International Journal of Biophysics

International Journal of Biophysics is a peer-reviewed, open access international journal that publishes original research articles as well as review articles in all areas of biophysics. The primary goal of this journal is to advance the understanding of biological structure and function by application of the principles of physical science, and by presenting the work in a biophysical context.

Yan Gu

Post-doctoral Fellow, Harvard University, USA

Research Areas

Microscopy, single molecule biology, imaging, analytical chemistry, biophysics, single cell genomics, single particle tracking, single molecule imaging


2008-2013Ph.DIowa State University


2013-presentPostdoctoral fellow, Harvard University
2011-2013Research assistant, Iowa State University
2008-2011Teaching assisitant, Iowa State University

Academic Achievement

American Chemical Society Division of Analytical Chemistry Graduate Fellowship, a prestigious fellowship awarded to 7 people nationwide, 2013
Chinese Government Award for Outstanding Self-Financed Students Abroad, a prestigious award with a cash prize of 6,000 US dollars, 2012
Joseph F. Nelson Scholarship, awarded to top one student out of 150 in the department each year based on research performance, Department of Chemistry, Iowa State University, 2012
Woman in Chemistry Award, awarded to top three female students in the department each year, Department of Chemistry, Iowa State University, 2011
Professional Advancement Travel Grant, Iowa State University, 2011
Proctor & Gamble Fellowship, awarded to top one analytical student in the department each year, Department of Chemistry, Iowa State University, 2010
Mary Helen Merriam Stewart, Female Graduate Chemistry Major Scholarship, Iowa State University, 2010

Publications: Journals

[1]  Gu Y., Sun W., Wang G., Fang N.* Single Particle Orientation and Rotation Tracking in Biophysical Studies. Nanoscale, invited featured article, doi: 10.1039/C3NR02254D (2013).
[2]  Gu Y., Wang G*, and Fang N.*, Simultaneous Single Particle Super-Localization and Rotational Tracking. ACS Nano, doi: 10.1021/nn305640y (2013).
[3]  Gu Y., Sun W., Wang G., Zimmermann Michael T., Jernigan Robert L., Fang N.* Revealing Rotational Modes of Functionalized Gold Nanorods on Live Cell Membranes. Small, doi: 10.1002/smll.201201808 (2012).
[4]  Gu Y.§, Sun W.§, Wang G., Jeftinija K., Jeftinija S. and Fang N.*, Cargo’s Rotational Dynamics at Pauses during Axonal Transport. Nature Communications, 3:1030, doi: 10.1038/ncomms2037 (2012).
[5]  Gu Y., Di X., Sun W., Wang G.* and Fang N.*, Three-Dimensional Super-Localization and Tracking of Single Gold Nanoparticles in Cells. Analytical Chemistry, 84(9), 4111-4117 (2012).
[6]  Sun W., Gu Y., Wang G., Fang N.*   Dual-Modality Single Particle Orientation and Rotational Tracking of Intracellular Transport of Nanocargos. Analytical Chemistry, 84(2), 1134-1138 (2012).
[7]  Gu Y., Sun W., Wang G., Fang N.* Single Particle Orientation and Rotation Tracking Discloses Distinctive Rotational Dynamics of Drug Delivery Vectors on Live Cell Membranes. Journal of the American Chemical Society, 133(15), 5720-5723 (2011).
[8]  Afeseh Ngwa H., Kanthasamy A., Gu Y., Fang N., Anantharam V., Kanthasamy A.G.*   Manganese nanoparticle activates mitochondrial dependent apoptotic signaling and autophagy in dopaminergic neuronal cells. Toxicology and Applied Pharmacology, 256(3), 227-240 (2011).
[9]  Luo Y., Sun W., Gu Y., Fang N.* Wavelength-Dependent Differential Interference Contrast Microscopy: Multiplexing Detection Using Nonfluorescent Nanoparticles. Analytical Chemistry, 82(15), 6675-6679 (2010).

Publications: Conferences/Workshops/Symposiums

[1]  Gu Y., Sun W., Wang G., Fang N. Rotation Modes of Gold Nanoparticles on Live Cells. PITTCON, Mar. 11-15, 2012, Orlando, FL (Oral)
[2]  Gu Y., Sun W., Wang G., Fang N. Understanding Nanoparticle Drug Delivery from Rotational Dynamics and Behaviors of Functionalized Gold Nanorods on Live Cell Membranes. 55th Annual Meeting of Biophysical Society, Mar. 5-9, 2011, Baltimore, MD (Poster)
[3]  Gu Y., Wang G., Sun W., Fang N. Distinct real-time rotational dynamics of gold nanorods modified with different functional groups on live cell membranes. 45th ACS Midwest Regional Meeting, Oct. 27-30, 2010, Wichita, KS (Oral)
[4]  Gu Y., Schmerr M.J., Fang N., Bodemer M., Ciesielczyk B., Zerr I. Detection of the Abnormal Prion Protein in Cerebral Spinal Fluid Using a Capillary Immunoelectrophoresis Assay. The international conference "Prion 2009" (Poster)