International Journal of Internal Medicine

International Journal of Internal Medicine is aimed to publish high-quality internationally competitive peer-reviewed original medical research, both laboratory and clinical, relating to the study and research of human disease. Papers will be considered from all areas of medical practice and science. It is an international journal dedicated to the latest advancement of internal medicine.

Wenzhen Xiao

Post-doctoral Fellow, Icahn school of Medicine at Mount Sina, USA

Research Areas

Kidney fibrosis and Chronic kidney disease

Publications: Journals

[1]  Fan Y, Xiao W, Li Z, Li X, Chuang PY, Jim B, Zhang W, Wei C, Wang N, Jia W, Xiong H, Lee K, and He JC. RTN1 mediates progression of kidney disease by inducing ER stress. Nat Commun 6: 7841, 2015. (Co-first author, contributed equally to the study.) (IF: 11.470)
[2]  Xiao W, Fan Y, Wang N, et al. Knockdown of RTN1A attenuates ER stress and kidney injury in albumin overload-induced nephropathy. American Journal of Physiology-Renal Physiology, 2016: ajprenal. 00485.2015. (IF: 3.248)
[3]  Xiao W, Gui D, Chen T. Effects of Astragaloside IV Protect Against Podocyte Lesion Exposed to High Glucose. Chinese Journal of Integrated Traditional and Western Nephrology, 2013, 5: 008. (IF: 1.217)
[4]  Fan Y, Li X, Xiao W, et al. BAMBI elimination enhances alternative TGF-β signaling and glomerular dysfunction in diabetic mice. Diabetes, 2015, 64(6): 2220-2233. (IF: 8.095)
[5]  Fan Y, Wei C, Xiao W, et al. Temporal profile of the renal transcriptome of HIV-1 transgenic mice during disease progression. PloS one, 2014, 9(3): e93019. (IF: 3.234)
[6]  Gui D, Huang J, Liu W, Guo Y, Xiao W, et al. Astragaloside IV prevents acute kidney injury in two rodent models by inhibiting oxidative stress and apoptosis pathways. Apoptosis, 2013, 18(4): 409-422. (IF: 3.685)
[7]  Gui D, Huang J, Guo Y, J Chen, Chen Y, Xiao W, et al. Astragaloside IV ameliorates renal injury in streptozotocin-induced diabetic rats through inhibiting NF-κB-mediated inflammatory genes expression. Cytokine, 2013, 61(3): 970-977. (IF: 2.664)
[8]  Chen T, Zheng L Y, Xiao W, et al. Emodin Ameliorates High Glucose Induced-Podocyte Epithelial-Mesenchymal Transition In-Vitro and In-Vivo. Cellular Physiology and Biochemistry, 2015, 35(4): 1425-1436. (IF: 2.875)

Publications: Conferences/Workshops/Symposiums

[1]  Ying Fan, Wenzhen Xiao, Peter Y. Chuang, Kim Lee, Niansong Wang, John C. He. Role of RTN1-A in Mediating Tubular Cell Injury Induced by Albumin Overload. (Poster presentation at American Society of Nephrology Kidney Week 2015, San Diego, CA.)
[2]  Ying Fan, Chengguo Wei, Wenzhen Xiao, Niansong Wang, Peter Y. Chuang, John C. He. Temporal Profile of the Renal Transcriptome of HIV-1 Transgenic Mice during Disease Progression. (Poster Presentation at American Society of Nephrology Kidney Week 2014, Philadelphia, Pennsylvania.)