American Journal of Bioinformatics Research

American Journal of Bioinformatics Research publishes all the newest and distinguished research articles, reviews and letters in all areas of bioinformatics and computational biology. Each issue contains a series of timely, in-depth written articles by leaders in the field, covering a wide range of the integration of biology with computer and information science.

Alejandro Giorgetti

Editorial Board Member of American Journal of Bioinformatics Research

Assistant Professor, Dept of Biotechnology. University of Verona, Italy

Research Areas

Bioinformatics, computational biology

Education

2004Ph.DInternational School for Advanced Studies (SISSA),Italy
2000Master Medical Physics at the Universidad de Buenos Aires (UBA), Argentina
1996Licenciado en Fisica the Universidad Nacional del Sur (UNS). Bahia Blanca, Argentina

Experience

2011-presentAdjunct Visiting Scientist at the German Research School for Simulation Sciences (GRS). Juelich, Germany
2007-presentAssistant Professor,University of Verona, Italy
2004-2007Postdoctoral research fellow at the Department of Biochemical Sciences, University of Rome "La Sapienza". Rome, Italy
2006-2009Research fellow at the Bioinformatics Program, CRS4, Pula (CA). Sardegna, Italy

Publications: Conferences/Workshops/Symposiums/Journals/Books

[1]  Biarnés X.; Marchiori A.; Giorgetti A.*; Lanzara C.; Gasparini P.; Carloni P.; Born S.; Brockhoff A.; Behrens M.; Meyerhof W. (2010). Insights into the Binding of Phenyltiocarbamide (PTC) Agonist to Its Target Human TAS2R38 Bitter Receptor. PLOS ONE, pp. 1-6 Vol.5.
[2]  Griguoli M.; Maul A.; Nguyen C.; Giorgetti A.; Carloni P.; Cherubini E. (2010). Nicotine blocks the hyperpolarization-activated current Ih and severely impairs the oscillatory behavior of orienslacunosum molecular interneurons. THE JOURNAL OF NEUROSCIENCE, pp. 10773-10783 Vol.30.
[3]  Heller D.M.; Giorgetti A.* (2010). NMR Constraints Analyser: a web-server for the graphical analysis of NMR experimental constraints. NUCLEIC ACIDS RESEARCH, pp. W628-W632 Vol.38.
[4]  Saga G.; Giorgetti A.; Fufezan C.; Giacometti G.M.; Bassi R.; Morosinotto T. (2010). Mutation analysis of violaxanthin De-epoxidase identifies substrate-binding sites and residues involved in catalysis. THE JOURNAL OF BIOLOGICAL CHEMISTRY, pp. 23763-23770 Vol.285.
[5]  Mazzolini M.; Marchesi A.; Giorgetti A.; Torre V. (2010). Gating in CNGA1 channels. PFLUGERS ARCHIV, pp. 547-555 Vol.459.
[6]  Maullu C.; Raimondo D.; Caboi F.; Giorgetti A.; Sergi M;. Valentini M.; Tonon G.; Tramontano A. (2009). Site-directed enzymatic PEGylation of the human granulocyte colony-stimulating factor. THE FEBS JOURNAL, pp. 6741-6750 Vol.276.
[7]  Lupieri P.;Nguyen C.H.H. ;Bafghi Z.G.;Giorgetti A.;Carloni P. (2009). Computational molecular biology approaches to ligand-target interactions. HFSP JOURNAL, pp. 228-239 Vol.3.
[8]  Raimondo D., Giorgetti A.+, Bernassola F., Melino G., Tramontano A. (2008). Modelling and molecular dynamics of the interaction between the E3 ubiquitin ligase Itch and the E2 UbcH7. BIOCHEMICAL PHARMACOLOGY, pp. 1620-1627 Vol.76.
[9]  Cozzetto D, Giorgetti A, Raimondo D, Tramontano A. (2008). The Evaluation of Protein Structure Prediction Results.. MOLECULAR BIOTECHNOLOGY, pp. 1-8 Vol.39.
[10]  Albiero E., Madeo D., Ruggeri M., Bernardi M., Giorgetti A., Rodeghiero F. (2008). Loss of the JAK2 intramolecular auto-inhibition mechanism is predicted by structural modeling of a novel exon 12 insertion mutation in a case of Idiopathic Erythrocytosis. BRITISH JOURNAL OF HAEMATOLOGY, pp. 986-990 Vol.142.
[11]  Moutran A, Balan A, Ferreira LC, Giorgetti A, Tramontano A, Ferreira RC. (2007). Structural model and ligand interactions of the Xanthomonas axonopodis pv. citri oligopeptide-binding protein. GENETICS AND MOLECULAR RESEARCH, pp. 1169-1177 Vol.6.
[12]  Tress, M., Martelli, P.L., Frankish, A., Reeves, G., Wesselink J.J., Yeats, C., Olason, P.I., Albrecht, M., Hegyi H., Giorgetti, A., Raimondo, D., Lagarde, J., Laskowski, R., Lopez, G., Sadowski, M.I., Watson, J., Fariselli, P., Rossi, I., Nagy, A., Kai, W., Stoerling, Z., Orsini, M., Assenov, Y., Blakenburg, H., Huthmacher, C., Ramirez, F., Schlicker, A., Denoued, F., Jones, P., Kerrien, S., Orchard, S., Birney, E., Brunak, S., Casadio, R., Guigo, R., Harrow, J., Hermjakob, H., Jones, D.T., Lengauer, T., Orengo, C., Patthy, L., Thornton, J., Tramontano, A., Valencia, A. 2007. The implications of alternative splicing in the ENCODE protein complement PROC. NATL ACAD SCI 104: 5495-5500.
[13]  Giorgetti, A., Raimondo, D., Bosi, S. and Tramontano, A. 2007. An automatic procedure for using models of proteins in molecular replacement. PROTEINS. 15;66(3):689-96.
[14]  Nair, A.V., Mazzolini,M., Codega, P., Giorgetti, A. and Torre, V. 2006. Locking CNGA1 channels in the open and closed state. BIOPHYSICAL J. 90: 3599-3607.
[15]  Giorgetti,A., Raimondo, D., Miele, A. and Tramontano, A. 2005. Evaluating the usefulness of protein structure models for molecular replacement. BIOINFORMATICS. 21(suppl_2):ii72-ii76.
[16]  Giorgetti A, Carloni P, Mistrik P, Torre V. A Homology Model of the Pore Region of HCN channels. BIOPHYSICAL J. 89(2):932-944.
[17]  Giorgetti, A., A.V. Nair, P. Codega, V. Torre and P. Carloni. 2005. Structural Basis of Gating of CNG channels. FEBS LETTERS. 579(9):1968-1972.
[18]  Giorgetti,A., Carloni,P. 2003. Molecular Modeling of Ion Channels: Structural Predictions. Current Opinion in Chemical Biology. 7: 150-156.
[19]  Tress M., Casadio R., Giorgetti A., Hallin PF., Juncker AS., Kulberkyte E., Martelli PL., Raimondo D., Reeves GA., Thornton JM., Tramontano A., Wang K., Wesselink JJ., Valencia A., Alternative Splicing in the ENCODE Protein-Complement, Frishman D., Valencia A. Modern Genome Annotation: the Biosapiens Network, Wienn, Springer-Verlag, 2008.
[20]  Tramontano A., Jones D., Rychlewski L., Casadio R., Martelli PL., Raimondo D., Giorgetti A., Protein structure prediction, Frishman D., Valencia A. Modern Genome Annotation: the Biosapiens Network, Wienn, Springer-Verlag, 2008.
[21]  Tramontano, D. Cozzetto, A. Giorgetti, D. Raimondo. The assessment of methods for protein structure prediction in 'Protein methods and protocols'. 2nd edition. Edited by Chris Bystroff and Mohammed Zaki: The Humana Press, Inc, 2008.