Research in Cell Biology

Research in Cell Biology is an international peer-reviewed journal that provides a forum of experimental cell investigation, publishes reviews, original articles and short communications on the structure, function and macromolecular organization of cells and cell components. Contributions addressing cell biological problems in prokaryotes and plants are welcome.

Wouter Kalle

Editorial Board Member of Research in Cell Biology

Lecturer, Cahrles Sturt University, Australia

Research Areas

Genetics

Education

1993Ph.DFaculty of Medicine, University of Leiden, The Netherlands
1988Drs biologyUniversity of Utrecht, the Netherlands

Experience

1997-presentLecturer in Molecular Biology, School of Biomedical Sciences, Charles Sturt University, Wagga Wagga
1993-1996Post doctoral fellow at the Department of Cytochemistry and Cytometry, University of Leiden
1989-1993PhD Student at the Department of Radiation Genetics and Chemical Mutagenesis, University of Leiden

Publications: Journals

[1]  W.H.J. Kalle, A-M Hazekamp-van Dokkum, P.H.M. Lohman, A.T. Natarajan, A.A. van Zeeland and L.H.F. Mullenders. (1993) The use of streptavidin-coated beads and biotinylated antibodies to investigate induction and repair of DNA damage: Analysis of repair patches in specific sequences of UV-irradiated human fibroblasts. Analytical Biochemistry 208, 228-236.
[2]  J. Wiegant, W. Kalle, L. Mullenders, S. Brookes, J.M.N. Hoovers, J.G. Dauwerse, G.J.B. van Ommen and A.K. Raap. (1992) High-resolution in situ hybridization using DNA halo preparations. Human Molecular Genetics 1, 587-591
[3]  L.H.F. Mullenders, A-M Hazekamp-van Dokkum, W.H.J. Kalle, H. Vrieling, M.Z. Zdzienicka and A.A. van Zeeland. (1993) UV-induced photolesions, their repair and mutations. Mutation Research 299, 271-276.
[4]  M.H.P. Moers, A.G.T. Ruiter, A. Jalocha, N.F. van Hulst, W.H.J. Kalle, J.C.A.G. Wiegant and A.K. Raap (1995) Biological applications of Near Field Scanning Optical Microscopy. Proceedings SPIE 2535, 94-99
[5]  W.H.J. Kalle, M.V.E. Macville, M. van de Corput, B.G. de Grooth, H.J. Tanke and A.K. Raap. (1996) Imaging of RNA in situ hybridization with the Atomic Force Microscope (AFM). J. Microscopy, 182, 192-199
[6]  F.C.P. Braet, W.H.J. Kalle, R.B. de Zanger, B.G. de Grooth, A.K. Raap, H.J. Tanke and E. Wisse. (1996) Comparative Atomic Force and scanning electron microscopy; an investigation on cultured sinusoidal rat liver endothelial cells. J. Microscopy 181, 10-17
[7]  M.H.P. Moers, W.H.J. Kalle, A.G.T. Ruiter, J.C.A.G. Wiegant, A.K. Raap, J. Greve, B.G. de Grooth and N.F. van Hulst . (1996) Fluorescence in situ hybridization on metaphase chromosomes observed by Near-field microscopy. J. Microscopy, 182, 40-45
[8]  F. Braet, R. de Zanger, W.H.J. Kalle, A.K. Raap, H.J. Tanke, and E. Wisse. (1996) Comparative scanning, transmission and atomic force microscopy of the microtubular cytoskeleton in fenestrated liver endothelial cells. Scanning Microscopy, 10, 225-236
[9]  M.F Van Oosterwijk, R. Filon, W.H.J. Kalle, L.H.F. Mullenders and A.A. Van Zeeland. (1996) The sensitivity of human fibroblasts to n-acetoxy-2-acetylaminofluorene is determined by the extent of transcription-coupled repair, and/or their capability to counteract RNA synthesis inhibition Nucleic Acids Research. 24, 4653-4659
[10]  B. Weyn, W. Kalle, S. Kumar-Singh, E. van Marck, H. Tanke and W. Jacob (1998) Atomic force microscopy: influence of air drying and fixation on the morphology and viscoelasticity of cultured cells. J. Microscopy, 189, 172-180
[11]  Anneke van Hoffen, Wouter H.J. Kalle, Astrid de Jong-Versteeg, Alan R. Lehmann, Albert A. van Zeeland and Leon H.F. Mullenders (1999) Cells from XP-D and XP-D-CS patients exhibit equally inefficient repair of UV-induced damage in transcribed genes but different capacity to recover UV-inhibited transcription Nucleic Acids Research, 27, 2898-2904
[12]  Ho KY, Kalle WH, Lo TH, Lam WY, Tang CM (1999) Reduced expression of APC and DCC gene protein in breast cancer. Histopathology 35, pp 249-256
[13]  Crispin R. Dass, Todd L. Walker, Wouter H.J. Kalle and Mark Burton (1999) A microsphere-lipoplex (microplex) vector for targeted gene therapy of cancer. I. Construction and in vitro evaluation Drug Delivery, 6, pp 259-270
[14]  Crispin R. Dass, Todd L. Walker, Wouter H.J. Kalle and Mark Burton (2000) A microsphere-lipoplex (microplex) vector for targeted gene therapy of cancer. II. N Vivo biodistribution studyin a solid tumor model. Drug Delivery, 7, pp 15-20
[15]  Melanie Cochrane, Wouter Kalle, Paul Roffey & Helen Moriarty (2002) The detection of Chlamydia pneumoniae in atherosclerotic plaques of Australian subjects Pathology 34 pp 270-274
[16]  Jason C. Steel, Heather M.A. Cavanagh, Mark A. Burton and Wouter H.J. Kalle (2004) Microsphere–liposome complexes protect adenoviral vectors from neutralising antibody without losses in transfection efficiency, in-vitro. Journal of Pharmacy and Pharmacology 56 pp. 1371-1378
[17]  MY Kwan, W Kalle, GTC Lau, JKC Chan (2004) Is gliomatosis peritonei derived from the associated ovarian teratoma? Human Pathology, 35 pp 685-688
[18]  Jason C. Steel, Heather M. A. Cavanagh , Mark A. Burton , Daniel Dingwall and Wouter H. J. Kalle (2004) In-vitro evaluation of ion-exchange microspheres for the sustained release of liposomal–adenoviral conjugates Journal of Controlled Release 95 pp 601-611
[19]  Jason C. Steel, Wouter H. Kalle, Daniel Dingwall, Heather Cavanagh, Mark A. Burton (2004) Pre-treatment with a non-therapeutic dose of cisplatin increases solid tumour response to liposomal-p53 gene therapy. Cancer Therapy 2 pp 239-244
[20]  JC Steel, HMA Cavanagh, MA Burton, WHJ Kalle (2005) Microsphere Delivery of Adenoviral-Liposome Complexes Reduces Adenoviral Immunogenicity and Allows Successful Re-Administration of the Virus without Loss of Gene Expression Efficiency Molecular Therapy
[21]  Jason C. Steel, Heather M.A. Cavanagh, Mark A. Burton, Daniel J. Dingwall and Wouter H.J. Kalle (2005) Modification of liposomal concentration in liposome/adenoviral complexes allows significant protection of adenoviral vectors from neutralising antibody, in vitro Journal of Virological Methods, 126 pp 31-36
[22]  Thordarson P, Atkin R, Kalle WJH, Warr GG, Braet F (2006) Developments in using scanning probe microscopy to study molecules on surfaces-from thin films and single-molecule conductivity to drug-living cell interactions. Aust J Chem 59 pp 359-375.
[23]  Jason C. Steel, Heather M.A. Cavanagh, Mark A. Burton, Mones S. Abu-Asab, Maria Tsokos, John C. Morris and Wouter H.J. Kalle (2007) Increased tumor localization and reduced immune response to adenoviral vector formulated with the liposome DDAB/DOPE. European Journal of Pharmaceutical Sciences 30 pp 398-405
[24]  Yim Tong Szeto, Shirley Chin Yee Wong, Julia Mai Wing Mong, Iris F.F. Benzie, Wouter Kalle, Sok Cheong Pak (2011) In vitro anti-oxidation activity and genoprotective effect of selected Chines medicinal herbs The American Journal of Chinese Medicine 39 pp 827-838

Publications: Books/Book Chapters

[1]  Wisse E, Braet F, Kalle W, de Grooth B, Raap A, Tanke H. (1995) Atomic force microscopic investigation of endothelial fenestrae. In: Bailey GW, Ellisman MH, Hennigar RA, Zaluzec NJ, eds. Proc. Microscopy and Microanalysis. New York: Jones and Begell Publishing, 1995:890-891
[2]  W.H.J. Kalle, F. Braet, A.K. Raap, E. Wisse and H. Tanke. (1997) Imaging of the membrane surface of sinusoidal rat liver endothelial cells by atomic force microscopy) In: E. Wisse, D.L. Knook And C. Balabaud (eds)., Cells of the hepatic sinusoid 6, Kupfer cell foundation, Leiden, 94-96.
[3]  W.H.J. Kalle, Philip Bwititi and Todd Walker (2009) Article I. Fluorescence in Clinical Diagnosis In: Ewa M. Goldys (ed), Fluorescence applications in biotechnology and life sciences, John Wiley & Sons, Inc.