Research in Neuroscience

Research in Neuroscience is a peer-reviewed journal aims to advance our understanding of the nervous system in health and disease, thereby improving the diagnosis and treatment of neuropsychiatric and neurodegenerative disorders. It presents novel results that can be of interest to a broad spectrum of neuroscientists and that were generated by experiments guided by clearly defined aims or hypotheses.


Pragney Deme

Post-doctoral Fellow, Postdoctoral Fellow,Johns Hopkins University School of Medicine,600 N Wolf Street, Pathology 605,Baltimore, MD 21287, USA, USA

Research Areas

Pharmaceutical sciences, Biochemistry, Analytical chemistry, Mass spectrometry, lipidomics, Metabolomics, Cardiovascular diseases, Neurodegenerativ diseases

Education

12/06/2003-05/18/2006Bachelors in Chemistry, Physics and MathematicsOsmania University, India
12/6/2007-15/05/2019Master of Science In ChemistryOsmania University, India
08/02/2010-24/11/2014PhD in Bioanalytical ChemistryOsmania University, India
08/02/2010-02/02/2015PhD research in mass spectrometry based drug PKPD studies and pesticide residue analysis in foods Council of Scientific and Industrial Research-Indian Institute of Chemical Technology-India

Experience

09/03/2016-02/07/2018Postdoc Fellow in the College of Medicine, University of Central Florida,Orlando, Florida 32826, USA
03/02/2015-20/02/2016Analytical Scientist, Clearsynth Laboratory, Hyderabad, India

Academic Achievement

1. Margaret Moffett award for the poster presentation of “Myeloperoxidase mediated oxidation of aldehydes and atherosclerosis”. At 5th international academy of cardiovascular sciences 2017, Orlando, Florida, USA.
2. Fellow- Council of Scientific and Industrial Research (CSIR)-IICT
3. State 2nd rank -2006, for MSc chemistry entrance exam conducted by Kakatiya University, Warangal, TS.
4. Silver medal in Intermediate (+II education) -2003, for securing highest grade in the SRM Junior College, Pitlam, TS, India.
5. Reviewer Board Member - Journal of Pharmaceutical and Biological Sciences (IP Innovative Publication Pvt Ltd).
6. Editorial Board Member - Journal Science Letters (The Science publishers)

Membership

International Society for neurovirology (ISNV)
American Society for Mass Spectrometry (ASMS)
American Heart Association (AHA)
Greater Boston Mass Spectrometry Discussion Group (GBMSDG)
American association of neurology (AAN)
Indian Association of Analytical Scientists (IAAS)
Editorial Board Member - Journal Science Letters (The Science publishers)
Editorial Board Member – Asian Journal of Pharmaceutics
Editorial Board Member- IP International Journal of Comprehensive and Advanced Pharmacology (Ip Innovative Publication Pvt.Ltd.)
Reviewer Board Member -Journal of Pharmaceutical and Biological Sciences (IP Innovative Publication Pvt Ltd)
Reviewer Board Member -International Journal of Food Science and Biotechnology (Science Publishing Group)

Publications: Journals

[1]  Identification and evaluation of anti-inflammatory properties of aqueous extract components of sesame oil (sesumum indicum). Pragney Deme, Chandrakala Aluganti Narasimhulu and Sampath Parthasarathy. Journal of Chromatography B. 1087-1088 (2018) 61-69. doi:10.1016/j.jchromb.2018.04.029
[2]  A novel mechanism for atherosclerotic calcification-potential resolution of the oxidation paradox, Aladdin Riad*, Chandrakala Aluganti Narasimhulu*, Pragney Deme* and Sampath Parthasarathy. Antioxidants and Redox signaling, 29 (2018) 471-483. doi: 10.1089/ars.2017.7362. (*-Equal Contribution)
[3]  Ultra performance liquid chromatography atmospheric pressure photoionization high resolution mass spectrometric determination of multiclass pesticide residues in fruit juices. Pragney Deme and Vijayasaradhi Upadhyayula. Food Chemistry, 173 (2015) 1142-1149.
[4]  An improved dispersive solid-phase extraction clean-up method for the gas chromatography–negative chemical ionization tandem mass spectrometric (GC-NCI-MS) determination of multiclass pesticide residues in edible oils. Pragney Deme et al., Food Chemistry, 142 (2014) 144–151.
[5]  LC-MS/MS Determination of Organophosphorus pesticide residues in coconut water. Pragney Deme et al., Food Analytical Methods, 6 (2013) 1162–1169.
[6]  Effect of background derivatization on the signal enhancement of pesticide residues extracted from edible oils. Pragney Deme et al., Journal of Separation Science, 36 (2013) 3926–3933.
[7]  Simultaneous determination of Amlodipine, Valsartan and Hydrochlorothiazide by LC- ESI-MS/MS and its application to pharmacokinetics in rats. Ganesh Shanker* and Pragney Deme* et al., Journal of pharmaceutical analysis, 6 (2014) 399-406. (*-Equal Contribution)
[8]  Simultaneous determination of atorvastatin calcium and olmesartan medaxomil by LC- ESI-MS/MS and its application to pharmacokinetics in rats. G. Shanker Ganesh* and Pragney Deme* et al., International Journal of Pharmacy and pharmaceutical Analysis, 6 (2014) 464- 468. (*-Equal Contribution).
[9]  Evaluation of anti-inflammatory properties of herbal aqueous extracts and their chemical characterization. Pragney Deme, Chandrakala Aluganti Narasimhulu, Sampath Parthasarathy. Journal of medicinal food. 22(2019) 861-873.
[10]  Cypate and cypate-glucosamine as near infrared (NIR) fluorescent probes for in vivo tumor imaging. Mona Doshi, Daniel A Nierenberg, Orielyz Flores-Fernandez, Pragney Deme Annette R Khaled, Sampath Parthasarathy. Molecular Pharmacology, March 6, 2019, mol.118.114199;
[11]  Monocarboxylate Transporter MCT1 in Schwann Cells Maintains Long-term Myelin and Axonal Integrity of Sensory Nerves by Modulating Lipid Metabolism. Mithilesh Kumar Jha, Youngjin Lee, Katelyn A. Russell, Fang Yang, Raha M. Dastgheyb, Pragney Deme Xanthe H. Ament Weiran Chen Ying Liu Yun Guan Michael J. Polydefkis Ahmet Hoke Norman J. Haughey Jeffrey D. Rothstein Brett M. Morrison. Glia, 2019, 1-17.
[12]  Lipidomic Characterization of Extracellular Vesicles in Human Serum (jnlcb-18-0024.R2). Suming. C, Amrita. KD, Pragney. D, Raha. D, Pavan. B, Norman JH. Journal of Circulating Biomarkers. Accepted on September 10.2019.