American Journal of Stem Cell Research

American Journal of Stem Cell Research is an international, peer-reviewed, worldwide, open access journal. It is dedicated to publishing high-quality manuscripts focusing on the biology and applications of stem cell research. The journal explains the special emphasis on basic translational and clinical research into stem cell therapeutics, including animal models and clinical trials.

Rachel Oldershaw

Editorial Board Member of American Journal of Stem Cell Research

Post-doctoral Fellow, Institute of Cellular Medicine, Newcastle University, UK

Research Areas

Human adult and embryonic stem cells, differentiation of stem cells to chondrocyte and osteoblast lineages, translational research of stem cells to orthopaedic therapies

Education

2002-2005 Ph.D.Co-funded by BBSRC, MRC and EPSRC, Faculty of Life Sciences, University of Manchester
1998-2002B.Sc. Biochemistry with Industrial Experience, The Victoria University of Manchester

Experience

2009–presentNESCI Research Fellow, North East Stem Cell Institute (NESCI), Institute of Cellular Medicine, Newcastle University
2006-2009Research Associate, North West Embryonic Stem Cell Centre, Funded by North West Development Agency, Faculty of Life Sciences, University of Manchester
2005-2006Research Associate, UK Centre for Tissue Engineering, Funded by the Department of Trade and Industry (DTI), Faculty of Life Sciences, The University of Manchester
2000-2001Pre-doctoral Research Fellow, Thomas Jefferson University Hospital, Philadelphia, USA.

Academic Achievement

British Society for Matrix Biology (BSMB) Young Investigator of the Year Award 2011
Co-applicant of JGW Patterson Foundation Trust 12 month Project Grant
Manchester BRC Pump Priming Initiative for New Technologies-Microarray
Faculty of Life Sciences Small Grant Award
Co-applicant of Arthritis Research Campaign (ARC) 36 month Project Grant
2008, British Society of Matrix Biology (BSMB) Reporter Bursary
1997, Nuffield County Scholarship

Membership

Member of British Society for Matrix Biology
Member of International Society for Stem Cell Research

Publications: Journals

[1]  Oldershaw RA. (2011) Stem cells: New cells for old. Biological Sciences Review 23, 22-25.
[2]  Oldershaw RA, Baxter MA, Lowe ET, Bates N, Grady LM, Soncin F, Brison DR, Hardingham TE, Kimber SJ. (2010) Directed differentiation of human embryonic stem cells toward chondrocytes. Nature Biotechnology 28, 1187-1194.
[3]  Oldershaw RA, Baxter MA, Lowe ET, Bates N, Grady LM, Soncin F, Brison DR, Hardingham TE, Kimber SJ. (2010) A chemically-defined protocol for generating chondrocytes from human embryonic stem cells. Nature Protocols doi:10.1038/protex.2010.201
[4]  Camarasa MV, Kerr RW, Sneddon SF, Bates N, Shaw L, Oldershaw RA, Small F, Baxter MA, Mckay TR, Brison DR, Kimber SJ. (2010) Derivation of Man-1 and Man-2 research grade human embryonic stem cell lines. In Vitro Cell Dev Biol Anim. 46, 386-94.
[5]  Oldershaw RA, & Hardingham TE. (2010) Notch signaling during chondrogenesis of human bone marrow stem cells. Bone 46, 286-93.
[6]  Fielder L, Oldershaw RA, Silverthorne K. BSMB Spring 2008 Meeting Report. International Journal of Experimental Pathology In Press.
[7]  Oldershaw RA, Tew SR, Russell AM, Meade K, Hawkins R, McKay TR, Brennan KR, Hardingham TE. (2008) Notch signaling through Jagged-1 is necessary to initiate chondrogenesis in human bone marrow stromal cells but must be switched off to complete chondrogenesis. Stem Cells 26, 666-674.
[8]  Hardingham TE, Oldershaw RA, Tew SR. (2006) Cartilage, Sox9 and Notch signals in chondrogenesis. Journal of Anatomy 209, 469-480.
[9]  Mongiat M, Fu J, Oldershaw R, Greenhalgh R, Gown AM, Iozzo RV. (2003) Perlecan protein core interacts with extracellular matrix protein 1 (ECM1), a glycoprotein involved in bone formation and angiogenesis. Journal of Biological Chemistry 278, 17491-17499.
[10]  Mongiat M, Otto J, Oldershaw R, Ferrer F, Sato JD, Iozzo RV. (2001) Fibroblast growth factor-binding protein is a novel partner for perlecan protein core. Journal of Biological Chemistry 276, 10263-10271.