American Journal of Chemistry

American Journal of Chemistry is a peer-reviewed chemistry journal. It is aimed to publish all the latest and outstanding research articles, reviews and letters in all areas of Chemistry.

Adel Amer

Editorial Board Member of American Journal of Chemistry

Professor, Alexandria University, Egypt

Research Areas

Organic Chemistry


1983Ph.D.University of Cincinnati, U.S.A. (Advisor: Prof. Hans Zimmer)
1978M.Sc.Alexandria University, Egypt (Advisors: Prof. E.S.H. El Ashry and Prof. M.M. Abdel Rahman)
1975B.Sc.Alexandria University


1994-pesentProfessor, Department of Chemistry, Faculty of Science, University of Alexandria
2006-2007Visiting Scientist, Department of Chemistry, Central Washington University
2005-2006Visiting Professor, Department of Chemistry, Northen Arizona University
2004-2005Visiting Professor, Department of Chemistry, Faculty of Science, United Arab Emirates University
2002-2003Adjunct Professor and Research Scholar, Department of Chemistry, Northen Arizona University
1994-2000Professorof Chemistry, Faculty of Science, United Arab Emirates University
1995, 1997-1998Visiting Scholar , Department of Chemistry, University of Cincinnati
1988-1994Assoc.Professor Department of Chemistry, Faculty of Science, University of Alexandria

Academic Achievement

Alexandria University Award for research (1991-1992)
NTNF fellowship award (1989-1990) from the Royal Norwegian Council for Scientific and Industrial Research


American Chemical Society
Sigma Xi (member)
The New York Academy of Sciences
The American Association for The Advancement of Science
The International Society for Heterocyclic Chemistry
Syndicate of Scientific Professions (Egypt)
Egyptian Chemical Society
Egyptian Association for Heterocyclic Chemistry

Publications: Conferences/Workshops/Symposiums/Journals/Books

[1]  Transformation of the Hydrazones of 6-Chloro-3-(L-threo-2, 3, 4-trihydroxy-1-oxobutyl)-2-Quinoxalinone into otherHeterocyclicCompounds;E. S. H. El Ashry, M. M.A. A. Abdel Rahman, M. A. Nassr and Adel Amer, Carbohydr. Res. 67, 403 (1978).
[2]  Reaction of Dehydro-D-Erythorbic Acid andits Aryl Analogs with ortho-Diamine; E. S. H. El Ashry, M. M. A. AbdelRahman, N. Rashedand Adel Amer, Carbohydr. Res. 67, 423 (1978).
[3]  A New Synthesis of Pyridazinone from Carbohydrate Precursors, Using the Wittig Reagent;E. S. H. El Ashry, M. M. A. Abdel Rahman, Y. El Kilany and Adel Amer, Carbohydr. Res. 87, C5 (1981).
[4]  Semicarbazones Derived from Dehydro-L-Ascorbic Acid;E. S. H. El Ashry, Y. El Kilany, Adel Amer and H. Zimmer, Carbohydr. Res. 94, C16 (1981).
[5]  The Reaction of 1-Hydrazinophthalazine with Phthaladehydic Acid; Occurrence of Ring-Chain Tautomers; Adel AmerandH.Zimmer, J. Heterocycl. Chem. 18, 1625 (1981).
[6]  Remark to the Publication "Synthesis of Some Substituted Pyrazolo-1-phthalazine Derivatives with Possible Hypertensive Action, by R. Soliman and H. Mokhtar"; H. Zimmer, Adel Amer and L. Baldwin, Pharmazie37, 451 (1982).
[7]  Reaction of Alkyl-and Dialkylaminotriphenylphosphonium Halides and Halogens and Interhalogen Compounds;Formation of Alkylaminotriphenyl-phosphonium Polyhalides; H. Zimmer, M. J. Jaywant, Adel Amer and B. Ault, Z. Naturforsch. 38b, 103 (1983).
[8]  Reaction ofketo-substituted--Butyrolactones with Diamines; Adel Amer, H. Zimmer and M. Ventura, J. Heterocycl. Chem. 20, 359 (1983).
[9]  A Novel Ring Closure to Furo[2, 3-b]quinoxaline; Adel Amer, H. Zimmer and M. Ventura, Z. Naturforsch. 38b, 992 (1983).
[10]  Ring Closure Reaction Involving 1-Hydrazinophthalazine; Reaction with 1, 2, 4-Tricarbonyl and 1, 3-Dicarbonyl Compounds; Adel Amer and H. Zimmer, J. Heterocycl. Chem. 20, 1231 (1983).
[11]  Polymerization of 3-Methyl-2, 5-Dibromothiophene Utilizingn-Butyl Lithium and Copper(II) chloride; Adel Amer, H. Zimmer, K. J. Mulligan, H. B. Mark, Jr., S. Pons, and J. F. McAleer, J. Polm. Sci. Polym. Lett. 22, 77 (1984).
[12]  The Electrochemical Behaviour in Aqueous Media of Conducting Polymers; The Methanol Soluble Fraction Obtained on the Cu(II) catalyzed Polymerization of 2, 5-Dibromo-3-Methylthiophene; A. Czerwinski, H. Zimmer, C. Van Pham, Adel Amer, J. R. Schrader and H. B. Mark, Jr., Analytical Letters 18 (A6), 673 (1985).
[13]  The Effect of Water and Transition Metal Ion Doping on the Conductivity ofthe Poly(3-substituted Thiophene-2, 5-diyls; A. Czerwinski, H. Zimmer, Adel Amer, C. Van Pham, S. Pons and H. B. Mark, Jr, J. Chem. Soc. Chem. Commun. 1158 (1985).
[14]  Reduction of 4-Aroyl-3-Hydroxy-2(5H)-furanones;H. Zimmer, M. Ventura, M. Manning, Adel Amer and A. El Massry, J. Heterocycl. Chem. 23, 199 (1986).
[15]  Development of a Successful Gas Chromatographic Method of Analyzing o-Aminobenzenesulfonic Acids Via Their Sulfonyl Chlorides; Adel Amer, E. G. Alley and C. U. Pittman, Jr., J. Chromatogr. 362, 413 (1986).
[16]  The Electrochemical Behaviour in Aqueous Media of Conducting Polymers II:InsolubleFractionObtainedintheCu(II)catalyzed Polymerization of (2, 5-Dibromo-3-Group IV substituted)Thiophenes; A. Czerwinski, D. Cunningham, Adel Amer, J. R. Schrader, H. Zimmer, C. V. Pham, H. B. Mark, Jr. and S. Pons, J. Electrochem. Soc. 134, 1158 (1987).
[17]  NovelSynthesis of Pyridazinones, Preparation of 3-[1-Aryl-6(1H)-Pyridazinon-3-yl]-2(1H)Quinoxalinones; E. S. H. El Ashry, Y. El Kilany and Adel Amer, Heterocycles 26, 2101 (1987).
[18]  Access tothe 2, 3-Dihydropyridazin-3-one andas-Triazino[3, 4-a]phthalazine Ring Systems from Pyruvic Acids; E. S. H. El Ashry, Adel Amer, Abdel Moneim El Massry, M. M. A. Abdel Rahmanand G. Labib, J. Heterocycl. Chem. 24, 63 (1987).
[19]  SomeNovel Observations onthe Reaction of 1-Hydrazinophthalazine with Polycarbonyl Compounds; H. Zimmer and Adel Amer, Heterocycls26, 1177 (1987).
[20]  Pyrazoles Derived from Dihydralazine; Adel Amer, N. Rashed, M. M. A. Abdel Rahman and H. Zimmer, Heterocycles26, 1277 (1987).
[21]  Factors Influencing the Pathway of Reactions of 1-Hydrazinophthalazine with Di-and Tricarbonyl Compounds; Adel Amer, K. Wesiz and H. Zimmer, Heterocycles26, 1853 (1987).
[22]  Complexing Ability of Some-Lactone Derivatives.Thermal Magnetic and Spectral Studies on Cobalt(II), Nickel(II) and Copper(II) Complexes and their Base Adducts; A. El-Dissouky, A. Fahmy and Adel Amer, Inorg. Chem. Acta133, 311 (1987).
[23]  On The Synthesis of 4-Alkoxy-2(5H)Furanones; H. Zimmer, Adel Amer, C. V. Pham and D. G. Schmidt, J. Org. Chem.53, 3368 (1988).
[24]  Reaction of 1-Hydrazinophthalazine with Phenyl(3-phenyloxiran-2-yl)methanone: A Reinvestigation; Adel Amer, A. M. El Massry, S. El Sadany and H. Zimmer, J. Chem. Research(s)298 (1988).
[25]  Studies of Some Hindered 2, 2'-Bithienyls and 3, 3'-Bridged 2, 2'-Bithienyls with Special Reference to their UV Spectra and Oxidation Potentials; Adel Amer, A. Burkhart, A. Nkansah, R. Shabana, A. Galal, H. B. Mark, Jr. and H. Zimmer, Phosphorus and Sulfur42, 63 (1989).
[26]  Synthesis of New s-Triazolo[4, 3-b]pyridazines; A. M. El Massry and Adel Amer, Heterocycles29, 1907 (1989).
[27]  A New Synthesis of 3, 3'-Dinitrodiphenyl Sulfone (DNDPS); Adel Amer, A. El Massry and C. U. Pittman, Jr., Chemica Scripta29, 351 (1989).
[28]  Conductivity Monitoring by an Amperometric Detector with a Cu(II) Containing Poly(3-Methylthiophene) Electrode; Z. L. Xue, A. Karagzler, O. Y. Ataman, A. Galal, Adel Amer, R. Shabana, H. Zimmer and H. B. Mark, Jr., Electroanalysis2, 1 (1990).
[29]  A Facile Synthesis of Novel Triazoloquinoxalinones; N. Rashed, A. M. El Massry, E. S. H. El Ashry, Adel Amer and H. Zimmer, J. Heterocycl. Chem.27, 691 (1990).
[30]  ANovelSynthesisof the2, 1, 4-Benzoxathiazine-1, 1-dioxideRing System; Adel Amer, J. Harrison, A. Merijanian and C. U. Pittman, Jr., J. Chem. Research(s)122 (1990).
[31]  On The Synthesis and Mass-Spectroscopical Identification of Certain Polyhalogenated AceticAcids;H.Zimmer, Adel Amer and M. Rahi, Analytical Letters23, 735 (1990).
[32]  A Convenient Synthesis of Long-Chain 3-n-Alkylthiophenes and 3-n-Alkylfuranes; R. Shabana, Adel Amer, H.B.Mark, Jr.and H.Zimmer, Phosphorus and Sulfur53, 299 (1990).
[33]  ANovelReductiveDehalogenation usingPotassium Hydroxide/Polyethylene Glycol (400)/Xylene mixtures, A. M. El Massry, Adel Amer and C. U. Pittman, Jr., Synth. Commun.20, 1091 (1990).
[34]  A NovelOxidativeSkeleton Rearrangement of Caffeine System; H. Zimmer, Adel Amer, D. Ho, K. Koch, C. Schumacher and R. C. Wingfield, J. Org. Chem.55, 4988 (1990).
[35]  Structureof theReactionProductsfromDehydroascorbicAcid Analogues, o-Phenylenediamine and Arylhydrazines.X-rayMolecular Structure of 3-[L-threo-2, 3, 4-Triacetoxy-1-(Phenylhydrazono)butyl]quinoxalin-2(1H)-one Hemihydrate, Adel Amer, N. Rashed, A. M. El Massry, L. Fathi, E. S. El Ashry and D. Ho, J. Chem. Soc. Perkin Trans. I2513 (1990).
[36]  Substituted-Lactones:Reactions ofArylmethylenefurandiones with Nucleophiles.A Novel Approach to the Cyclolignan Lactone Skeleton;Adel Amer, D. Ho, K. Rumpel, R. Schenkel and Hans Zimmer, J. Org. Chem.56, 5210 (1991).
[37]  Substituted-Lactones:On The Structural Elucidation of The Reaction Products from 4-Aroyl-3-Hydroxy-2(5H)-Furanones and 1, 2-Diamines, H. Zimmer, Adel Amer, D. Ho and R. Palmer-Sungail, J. Heterocycl. Chem.28, 1501 (1991).
[38]  Electrochromism and Electrochemical Characterization of Soluble Poly[3-Alkylheteroarylenes], A. Galal, A. Ersin Karagzler, R. Shabana, Adel Amer, H. Zimmer and H. B. Mark, Jr., Sol. Energy Mater.25, 339 (1992).
[39]  Synthesis andStructuralElucidation ofthe Acetylation Reaction's Product(s) of the 2(1H)-Quinoxalinones Derived from L-Ascorbic Acid.X-ray Molecular Structureof 3-(N-acetyl-2-naphthylhydrazono)-2, 3-dihydro-2-acetoxyfuro[2, 3-b]Quinoxaline, Adel Amer and D. Ho, Z. Naturforsch.47b, 861 (1992).
[40]  Structural Elucidation of theHitherto2, 3-Dihydro-1, 2, 3, 5-benzothiatriazepine-1, 1-dioxide Ring System, C. U. Pittman, Jr., M. I. Egbe and Adel Amer, Spectroscopy Letters 25, 1333 (1992).
[41]  Substituted-Lactones:SomeObservations ontheSynthesis and Reactivity of 4-Aroyl-3-Hydroxy-2(5H)-Furanones, H. Zimmer, R. Palmer-Sungail, D. Ho and Adel Amer, J. Heterocycl. Chem. 30, 161 (1993).
[42]  Synthesis ofNovel CrownEthersDerived of 3, 3'-Dimethyl-2, 2'-Bithienylene and Preparation of -Bis-(3-methylenethienyl)-Ethers, H. Zimmer, Adel Amer, R. Shabana, D. Ho, H. B. Mark, Jr., K. Sudsuansri and C. Striley, Acta Chem. Scand. 47, 184 (1993).
[43]  Total Synthesisof Meridinol, Epimeridinol and Related Cyclolignan, Adel Amer, H. Zimmer and F. Bauer, J. Nat. Prod. 56, 600 (1993).
[44]  Oxidative Rearrangement of thePurine Ring Using Magnesium Monoperphthalate, Adel Amer, Org. Prep. Proced. Int. 26, 353 (1994).
[45]  Synthesis of 4-(Pyrazol-3-yl)[1, 2, 4]triazolo[4, 3-a]quinoxalines and Tetrazolo analog, K. Atta, A. M. El Massry, H. A. Hamid, E. S. H. El Ashry and Adel Amer, J. Heterocycl. Chem. 31, 549 (1994).
[46]  TheCompositionof"Cu(II)-Poly(3-methylthiophene)conducting Polymer" Electrode, Xue, A. Karagozler, H. Zimmer, Adel Amer, O. Ataman and H. B. Mark, Jr., Analytical Letters 27, 1225 (1994).
[47]  Pyrolysis of N-(1-phthalazinyl)-N'-cycloalkylidenehydrazines, H. Zimmer, A. R. Safwat, D. Ho, Adel Amer and M. Badawi, J. Org. Chem. 60, 1908 (1995).
[48]  N-Substituted AminotriphenylphosphoniumTrihalidesAsNovel Brominating Agents, Adel Amer, A. Mayer, G. M. Conroy and H. Zimmer, Phosphorus, Sulfur and Silicon and The Related Elements 108, 245 (1996).
[49]  On The Structures of t-Butylaminotriphenylphosphonium Trihalides, Adel Amer, A. Mayer, D. Ho and H. Zimmer, Z. Naturforsch. 51b, 1663 (1996).
[50]  Preparation of 3-Long-Chain Substituted 5-membered Heteroarylenes and Studies on Their Langmuir-Blodgett FilmFomration, C. Striely, Adel Amer, W.-Z. Zhand, H. Zimmer and J. B. Lando, Phosphorus, Sulfur and Silicon and The Related Elements 115, 141 (1996).
[51]  Dehydration of 2-(2-Arylethyl)-2-hydroxy-4-oxopentanoic Acids and Their Hydrazones to Form Heterocycles, Adel Amer, A. M. El Massry, M. Badawi, M. M. A. Abdel Rahman and S. El Sayed and E. S. H. El Ashry, J. Prakt. Chem. 339, 20 (1997).
[52]  Synthesis and Crystal Structure Determination of Diphenyl 1-[4-nitrophenylamino]-1-Cyclohexylmethanephosphonate, Adel Amer, D. Ho and H. Zimmer, Z. Naturforsch. 52b, 1544 (1997).
[53]  Synthesis and Studies on Spectral Behaviour and Molecular Dynamics of dihydro-2-oxo-3H, 8H-furo[3, 4-b][1, 4]diazepines, H. Zimmmer, J. L. Nauss, and Adel Amer, J. Heterocycl. Chem, 35, 25 (1998).
[54]  Synthesis of 8-Substituted Xanthines and Their Oxidative Skeleton Rearrangement to 1-oxo-azaspiro[4, 5]dec-2-ene-6, 8, 10-triones, H. Zimmer, Adel Amer, F. M. Bauman, M. Haecker, C. G. M. H. J. Huber, K. Koch, K. Mahnke, C. Schumacher and R. C. Wingfield, Eur. J. Org. Chem, 2419 (1999).
[55]  A versatile Synthetic Route to Chiral Quinoxalines from Amino Acids Precursors, Ayman El Faham, Abdel Moneim El Massry and Adel Amer, Letters in peptide science, 9, 49 (2002).
[56]  A New Synthetic Approach to 4-Aroyl-3-alkoxy-2(5H)-furanones, Novel Precursors for the Preparation of Furo[3, 4-b][1, 4]-diazepine Ring SystemHans Zimmer, Christian P. Librera, Sven Hausner and Jeanette Bauer and Adel Amer, Molecules, 8, 735 (2003).
[57]  Novel and Direct Method for Preparation of 4-Amino-1, 1, 3, 3-tetrasubstituted Guanidines as well as [1, 2, 4]Triazolo Fused Heterocyclic Derivatives, M. Abdul-Ghani, S. N. Khattab, A. M. El Massry and A. El-Faham and Adel Amer, Org. Prep. Proced. Int. 36, 121 (2004).
[58]  Coupling Reaction of Hydralazine with Amino Acids and their Adducts for Antihypertensive Activities, S. N. Khattab, A. M. El Massry, A. El Faham, A. A. Bekhit and Adel Amer, J. Heterocyclic Chem.41, 387 (2004).
[59]  Synthesis and antiviral activities of 1, 2, 3-triazole functionalized thymidines:1, 3-dipolar cycloaddition for efficient regioselective diversity generation, L. Zhou, Adel Amer, M. Korn, R. Burda, J. Balzarini, E. De Clercq, E. Kern and P. F. Torrence, Antiviral Chemistry and Chemotherapy, 16, 375 (2005).
[60]  Synthesis of 3-Benzyl-2-substituted quinoxalines as a Novel Monoamine Oxidase A Inhibitors, S. Yaseen, S. Kattab, Adnan Bekhit, and AdelAmerBioorg. Med. Chem. Lett. 16, 1753-1756 (2006).
[61]  Reaction of Phthalaldehydic Acid with Different Substituted Aniline as well as Hydrazine Derivatives, S. N. Khattab and S. Yaseen A. El Faham, A. M. ElMassry, and AdelAmer. J. Heterocyclic Chem. 44, 617 (2007).
[62]  Synthesis and Antiviral Activities of New Acyclic and "Double-Headed" NucleosideAnalogues, X. Zhang, AdelAmer, X. Fan, J. Balzaini, J. Neyts, E. De Clercq, M. Prichard, E. Kern and Paul Torrence. Bioorg. Chem. 35, 221 (2007).
[63]  Synthesis, EPR and DFT calculations ofrare Ag(II)porphyrins and the crystal structure of[Zn(II)tetrakis(4-bromo-2-thiophene)porphyrin], Mohamed Ghazzali, Morsy A. M. Abu-Youssef, Krister Larsson, Örjan Hansson, Adel Amer, Toomas Tamm and Lars Öhrström Inorganic Chemistry Communications, 11, 1019 (2008).
[64]  Synthesis of Some Pyridazinylacetic acid Derivatives as a Novel Class of Monoamine Oxidase-A Inhibitors, S. N. Khattab, A. A. Bekhit, A. El-Faham, A. M. El Massry andAdel Amer, Chem. Pharm. Bull. Jpn.56, 1717 (2008).
[65]  Synthesis of New Series of quinoxaline Based MAO-Inhibitors and Docking Studies, S. N. Khattab, S. Yassin, A. Bekhit, A. M. ElMassry, V. Langer and Adel Amer. Europ. J. Med. Chem. 45, 4479 (2010).
[66]  A Regio-and Stereocontrolled Approach to triazoloquinoxalinyl C-Nucleosides, Adel Amer, M. Salah, S. Khattab, S. Yassen, V. Langer and M. El Massry Carbohydr. Res. 345, 2474 (2010)