International Journal of Virology and Molecular Biology

International Journal of Virology and Molecular Biology interests in all aspects of microbiology in man and animals, especially new trends and advances. It publishes general interest reviews, mini-reviews, experimental and theoretical works and computational analyses in Virology and Molecular Biology and features Wide-ranging coverage of problems related to molecular and cell biology.

Tanushree Dangi

Post-doctoral Fellow, Northwestern University Feinberg School of Medicine Chicago IL 60660, USA

Research Areas

Virology, Viral immunology, Molecular epidemiology, SARS-CoV-2, Influenza virus, Coronaviruses

Education

2018-presentPostdoctoral Research FellowNorthwestern University Feinberg School of Medicine Chicago IL 60660
2016-2018Senior Research FellowICMR-NBFGR, Lucknow India 226002
2011-2016PhDKing George's Medical University Lucknow India 226003
2005-2007MSc (Microbiology)Maharshi Dayanand Saraswati University (MDS), Ajmer India
2002-2005BSc (Biology, Chemistry)Mohanlal Sukhadia University, Udaipur India

Experience

2018-presentPostdoctoral Fellow; PI: Dr. Pablo Penaloza Macmaster
(3.5 years…ongoing)Microbiology-Immunology, Northwestern University, Chicago, IL 60011
(3.5 years…ongoing)Project: “Development of immune-modulated HIV vaccines”
2016-2018 (2 years)Senior Research Fellow; PI: Dr. Vindhya Mohindra
2016-2018 (2 years)National Bureau of Fish Genetic Resources, ICAR, Lucknow
2016-2018 (2 years)Project: de-novo genome sequencing of commercially important organism by Next Generation Sequencing”.
2010-2015 (5 years during PhD)Research Assistant (RA); PI: Prof. Amita Jain
2010-2015 (5 years during PhD)King George’s Medical University, Lucknow
2010-2015 (5 years during PhD)Project: “Multisite Epidemiological and Virological monitoring of human Influenza viruses”.

Academic Achievement

2021: Received 2021 AAI Trainee Abstract Award in Immunology supported by American Association of Immunologists (AAI) Inc. Rockville, MD, US
2014: Received International Travel Grant supported by Indian council of Medical research (ICMR) and Centre for International Co-operation in Science (CICS), Govt. of India to attend “Influenza 2014 International Conference”, St. Hilda College, Oxford, U.K. Sept 9th-11th, 2014
2009: Gold Medal awarded by Maharshi Dayanand Saraswati University, Ajmer (Rajasthan) India for getting 1st rank in Master in Science (M.Sc. Microbiology)
2008 & 2009: Qualified National eligibility test award for Lectureship supported by the Council of Scientific and Industrial Research CSIR-NET (Lectureship), Govt. of India.
2007: Qualified Graduate Aptitude Test in Engineering (GATE) in Life Science; Score: 344
2006: Received Ramabai Memorial Scholarship by MDS University Ajmer Govt. of India for getting first rank in MSc Microbiology
2000: Received Gargi & Balika Siksha Fellowship by Govt of India for getting highest rank in 10th standard at regional level
1999: Qualified Certificate of National Talent Search Contest (NTSC) awarded by Central Institute of Knowledge Learning, New Delhi (India).

Membership

American Association of Immunologists Inc. Rockville, MD, US

Publications: Journals

[1]  Dangi T, Palacio N, Sanchez S, Park M, Class J, Visvabharathy L, Ciucci T, Koralnik IJ, Richner JM, Penaloza-MacMaster P. Cross-protective immunity following coronavirus vaccination and coronavirus infection. The Journal of clinical investigation. 2021 Dec 15;131(24).
[2]  Dangi T, Class J, Palacio N, Richner JM, MacMaster PP. Combining spike-and nucleocapsid-based vaccines improves distal control of SARS-CoV-2. Cell reports. 2021 Sep 7;36(10):109664.
[3]  Sanchez S, Palacio N, Dangi T, Ciucci T, Penaloza-MacMaster P. Fractionating a COVID-19 Ad5-vectored vaccine improves virus-specific immunity. Science Immunology. 2021 Dec 1;6(66):eabi8635.
[4]  Palacio N, Dangi T, Chung YR, Wang Y, Loredo-Varela JL, Zhang Z, Penaloza-MacMaster P. Early type I IFN blockade improves the efficacy of viral vaccines. Journal of Experimental Medicine. 2020 Aug 19;217(12):e20191220.
[5]  Mohindra V, Dangi T, Tripathi RK, Kumar R, Singh RK, Jena JK, Mohapatra T. Draft genome assembly of Tenualosa ilisha, Hilsa shad, provides resource for osmoregulation studies. Scientific reports. 2019 Nov 11; 9(1): 1-4.
[6]  Mohindra V, Dangi T, Chowdhury LM, Jena JK. Tissue specific alpha-2-Macroglobulin (A2M) splice isoform diversity in Hilsa shad, Tenualosa ilisha (Hamilton, 1822). PloS one. 2019 Jul 23; 14(7).
[7]  Dangi T, Jain B, Singh AK, Singh JV, Kumar R, Dwivedi M, Verma AK, Chaddha MS and Jain A*. Molecular characterization of circulating pandemic strains of influenza A virus during 2012 to 2013 in Lucknow (India). Journal of Medical Virology, 2014; 86(12): 2134-41.
[8]   Jain A*, Dangi T, Jain B, Singh AK, Singh JV. Genetic changes in influenza A(H3N2) viruses circulating during 2011 to 2013 in northern India (Lucknow). Journal of Medical Virology, 2015; 87(8): 1268-75.
[9]  Dangi T, Jain B, Singh AK, Mohan M, Singh JV, Chaddha MS, Mishra AC and Jain A*. Influenza virus genotypes circulating in and around Lucknow, Uttar Pradesh, India, during post pandemic period, August 2010-September 2012. Indian Journal of Medical Research, 2014; 139(3): 418-26.
[10]  Singh KP*, Dangi T, JainB, Singh AK, Kumar R, Jain A*. Influenza B virus presenting as severe acute respiratory illness-a case series. Indian Journal of Medical Case Reports, 2012; 1(1): 9-12.
[11]  Jain B, Singh AK, Dangi T, Agarwal A, Verma AK, Dwivedi M, Jain A*. High prevalence of human metapneumovirus subtype B in cases presenting as severe acute respiratory illness: an experience at tertiary care hospital. The Clinical Respiratory Journal, 2014; 8(2): 225-33.
[12]  Singh AK, Jain B, Verma AK, Kumar A, Dangi T, Dwivedi M, Singh KP, Jain A*. Hospital outbreak of human respiratory syncytial virus (HRSV) illness in immunocompromised hospitalized children during summer. The Clinical Respiratory Journal, 2015; 9(2): 180-4.
[13]  Singh AK, Jain A*, Jain B, Dangi T, Kushwaha RAS, Singh JV, Mishra AC, Chaddha MS. Viral etiology of acute lower respiratory tract illness in hospitalized pediatric patients of a tertiary hospital: one year prospective study. Indian Journal of Medical Microbiology, 2014; 32(1): 13-8.
[14]  Jain B, Singh AK, Dangi T, Jain A*. Feasibility of real-time PCR over cell culture in diagnosis of Influenza virus infection: an experience of grade I viral diagnostic laboratory of developing country. International Journal of Applied Sciences and Biotechnology, 2014; 2(1): 97-102.
[15]  Jain B, Jain A*, Prakash O, Singh AK, Dangi T. In-vitro validation of self designed siRNA targeting non-structural1 gene of Influenza A virus. South Asian Journal of Experimental Biology, 2014; 4(6)
[16]  Jain B, Jain A*, Prakash O, Singh AK, Dangi T, Singh M, singh KP. In silico designing of siRNA targeting PB1 gene of Influenza A virus and in vitro validation. Journal of Applied Pharmaceutical Science, 2014; 4(08): 042-047.
[17]  Jain B, Jain A*, Prakash O, Singh AK, Dangi T, Singh M. In vitro validation of self designed "universal human Influenza A siRNA". Indian journal of Experimental Biology, 2015; 53(8): 514-21.
[18]  Singh AK, Jain A*, Jain B, Dangi T, Kushwaha RMS, Kant S, Garg R, and Prasad R. Viral etiology in patients hospitalized with Acute Exacerbations of Chronic Obstructive Pulmonary Disease (AECOPD): A case control study. International Journal of Innovation and Scientific Research, 2015; 16(2): 268-275.

Publications: Books/Book Chapters

[1]  Dangi T, Palacio NM, Sanchez S, Penaloza-MacMaster P. Characterization of cross-reactive immunity following coronavirus vaccination or natural infection. J Immunol May 1, 2021, 206 (1 Supplement) 103.13
[2]  Palacio NM, Dangi T, Chung YR, Wang Y, Loredo J, Zhang Z, Penaloza-MacMaster P. Early IFN-I limits virus-specific immunity. J Immunol May 1, 2020, 204 (1 Supplement) 171.9;
[3]  Penaloza-MacMaster PA, Chung YR, Dangi T, Penaloza-MacMaster P. Viral vaccines improve PD-1 therapy against cancer. J Immunol May 1, 2020, 204 (1 Supplement) 249.1;
[4]  Dangi T, Chung YR, Palacio N, Penaloza‐MacMaster P. Interrogating adaptive immunity using LCMV. Current Protocols in Immunology. 2020 Sep;130(1):e99.
[5]  Tanushree Dangi & Amita Jain. Influenza Virus: A Brief Overview. Proceedings of the National Academy of Sciences, India Section B: Biological Sciences 2012; 82(1): 111–121.