American Journal of Biomedical Engineering

American Journal of Biomedical Engineering provides a forum for the publication of the latest developments in biomedical engineering, and reflects the essential multidisciplinary nature of the subject. The journal publishes in-depth critical reviews, scientific papers and technical notes.


John Nieland

Editorial Board Member of American Journal of Biomedical Engineering

Associate Professor, Aarhus School of Engineering, Denmark

Research Areas

Immunology, Biotechnology, Brain Diseases

Publications: Conferences/Workshops/Symposiums/Journals/Books

[1]  Guido Cavaletti, Arianna Cassetti, Annalisa Canta, Stefania Galbiati, Alessandra Gilardini, Norberto Oggioni, Virginia Rodriguez-Menendez, Anna Fasano, Grazia Maria Liuzzi, Ursula Fattler, Stefan Ries, John Nieland, Paolo Riccio, Heinrich Haas. Cationic liposomes target sites of acute neuroinflammation in Experimental Autoimmune Encephalomyelitis. Mol. Pharm. 2009, Apr 6.
[2]  Graversen JH, Laurberg JM, Andersen MH, Falk E, Nieland J, Christensen J, Etzerodt M, Th√łgersen HC, Moestrup SK. Trimerization of apolipoprotein A-I retards plasma clearance and preserves antiatherosclerotic properties. J Cardiovasc Pharmacol. 2008 Feb;51(2):170-7.
[3]  Kaufmann AM, Nieland JD, Jochmus I, Baur S, Friese K, Gabelsberger J, Gieseking F, Gissmann L, Glasschroder B, Grubert T, Hillemanns P, Hopfl R, Ikenberg H, Schwarz J, Karrasch M, Knoll A, Kuppers V, Lechmann M, Lelle RJ, Meissner H, Muller RT, Pawlita M, Petry KU, Pilch H, Walek E, Schneider A. Vaccination trial with HPV16 L1E7 chimeric virus-like particles in women suffering from high grade cervical intraepithelial neoplasia (CIN 2/3). Int J Cancer. 2007 Aug 23. PMID: 17721997
[4]  Caspary F, Elliott G, Nave BT, Verzaal P, Rohrbach M, Das PK, Nagelkerken L, Nieland JD. A new therapeutic approach to treat psoriasis by inhibition of fatty acid oxidation by Etomoxir. Br J Dermatol. 2005 Nov;153(5):937-44. PMID: 16225603 [PubMed-in process]
[5]  Waterboer T, Sehr P, Michael KM, Franceschi S, Nieland JD, Joos TO, Templin MF, Pawlita M. Multiplex human papillomavirus serology based on in situ-purified glutathione s-transferase fusion proteins. Clin Chem. 2005 Oct;51(10):1845-53. Epub 2005 Aug 11. PMID: 16099939 [PubMed-in process]
[6]  Kather A, Ferrara A, Nonn M, Schinz M, Nieland J, Schneider A, Durst M, Kaufmann AM. Identification of a naturally processed HLA-A*0201 HPV18 E7 T cell epitope by tumor cell mediated in vitro vaccination. Int J Cancer. 2003 Apr 1;104(3):345-53. PMID: 12569558
[7]  Da Silva DM, Velders MP, Nieland JD, Schiller JT, Nickoloff BJ, Kast WM. Physical interaction of human papillomavirus virus-like particles with immune cells. Int Immunol. 2001 May;13(5):633-41. PMID: 11312251
[8]  Kaufmann AM, Nieland J, Schinz M, Nonn M, Gabelsberger J, Meissner H, Muller RT, Jochmus I, Gissmann L, Schneider A, Durst M. HPV16 L1E7 chimeric virus-like particles induce specific HLA-restricted T cells in humans after in vitro vaccination. Int J Cancer. 2001 Apr 15;92(2):285-93. PMID: 11291058
[9]  Nieland JD, Da Silva DM, Velders MP, de Visser KE, Schiller JT, Muller M, Kast WM. Chimeric papillomavirus virus-like particles induce a murine self-antigen-specific protective and therapeutic antitumor immune response. J Cell Biochem. 1999 May 1;73(2):145-52. PMID: 10227378
[10]  Rudolf MP, Nieland JD, DaSilva DM, Velders MP, Muller M, Greenstone HL, Schiller JT, Kast WM. Induction of HPV16 capsid protein-specific human T cell responses by virus-like particles. Biol Chem. 1999 Mar;380(3):335-40. PMID: 10223336
[11]  Nieland JD, Haks MC, Kremers BL, Leupers TJ, Bakker AQ, Offringa R, Kruisbeek AM. Functional analysis of Ran/TC4 as a protein regulating T-cell costimulation. Cancer Gene Ther. 1998 Sep-Oct;5(5):259-73. PMID: 9824045
[12]  Macedo MF, Velders MP, Nieland JD, Rudolf MP, Weijzen S, Da Silva DM, Franke A, Holt G, Loviscek K, Carbone M, Kast WM. Cellular immunity and immunotherapy against deoxyribonucleic acid virus-induced tumors. Monaldi Arch Chest Dis. 1998 Apr;53(2):211-8. Review. PMID: 9689811
[13]  Nieland JD, Loviscek K, Kono K, Albain KS, McCall AR, Potkul RK, Fisher SG, Velders MP, Petersson M, Kiessling R, Kast WM. PBLs of early breast carcinoma patients with a high nuclear grade tumor unlike PBLs of cervical carcinoma patients do not show a decreased TCR zeta expression but are functionally impaired. J Immunother. 1998 Jul;21(4):317-22. PMID: 9672853
[14]  Nieland JD, Graus YF, Dortmans YE, Kremers BL, Kruisbeek AM. CD40 and CD70 co-stimulate a potent in vivo antitumor T cell response. J Immunother. 1998 May;21(3):225-36. PMID: 9610915
[15]  Greenstone HL, Nieland JD, de Visser KE, De Bruijn ML, Kirnbauer R, Roden RB, Lowy DR, Kast WM, Schiller JT. Chimeric papillomavirus virus-like particles elicit antitumor immunity against the E7 oncoprotein in an HPV16 tumor model. Proc Natl Acad Sci U S A. 1998 Feb 17;95(4):1800-5. PMID: 9465097
[16]  Velders MP, Nieland JD, Rudolf MP, Loviscek K, Weijzen S, de Visser KE, Macedo MF, Carbone M, Kast WM. Identification of peptides for immunotherapy of cancer. It is worth the effort. Crit Rev Immunol. 1998;18(1-2):7-27. Review. PMID: 9419444
[17]  Nieland JD, Kruisbeek AM. A T cell lymphoma can provide potent co-stimulatory effects to T cells that are not mediated by B7-1, B7-2, CD40, HSA or CD70. Int Immunol. 1995 Nov;7(11):1827-38. PMID: 8580081
[18]  Gravestein LA, Nieland JD, Kruisbeek AM, Borst J. Novel mAbs reveal potent co-stimulatory activity of murine CD27. Int Immunol. 1995 Apr;7(4):551-7. PMID: 7547681
[19]  Sijts AJ, De Bruijn ML, Ressing ME, Nieland JD, Mengede EA, Boog CJ, Ossendorp F, Kast WM, Melief CJ. Identification of an H-2 Kb-presented Moloney murine leukemia virus cytotoxic T-lymphocyte epitope that displays enhanced recognition in H-2 Db mutant bm13 mice. J Virol. 1994 Sep;68(9):6038-46. PMID: 7520098
[20]  Izon DJ, Nieland JD, Godfrey DI, Boyd RL, Kruisbeek AM. Flow cytometric analysis reveals unexpected shared antigens between histologically defined populations of thymic stromal cells. Int Immunol. 1994 Jan;6(1):31-9. PMID: 8148325
[21]  Jones LA, Izon DJ, Nieland JD, Linsley PS, Kruisbeek AM. CD28-B7 interactions are not required for intrathymic clonal deletion. Int Immunol. 1993 May;5(5):503-12. PMID: 7686392
[22]  Izon DJ, Nieland JD, Jones LA, Kruisbeek AM. T cell tolerance and antigen presenting cell function in the thymus. Adv Exp Med Biol. 1993;329:159-64. Review. PMID: 8379366
[23]  De Bruijn ML, Nieland JD, Schumacher TN, Ploegh HL, Kast WM, Melief CJ. Mechanisms of induction of primary virus-specific cytotoxic T lymphocyte responses. Eur J Immunol. 1992 Nov;22(11):3013-20. PMID: 1425925
[24]  De Bruijn ML, Nieland JD, Harding CV, Melief CJ. Processing and presentation of intact hen egg-white lysozyme by dendritic cells. Eur J Immunol. 1992 Sep;22(9):2347-52. PMID: 1516625
[25]  Sijts AJ, De Bruijn ML, Nieland JD, Kast WM, Melief CJ. Cytotoxic T lymphocytes against the antigen-processing-defective RMA-S tumor cell line. Eur J Immunol. 1992 Jun;22(6):1639-42. PMID: 1601045
[26]  Kruisbeek AM, Nieland JD, Jones LA. Mechanism of tolerance induction. Adv Exp Med Biol. 1992;323:101-9. Review. No abstract available. PMID: 1485558
[27]  De Bruijn ML, Schumacher TN, Nieland JD, Ploegh HL, Kast WM, Melief CJ. Peptide loading of empty major histocompatibility complex molecules on RMA-S cells allows the induction of primary cytotoxic T lymphocyte responses. Eur J Immunol. 1991 Dec;21(12):2963-70. PMID: 1660811
[28]  Neefjes JJ, De Bruijn ML, Boog CJ, Nieland JD, Boes J, Melief CJ, Ploegh HL. N-linked glycan modification on antigen-presenting cells restores an allospecific cytotoxic T cell response. J Exp Med. 1990 Feb 1;171(2):583-8. PMID: 2303788
[29]  Vasmel WL, Matthews EA, Gillis CP, Nieland J, Borst EA, Leupers CJ, Melief CJ, Slater RM. Distinct chromosomal abnormalities in murine leukemia virus-induced T-and B-cell lymphomas. Int J Cancer. 1989 Jun 15;43(6):1112-9. PMID: 2543644
[30]  Zijlstra M, Vasmel WL, Voormanns M, de Goede RE, Schoenmakers HJ, Nieland J, Slater RM, Melief CJ. Imbalanced MHC class II molecule expression at surface of murine B cell lymphomas. J Exp Med. 1986 May 1;163(5):1213-26. PMID: 3486245