International Journal of Biophysics

International Journal of Biophysics is a peer-reviewed, open access international journal that publishes original research articles as well as review articles in all areas of biophysics. The primary goal of this journal is to advance the understanding of biological structure and function by application of the principles of physical science, and by presenting the work in a biophysical context.

Lei Zhang

Post-doctoral Fellow, The Molecular Foundry, Materials Sciences Division, Lawrence Berkeley National Laboratory, USA

Research Areas

Structure and function of Lipoprotein (including High-density lipoprotein, low-density lipoprotein, and very low-density lipoprotein); Structure and function of CETP (Cholesteryl ester transfer protein) interacting with lipoproteins;


2010Ph.D. Xi’an Jiaotong University, China
2003M.S. Xi’an Jiaotong University, China


2012-presentMember, American Heart Association
2009-2010Student Member, Biophysical Society

Academic Achievement

First Place Award, “Hejian” Scholarship, Xi’an Jiaotong University, China(2005)
Outstanding Class Cadre, Xi’an Jiaotong University, China(2009)

Publications: Journals

[1]  Minggang Xia, Shengli Zhang, Xianjun Zuo, Erhu Zhang, Shumin Zhao, Jian Li, Lei Zhang, Yachao Liu, and Run Liang, Assignment of the chiralities of double-walled carbon nanotubes using two radial breathing modes, Phys. Rev. B 70(20), 205428 (2004)
[2]  Shengli Zhang, Lei Zhang, Run Liang, Erhu Zhang, Yachao Liu, and Shumin Zhao, Lubricating bacteria model for the growth of bacterial colonies exposed to ultraviolet radiation, Phys. Rev. E 72(5), 051913 (2005).
[3]  Shengli Zhang, Run Liang, Erhu Zhang, Lei Zhang, and Yachao Liu, Magnetosubbands of semiconductor quantum wires with Rashba and Dresselhaus spin-orbit coupling, Phys. Rev. B 73, 155316 (2006).
[4]  Lei Zhang, James Song, Yvonne Newhouse, Shengli Zhang, Karl H. Weisgraber, and Gang Ren, An optimized negative-staining protocol of electron microscopy for apoE4•POPC lipoprotein, J. Lipid Research 51(5), 1228-1236 (2010)
[5]  Martin K. Jones, Lei Zhang, Andrea Catte, Ling Li, Michael Oda, Gang Ren, and Jere P. Segrest, Assessment of the Validity of the Double Superhelix Model for Reconstituted High Density Lipoproteins: A COMBINED COMPUTATIONAL-EXPERIMENTAL APPROACH, J. Biological Chemistry 285(52), 41161-41171 (2010).
[6]  Huimin Tong, Lei Zhang, Liqing Huang, and Gang Ren, Optimized Negative-staining Protocol for Electron Microscopy Study of Lipoprotein Structure, Progress in Biochemistry and Biophysics, 39(10): 972-978 (2012).
[7]  Teng Zhang, Yunhui Peng, Huimin Tong, Matthew J. Rames, Lei Zhang, Gang Ren, IPET: an Experimental Method to Determine the 3-Dimensional Structure of an Individual Macromolecule, Progress in Chemistry, 25(05): 669-676 (2013).

Publications: Books/Book Chapters

[1]  Shengli Zhang, Xing Zhang, Dongsheng Lei, and Lei Zhang, Flexible Structure of Apo A-I in 9.3 nm Spherical HDL Revealed by Molecular Dynamic Simulation, Arteriosclerosis Thrombosis and Vascular Biology 29(7), E107-E107 (2009).
[2]  Lei Zhang, Giorgio Cavigiolio, Jianjun Wang, Kerry-Anne Rye, Michael Oda, Gang Ren, Structure of 9.6nm Discoidal High-Density Lipoprotein Revealed by Individual-Particle Electron Tomography, Biophysical Journal 98(3) supplement 1, 440a (2010).
[3]  Mark Garewal, Lei Zhang, and Gang Ren, Optimized negative-staining protocol for lipid-protein interactions investigated by electron microscopy, Lipid-Protein Interactions: Methods and Protocols Methods in Molecular Biology (Clifton, NJ), Edited by Jörg Kleinschmidt, Humana Press, 974, 111-118 (2012).
[4]  Gang Ren and Lei Zhang, A 3-D Image of an Individual Protein, Biophysical Journal 104(2) supplement 1, 176a (2013).