Research in Cell Biology

Research in Cell Biology is an international peer-reviewed journal that provides a forum of experimental cell investigation, publishes reviews, original articles and short communications on the structure, function and macromolecular organization of cells and cell components. Contributions addressing cell biological problems in prokaryotes and plants are welcome.

Antonio Tiezzi

Editorial Board Member of Research in Cell Biology

Professor, Tuscia University, Italy

Research Areas

Cell Biology, Natural Substances, Sexual Plant Reproduction

Experience

2007-presentPresident of the Electron Microscopy Centre (CIME), University of Tuscia, Viterbo
1997-2003Director of the Electron Microscopy Centre (CIME), University of Tuscia, Viterbo
1992-presentAssociate Professor of Plant Cytology, University of Tucia, Viterbo
1985-1992Researcher at the Department of Environmental Sciences (including the Institute of Botany), University of Siena
1982-1985Researcher at the Sclavo Research Center, Sclavo Pharmaceutic Company SpA, Siena
1979-1981Fellow Researcher, Institute of Botany, University of Siena
1978Sclavo Fellow Student of the Biology Faculty, University of Siena
1977Sclavo Fellow Student of the Biology Faculty, University of Siena

Academic Achievement

Italian Member of the ECF Board (European Cytoskeleton Forum), 1998-2006
PhD Thesis Invited Opponent, Univ. of Helsinki (SF), 1997
Eur. Communities Fellowship, Univ. of Wageningen (NL), 1987
Sclavo Research Fellowship, AECOM Yeshiva University New York (USA), 1983
Eur. Mol. Biol. Org. (EMBO) Fellowship, Biozentrum Basel (CH), 1981

Membership

Member of the Novartis List of Cell Biology Experts, 1996-2000 (list termed)
European Cytoskeleton Forum
Italian Society of Botany
Accademia dei Fisiocritici (Siena)
Accademia Kronos
FIARNS 09

Publications: Conferences/Workshops/Symposiums/Journals/Books

[1]  TIEZZI A., FOCARDI S., CIAMPOLINI F., CRESTI M. La componente lipidica dell'essudato stigmatico di Citrus limon (L.) Burm. GIORN. BOT. ITAL., 115: 95-101, 1981.
[2]  CIAMPOLINI F., CRESTI M., SARFATTI G., TIEZZI A. Ultrastructure of the stylar canal cells of Citrus limon (Rutaceae) PLANT SYST. EVOL. 138, 263-274, 1981.
[3]  TIEZZI A., CRESTI M., CIAMPOLINI F. La composizione chimica dell'essudato stigmatico di Citrus limon (L.) Burm. GIORN. BOT.ITAL., Vol.116, n.3-4, 189-199, 1982.
[4]  PALLINI V., MENCARELLI C., BRACCI L., CONTORNI M., RUGGIERO P., TIEZZI A., MANETTI R. Cytoplasmic nucleoside triphosphatases similar to axonemal dynein occur widely in different cell types J. SUBMICROSC. CYTOL., 15(1), 229-235, 1983.
[5]  RUGGIERO P., TIEZZI A., BUGNOLI M., PALLINI V. Immunoreactive analogues of brain microtubule-associated protein (MAP2) in mammalian kidney and liver J. SUBMICROSC. CYTOL. 16(1), 131-132, 1984.
[6]  MANETTI R., CECCARINI C., GUAZZI G.C., FEDERICO A., TIEZZI A., COSTANTINO-CECCARINI E. Immunohistochemical study of cultured skin fibroblast from giant axonal neuropathy. Pathology of the intermediate filament protein. ACTA NEUROLOGICA, Vol. 7 (XL), No 3/4, JUNE-AUGUST 1985, 358-362.
[7]  CRESTI M., CIAMPOLINI F., TIEZZI A. Ultrastructural studies on Nicotiana tabacum pollen tubes grown in diofferent culture medium (preliminary results). ACTA BOT. NEERL., 35(3): 285-292, 1986.
[8]  CRESTI M., KEIJZER C.J., TIEZZI A., CIAMPOLINI F., FOCARDI S. Stigma of Nicotiana: ultrastructural and biochemical studies. AMER. J. BOT., 73(12): 1713-1722, 1986.
[9]  BONOMO R., TIEZZI A. Influenza di regolatori di crescita e fungicidi su polline di melo in vivo ed in vitro. RIV. ORTOFLOROFRUTT. IT., 70, 43-52, 1986.
[10]  HESLOP-HARRISON J., HESLOP-HARRISON Y., CRESTI M., TIEZZI A.,CIAMPOLINI F. Actin during pollen germination J. CELL SCI., 86, 1-8, 1986.
[11]  TIEZZI A., MOSCATELLI A., MILANESI C., CIAMPOLINI F., CRESTI M. Taxol-induced structures derived from cytoskeletal elements of the Nicotiana pollen tube. J. CELL SCI., 88, 657-661, 1987.
[12]  MANETTI R., CECCARINI C., GUAZZI GC., FEDERICO A., TIEZZI A., BUGNOLI M., COSTANTINO CECCARINI E. Characterization of the intermediate filament apparatus in skin fibroblast from patients with giant axonal neuropathy: effect of trypsin. CELL MOTIL. CYTOSKEL., 8: 55-60, 1987.
[13]  CRESTI M., MILANESI C., TIEZZI A., CIAMPOLINI F., MOSCATELLI A. Ultrastructure of Linaria vulgaris pollen grains. ACTA BOT. NEERL., 37(3): 379-386, 1988.
[14]  TIEZZI A., MOSCATELLI A., CRESTI M. Taxol-induced microtubules from different sources: an ultrastructural comparison. J. SUBMICROSC. CYTOL. PATHOL., 20(3): 613-617, 1988.
[15]  HESLOP-HARRISON J., HESLOP-HARRISON Y., CRESTI M., TIEZZI A., MOSCATELLI A. Cytoskeletal elements, cell shaping and movement in the angiosperm pollen tube. J. CELL SCI., 91: 49-60, 1988.
[16]  TIEZZI A., MOSCATELLI A., CAI G., CIAMPOLINI F., CRESTI M. Cytoskeletal proteins in the pollen tube of Nicotiana tabacum. New studies with taxol. GIORN.BOT.IT., Vol. 122, No 1-2, 1988, 88-89.
[17]  MOSCATELLI A, TIEZZI A., CAI G., CIAMPOLINI F., CRESTI M. Cytoskeletal proteins in pollen tubes. GIORN.BOT.IT., Vol.122, No 1-2, 1988, 90-91.
[18]  DI SIMPLICIO P., TIEZZI A., MOSCATELLI A., BIANCO MT., CRESTI M. The SH-SS exchange reaction between the Ellman's reagent and protein containing SH groups as a method for determining conformational states: tubulin. ITAL. J. BIOCHEM., Vol.38(2): 83-90, 1989.
[19]  CHEN F., CIAMPOLINI F., TIEZZI A., CRESTI M. The ultrastructure of polymorphic pollen grains of Canna indica L. SEX. PLANT REPROD. 2: 193-198, 1989.
[20]  WAGNER V.T., CRESTI M., SALVATICI P., TIEZZI A. Changes in volume, surface areas and density of nuclear pores on the vegetative nucleus of tobacco in dry, hydrated and activated conditions. PLANTA, 181: 304-309, 1990.
[21]  BARTALESI A., MOSCATELLI A., DEL CASINO C., CAI G., TIEZZI A. Confocal laser scanning microscopy of the microtubular system of diving generative cell in Nicotiana tabacum. GIORN. BOT. ITAL, 125, n.1-2: 21-28, 1991.
[22]  TIEZZI A. The pollen tube cytoskeleton. ELECTRON MICROSCOPY REVIEWS. SUBCELLULAR AND BIOMOLECULAR STRUCTURE, Vol. 4: 205-219, 1991, Pergamon Press.
[23]  PALEVITZ B.A., TIEZZI A. The organization, composition and function of the Generative cell and sperm cytoskeleton INTERNATIONAL REVIEW OF CYTOLOGY. Vol 140: 149-185, 1992.
[24]  TIEZZI A., MOSCATELLI A., CAI G., BARTALESI A., CRESTI M. An immunoreactive homolog of mammalian kinesin in Nicotiana tabacum pollen tube. CELL MOTIL. CYTOSKEL., 21: 132-137, 1992.
[25]  B.Q HUANG, PIERSON E.S., RUSSELL S.D., TIEZZI A., CRESTI M. Video microscopic observations of living, isolated embryo sacs of Nicotiana and their component cells. SEX. PLANT REPROD., 5(2): 156-162, 1992.
[26]  DEL CASINO C., TIEZZI A., WAGNER V.T., CRESTI M. The organization of the cytoskeleton in the generative cell and sperms of Hyacinthus orientalis. PROTOPLASMA 168: 41-50, 1992.
[27]  TIEZZI A., CAI G., CRESTI M. Il citoscheletro negli organi riproduttori delle angiosperme GIORN. BOT. ITAL., Vol 126, n.2: 177-185, 1992.
[28]  B.Q. HUANG, PIERSON E.S., RUSSELL S.D., TIEZZI A., CRESTI M. Cytoskeletal organization and modification during pollen tube arrival, gamete delivery and fertilization in Plumbago zeylanica ZYGOTE, 1 (May): 143-154, 1993.
[29]  CAI G., BARTALESI A., DEL CASINO C., MOSCATELLI A., TIEZZI A., CRESTI M. The kinesin immunoreactive homologue from Nicotiana tabacum pollen tube: biochemical properties and subcellular localization. PLANTA, 191: 496-506, 1993.
[30]  DEL CASINO C., LI Y.Q., MOSCATELLI A., SCALI M., TIEZZI A., CRESTI M. Distribution of microtubules during growth of tobacco pollen tubes. BIOLOGY OF THE CELL, 1993, vol. 79, n.2, 125-132.
[31]  TIRLAPUR U.K., SCALI M., DEL CASINO C., CAI G., MOSCATELLI A., TIEZZI A., CRESTI M. Confocal images analysis of spatial variations in immunocytochemically identified calmodulin during pollen hydration, germination and pollen tube tip growth in Nicotiana tabacum ZYGOTE, 1994, vol. 2 (February), 63-68.
[32]  LIU G.Q., DEL CASINO C.,CAI G., TIEZZI A., CRESTI M., YEN L.F. Identification of kinesin-like protein on Golgi vesicles of pollen ACTA BOTANICA SINICA, 1994, 36(1), 7-10.
[33]  LI Y.Q., FALERI C., THOMPSON R.D., TIEZZI A., EIJLANDER R., CRESTI M. Cytochemical immunolocalization of the abundant pistil protein Sk2 in potato (Solanum tuberosum) SEX PLANT REPROD, 1994, 7: 164-168.
[34]  DEL CASINO C., TIEZZI A., SCALI M., NERI G., MOSCATELLI A. The influence of vinyl cyclohexene dioxide on the cytoskeleton of cultured mouse fibroblasts: immunofluorescence investigations. TOXICOLOGY in VITRO, 1994 Vol.8 (6): 1277-1283.
[35]  LIU G.Q., CAI G., DEL CASINO C., TIEZZI A., CRESTI M. A Kinesin-Related Polypeptide is Associated with Vesicles from Corylus avellana Pollen. CELL MOTILITY AND THE CYTOSKELETON, 1994, 29: 155-166.
[36]  SCALI M., CAI G., DEL CASINO C., SANTUCCI A., TIRLAPUR U.K., MOSCATELLI A., CRESTI M., TIEZZI A. Purification and biochemical characterization of calmodulin from Corylus avellana pollen. PLANT PHYSIOLOGY AND BIOCHEMISTRY, 1994, 32 (6): 831-838.
[37]  LIU G.Q., YEN L.F., CAI G., DEL CASINO C., TIEZZI A., CRESTI M. Binding of pollen golgi vesicles to calf brain microtubule in vitro. ACTA BOTANICA SINICA, 1994, 36 (11): 860-863.
[38]  TIEZZI A., DEL CASINO C., LOZZI L., CAI G., SCALI M., DAINELLI L., MOSCATELLI A. Un anticorpo contro il sito enzimatico della dineina Atti della Accademia dei Fisiocritici, Siena, serie XV, Tomo XIII, 1994.
[39]  MOSCATELLI A., DEL CASINO C., LOZZI L., CAI G., SCALI M., TIEZZI A., CRESTI M. High molecular weight polypeptides related to dynein heavy chains in Nicotiana tabacum pollen tubes J. CELL SCIENCE, 1995, 108: 1117-1125.
[40]  TIRLAPUR U.K., FALERI C., MILANESI C., MOSCATELLI A., SCALI M., DEL CASINO C., TIEZZI A., CRESTI M. High-resolution confocal imaging and colloidal-gold immuno-electron microscopy of changes in distribution of myosin during pollen hydration, germination and pollen tube growth in Nicotiana tabacum L. EUR. J. CELL BIOLOGY, 1995, 67: 209-217.
[41]  ZHANG H.Q., BOHDANOWICZ J., PIERSON E.S., LI Y.Q., TIEZZI A., CRESTI M. Microtubular organization during asymmetrical division of the generative cell in Gagea lutea J. PLANT RESEARCH, 1995, 108: 269-276.
[42]  MENCARELLI C., TIEZZI A., RUGGIERO P., CONTORNI M., MASSONE A., MOSCATELLI A., PALLINI V. Heterogeneous localization of epitopes along axonemes of mammalian cilia BIOLOGY OF THE CELL, 1995, 83 (2): 179-184.
[43]  CAI G., MOSCATELLI A., DEL CASINO C.,CHEVRIER V., MAZZI M.,TIEZZI A.,CRESTI M. The anti-centrosome monoclonal antibody 6C6 reacts with a plasma membrane-associated polypeptide of 77kDa from Nicotiana tabacum pollen tubes PROTOPLASMA, 1996, 190: 68-78.
[44]  POGGIALINI C., MOROZZI G., MARCOLONGO R., VIGNANI R., CRESTI M:,TIEZZI A. Antinuclear human autoantibodies as markers in Nicotiana tabacum pollen tubes ACTA SOCIETATIS BOTANICORUM POLONIAE, 1996, 65 (1-2): 69-72.
[45]  MOSCATELLI A., CAI G., LIU G.Q., TIEZZI A., CRESTI M. Dynein-related polypeptides in pollen and pollen tubes SEXUAL PLANT REPRODUCTION, 1996, 9:312-317.
[46]  MOLINELLI L., TIEZZI A., LUSINI P., BOVALINI L., DI STEFANO A., MARTELLI P. Dark effects of 8-MOP on HeLa Cells ATTI ACCADEMIA DEI FISIOCRITICI, SIENA, 1997.
[47]  GENUALDO G., ERRICO A., TIEZZI A., CONICELLA C. a-tubulin and F.actin distribution during microsporogenesis in a 2n pollen producer of Solanum GENOME, 1998, 41: 636-641.
[48]  RONDINI S., OVIDI E., TADDEI A.R., CECI M., RAMBELLI A., TIEZZI A. Estratti di foglie di Aloe arborescens presentano attività citotossica su cellule di mieloma murino ATTI ACCADEMIA DEI FISIOCRITICI, SIENA, 1999, serie XV, tomo XVIII, 27-32.
[49]  MOROZZI G., POGGIALINI C., CUCINI S., DAINELLI L., CAI G., TIEZZI A., BELLISAI F., BACARELLI M.R., PUCCI G., SIMPATICO A., MARCOLONGO R., GALEAZZI M. Sieri umani riconoscono componenti di cellule vegetali RIVISTA ITALIANA DI BIOLOGIA E MEDICINA, 1999, 19: 41-48.
[50]  CAI G., ROMAGNOLI S., MOSCATELLI A., OVIDI E., GAMBELLINI G., TIEZZI A., CRESTI M. Identification and characterization of a novel microtubule-based motor associated with membranous organelles in pollen tubes The PLANT CELL, 2000, 12: 1719-1736.
[51]  RONDINI S., OVIDI E., TADDEI A.R., TIEZZI A. Estratti da foglie di Aloe arborescens testati su cellule di mieloma murino: aspetti ultrastrutturali e citologici ACTA PHYTOTHERAPEUTICA, settembre 2000, vol.III, 3, 122-128.
[52]  OVIDI E., SBORCHIA A.M., D'ALESSANDRO B., RONDINI S., IETTA F., PAULESU L., DI STEFANO A., CUSI M.G., CAI G., TIEZZI A. Dati preliminari sulla valutazione di molecole ad attività citotossica da estratti di foglie di Aloe arborescens ATTI ACCADEMIA DEI FISIOCRITICI, SIENA, 2000, Serie XV, Tomo XIX, 81-86.
[53]  OVIDI E., GAMBELLINI G., TADDEI A.R., CAI G., DEL CASINO C., CECI M., RONDINI S., TIEZZI A. Herbicides and the microtubular apparatus of Nicotiana tabacum pollen tube: immunofluorescence and immunogold labelling studies TOXICOLOGY IN VITRO, 2001, VOL 15, 2: 143-151.
[54]  SCOCCIANTI V., OVIDI E., TADDEI A.R., TIEZZI A., CRINELLI. L., GENTILINI L., SPERANZA A. Involvment of the ubiquitin/proteasome pathway in the organisation and polarised growth of kiwifruit pollen tubes SEXUAL PLANT REPRODUCTION 2003, 16:123-133.
[55]  DATTILO D., BRACCHINI L., OVIDI E., TIEZZI A., ROSSI C. Il polline ed il tubetto pollinico di Actinidia deliciosa (Kiwi) come bioindicatori per la valutazione degli effetti di campi elettromagnetici a bassa frequenza ATTI ACCADEMIA DEI FISIOCRITICI DI SIENA, 2003, Serie XV, Tomo XXII, 159-168.
[56]  DATTILO A.M., BRACCHINI L., LOISELLE S.A., OVIDI E., TIEZZI A., ROSSI C. Morphological anomalies in pollen tubes of Actinidia deliciosa (Kiwi) exposed to 50 Hz magnetic field. BIOELECTROMAGNETICS, 2005, 26:153-156.
[57]  CAI G., OVIDI E., ROMAGNOLI S., VANTARD M.,CRESTI M., TIEZZI A. Identification and characterization of plasma membrane proteins that binds to microtubules in pollen tube and generative cells of tobacco PLANT and CELL PHYSIOLOGY, 2005, 46: 563-578.
[58]  TRIGGIANI D., CECCARELLI D., OVIDI E., RAGIONIERI M.P., TIEZZI A. Rubus ulmifolius leaf molecoles show antiproliferative activity on murine, rat and human cancer cell lines HERBAL of AGRARIAN SCIENCE of UZBEKISTAN, 2005, 4(22): 108-109.
[59]  MUNZI S., TRIGGIANI D., CECCARELLI D., CLIMATI E., TIEZZI A., PISANI T., LOPPI S Effetti di estratti lichenici da specie del genere Peltigera su cellule di mieloma murino NOTIZIARIO DELLA SOCIETÀ LICHENOLOGICA ITALIANA. 2008, 21: 55.
[60]  TRIGGIANI D., CECCARELLI D., TIEZZI A., PISANI T., MUNZI S., GAGGI C., LOPPI S. Antiproliferative activity of lichen extracts on murine myeloma cells BIOLOGIA, 2009, 64(1): 59-62.
[61]  BEDINI C., CACCIA R., TRIGGIANI D., MAZZUCATO A., SORESSI G.P., TIEZZI A Micropropagation of Aloe arborescens Mill-; a step towards efficient production of its valuable leaf extracts showing antiproliferative activity on murine myeloma cells PLANT BIOSYSTEMS, 2009, vol. 143, (2): 233-240.
[62]  MAMADALIEVA N.Z., EGAMBERDIYEVA D., JANIBEKOV A.A., TRIGGIANI D., TIEZZI A. Testing of biological properties of the plant Silene viridiflora CHEMISTRY OF NATURAL COMPOUNDS, 2009, 45(4): 589-590.
[63]  MAMADALIEVA N.Z, KUCHERBEV K.J., NAUBEEV T.H., UTENIYAZOV K.K., ISAEV M.I., EGAMBERDIYEVA D., TRIGGIANI D., TIEZZI A. Cytotoxic properties of cycloartane glycosides from the plants of Astragalus genus growing in the Republic of Karakalpakstan CHEMISTRY OF NATURAL COMPOUNDS, 2009,.
[64]  OVIDI E., TADDEI A.R. CECCARELLI D., TIEZZI A. Il polline ed il tubetto pollinico di Actinidia deliciosa: indagini morfologiche condotte per mezzo di della microscopia elettronica e ottica confocale ITALUS HORTUS 16(5),2009: 144-149.
[65]  MAMADALIEVA NZ., EGAMBERDIYEVA D., CLIMATI E., TRIGGIANI D., CECCARELLI D., SULTANOV S.S., NIGMATULLAEV A.M., Sh.S. AZIMOVA SH.S, TIEZZI A. The cytotoxic activities of four Salvia species native from Uzbekistan UZBEK BIOLOGY JOURNAL, 2009, 3-7.
[66]  MAMADALIEVA N.Z., CLIMATI E., TRIGGIANI D., CECCARELLI D., EGAMBERDIEVA D., TIEZZI A. In vitro assays to investigate cytotoxic properties of Lamiaceae family plant extracts UZBEK BIOLOGY JOURNAL, 2010, 7-10.
[67]  F. MASTROGIOVANNI, E. OVIDI, A. TIEZZI, G.M. BALESTRA, A. QUATTRUCCI Plant Biomolecules as possible tools against tomato phytobacterial infections J. Horticultural Sciences, in stampa