive and Reversible NIR Fluorescent Probes" in Biomedical Optics, OSA Technical Digest (CD) (Optical Society of America, 2010), paper JMA105.
[4]  L. Huo, Y. P. Chen, J. F. Xi, K. Hsu, X. D. Li. "Gold Nanocages for Spectroscopic OCT imaging with a Swept Source at 1060 nm" in Biomedical Optics, OSA Technical Digest (CD) (Optical Society of America, 2010), paper BSuD10.
[5]  L. Huo, J. F. Xi, Y. P. Chen, X. D. Li. "Forward-Viewing Endoscope of Appropriate Scanning Speed for 3-D OCT imaging" in Biomedical Optics, OSA Technical Digest (CD) (Optical Society of America, 2010), paper BTuD16.
[6]  J. F. Xi, Y. Y. Zhang, L. Huo, Y. P. Chen, T. G. Jabbour, M. J. Li and Xingde Li, "Emerging fiber optic endomicroscopy technologies towards noninvasive real-time visualization of histology in situ" Proc. SPIE 7653, 765307 (2010); doi:10.1117/12.867758
[7]  J. F. Xi, K. Murari, Y. Y. Zhang, L. Y. P. Chen, J. S. Li and Xingde Li, "OCT Endomicroscopy and Functional Integration with Two-photon Fluorescence Imaging" in Bio-Optics: Design and Application, OSA Technical Digest (CD) (Optical Society of America, 2011), paper BWA5.
[8]  Y. P. Chen, T. G. Jabbour , X. D. Li, "Functional Fluorescent Nanocapsules for Molecular Imaging and Potential Targeted Therapy " in CLEO:2011 - Laser Applications to Photonic Applications, OSA Technical Digest (CD) (Optical Society of America, 2011), paper JME1.
[9]  Y.Y. Zhang, K. Murari, J.F. Xi, Y. P. Chen, M. Arkin, S. Kakkad, M. Mahendroo, K. Luby-Phelps, S.P. Li, Z. Bhujwalla, K. Glunde, M. J. Li, and X. D. Li, " Fiber-optic Two-photon Fluorescence and Second Harmonic Generation Endomicroscopy" in Quantum Electronics and Laser Science Conference, OSA Technical Digest (CD) (Optical Society of America, 2011), paper JThA1.

Publications: Books/Book Chapters

[1]  C. W. Mount, S. H. Pun, Y. P. Chen, and X. D. Li, "Micelles as delivery vehicles for near-infrared (NIR) dyes," in Handbook of NIR Dyes: Science and Applications, Gabor Patonay, Ed., Pan Stanford Publishing (2011, in press).