American Journal of Medicine and Medical Sciences

American Journal of Medicine and Medical Sciences aims to promote communication among clinical researchers worldwide. This journal publishes original works within the area of clinical medicine. It is academically peer-reviewed and designed for all doctors, researchers, and health workers regardless of their medical specialties, or type of employment.


Zhaofa Xu

Editorial Board Member of American Journal of Medicine and Medical Sciences

Post-doctoral Fellow, Northwestern University Feinberg School of Medicine, Lurie Children's Hospital of Chicago, USA

Research Areas

Neuroscience, Genetics, Cell Biology, Stem cell, Biochemistry, Molecular Biology, Life Sciences

Education

2007.09-2011.06BachelorCentral South Universtiy
2011.09-2014.06MasterCentral South Universtiy
2014.09-2018.12PhDCentral South Universtiy

Experience

2018.09-2019.01visting scholar
2019.01-nowPost-doctoral fellow

Publications: Journals

[1]  Kahl M, Xu Z, Arumugam S, Edens B, Fischietti M, Zhu AC, Platanias L, He C, Zhuang X, Ma YC. m6A RNA methylation regulates mitochondrial function. Hum Mol Genet. 2024;33(11):969-80.
[2]  Miller N, Xu Z, Quinlan KA, Ji A, McGivern JV, Feng Z, Shi H, Ko CP, Tsai LH, Heckman CJ, Ebert AD, Ma YC. Mitigating aberrant Cdk5 activation alleviates mitochondrial defects and motor neuron disease symptoms in spinal muscular atrophy. Proc Natl Acad Sci U S A. 2023;120(47):e2300308120.
[3]  Hu Y, Xu Z, Pan Q, Ma L. Casein kinase 1 gamma regulates oxidative stress response via interacting with the NADPH dual oxidase complex. PLoS Genet. 2023;19(4):e1010740.
[4]  Rodrigues A, MacQuarrie KL, Freeman E, Lin A, Willis AB, Xu Z, Alvarez AA, Ma Y, White BEP, Foltz DR, Huang S. Nucleoli and the nucleoli-centromere association are dynamic during normal development and in cancer. Mol Biol Cell. 2023;34(4):br5.
[5]  Xu Z, Ma A, Ma YC. RNA methylation preserves ES cell identity by chromatin silencing of retrotransposons. Signal Transduct Target Ther. 2021;6(1):258.
[6]  Edens BM, Vissers C, Su J, Arumugam S, Xu Z, Shi H, Miller N, Rojas Ringeling F, Ming GL, He C, Song H, Ma YC. FMRP Modulates Neural Differentiation through m(6)A-Dependent mRNA Nuclear Export. Cell Rep. 2019;28(4):845-54 e5.
[7]  Xu Z, Hu Y, Deng Y, Chen Y, Hua H, Huang S, Nie Q, Pan Q, Ma DK, Ma L. WDR-23 and SKN-1/Nrf2 Coordinate with the BLI-3 Dual Oxidase in Response to Iodide-Triggered Oxidative Stress. G3 (Bethesda). 2018;8(11):3515-27.
[8]  Tan Z, Zeng H, Xu Z, Tian Q, Gao X, Zhou C, Zheng Y, Wang J, Ling G, Wang B, Yang Y, Ma L. Identification of ANKDD1B variants in an ankylosing spondylitis pedigree and a sporadic patient. BMC Med Genet. 2018;19(1):111.
[9]  Luo J, Xu Z, Tan Z, Zhang Z, Ma L. Neuropeptide receptors NPR-1 and NPR-2 regulate Caenorhabditis elegans avoidance response to the plant stress hormone methyl salicylate. Genetics. 2015;199(2):523-31.
[10]  Xu Z, Luo J, Li Y, Ma L. The BLI-3/TSP-15/DOXA-1 dual oxidase complex is required for iodide toxicity in Caenorhabditis elegans. G3 (Bethesda). 2014;5(2):195-203.
[11]  Chen J, Xu Z, Ouyang H, Peng M, Wu T, Liu J, Liu Y, Yan H. [Effect of extracts from Radix Trichosanthis on the expression of HBsAg and HBeAg in HepG2.2.15 cells]. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2012;37(1):38-41.

Publications: Conferences/Workshops/Symposiums

[1]  Molecular genetic studies of the C. elagans innate immunity-related genes unc-93 and tol-1 (The 1st Congress of Global Conference by Chinese Geneticists)
[2]  Genetic study of the biological effect of excessive iodide in C. elegans (The 3rd Chinese C. elegans Meeting)
[3]  The identification of genes mediating iodide toxicity in C. elegans (The Global Conference of Chinese Geneticists 2014 and the 13th Conference on Medical Genetics of China)
[4]  Genetic study of the biological effect of excessive iodide in C. elegans (The Annual meeting of Hunan Genetics Society in 2015)
[5]  The identification of genes affecting iodide toxicity in C. elegans (The 21st International C. elegans Conference)
[6]  Targeting mitochondrial dynamics to alleviate disease symptoms in SMA mice (The 23rd International SMA Researcher and 2nd Annual Clinical Care Meeting)