International Journal of Genetic Engineering

International Journal of Genetic Engineering is devoted to the rapid publication of fundamental research papers on all phases of genetic engineering. All contributions shall be rigorously refereed and selected on the basis of quality and originality of the work as well as the breadth of interest to readers.

Roumiana Todorova

Editor-in-Chief of International Journal of Genetic Engineering

Assistant Professor, IBFBMI-BAS, Bulgaria

Research Areas

Protein Engineering, Protein Structure, Cancer Research

Education

1993PhDProtein Engineering, Moscow, Russia
1985MScSofia University, Bulgaria, Chemical Faculty, Chemistry

Experience

1994-presentIBF-BAS (now IBFBMI), Sofia, Bulgaria
1993-1994IMB-BAS, Sofia, Bulgaria
1989-1993IPR-RAS, Russia
1988Institute of Genetics-BAS, Sofia, Bulgaria

Publications: Conferences/Workshops/Symposiums/Journals/Books

[1]  Todorova R. Cloning, purification and characterization of the ribosomal protein L11 from E. coli. American Journal of Molecular Biology, 2011, 1, 33-42 doi:10.4236/ajmb.2011.11005 Published Online April 2011 (http://www.SciRP.org/journal/ajmb/)
[2]  Todorova R. MECHANISM OF TRANSACTIVATION BY EAD BASED ON PROTEIN-PROTEIN INTERACTION STUDIES. Acta Medica Bulgarica. 2010, V37(2), 58-64.
[3]  Todorova R. Estimation of methods of protein delivery into mammalian cells--a comparative study by electroporation and bioporter assay. Prikl Biokhim Mikrobiol. 2009 Jul-Aug;45(4):493-6. PubMed PMID: 19764622.
[4]  Todorova R. In vitro interaction between the N-terminus of the Ewing's sarcoma protein and the subunit of RNA polymerase II hsRPB7. Mol Biol Rep. 2009 Jul;36(6):1269-74. Epub 2008 Jul 8. PubMed PMID: 18607770.
[5]  Todorova R. and Y. Saihara Y. LINK BETWEEN RRF AND THE GTP-ASE DOMAIN OF THE BACTERIAL RIBOSOME. Biotechnol Biotechnol Equipment 2008, 23 (1), pp. 1053-1057.
[6]  Todorova R. Expression and localization of FAD2 desaturase from spinach in tobacco cells. Russ J Plant Physiol 2008, 55 (4), pp. 513-520.
[7]  Todorova R. Methods of protein delivery into mammalian cells for gene therapy and genetic studies. Acta Medica Bulgarica. 2008, V35(1), 3-11.
[8]  Todorova R, Atanasov B. The role of the salt concentration, proton, and phosphate binding on the thermal stability of wild and cloned DNA-binding protein Sso7d from Sulfolobus solfataricus. Int J Biol Macromol. 2004 Apr;34(1-2):135-47. PubMed PMID: 15178018.
[9]  Todorova RT, Saihara Y. Specific binding of ribosome recycling factor (RRF) with the Escherichia coli ribosomes by BIACORE. Mol Biol Rep. 2003 Jun;30(2):113-9. PubMed PMID: 12841582.
[10]  Todorova R. Isomerase activity of the C-terminal fructose-6-phosphate binding domain of glucosamine-6-phosphate synthase from Escherichia coli. J Enzyme Inhib. 2001 Oct;16(4):373-80. PubMed PMID: 11916143.
[11]  Todorova R, Nedev K. Effect of high concentrations of sucrose on the enzymatic activity of alpha-chymotrypsin. IUBMB Life. 2000 Jun;49(6):491-6. PubMed PMID: 11032242.
[12]  Ivanov IT, Todorova R, Zlatanov I. Spectrofluorometric and microcalorimetric study of the thermal poration relevant to the mechanism of thermohaemolysis. Int J Hyperthermia. 1999 Jan-Feb;15(1):29-43. PubMed PMID: 10193755.
[13]  Todorova R. Generation of chromophore Tyr-containing mutants of the ribosomal protein L7/L12 from Escherichia coli by site-directed mutagenesis and characterization. Int J Biochem Cell Biol. 1997 May;29(5):841-8. PubMed PMID: 9251251.
[14]  Todorova RT, Rogov VV, Vasilenko KS, Permyakov EA. Study of tyrosine-containing mutants of ribosomal protein L7/L12 from Escherichia coli. Biophys Chem. 1996 Nov 29;62(1-3):39-45. PubMed PMID: 8962470.
[15]  Todorova RT. Structure of the N-terminus of the Escherichia coli ribosomal protein L7/L12. Biochem Mol Biol Int. 1996 Jul;39(4):657-64. PubMed PMID: 8843332.
[16]  Todorova RT. [Preparation, isolation, and study of mutant forms of ribosomal protein L7/L12]. Bioorg Khim. 1993 Mar;19(3):286-92. Russian. PubMed PMID: 8489529.