International Journal of Diabetes Research

International Journal of Diabetes Research publishes reports of experimental and clinical research on diabetes mellitus and metabolism. Original contributions on morphological, biochemical, physiological and clinical aspects of research on diabetes and metabolism are welcome. The role of the journal is to provide a venue for dissemination of knowledge and discussion of topics related to diabetes clinical research and patient care.

Bhaskar Ponugoti

Editorial Board Member of International Journal of Diabetes Research

Research Scientist, University of Pennsylavania, USA

Research Areas

Molecular and Cell Biology, Cell Signaling, Diabetes and Obesity


2009Ph.D.University of Illinois, Urbana. (Molecular Physiology)
2004M.Sc Illinois State University, Normal. (Biotechnology)
2000B.Sc A.N.G.R. Agricultural University, India. (Agriculture)


2011-presentResearch Associate, University of Pennsylvania, Philadelphia
2009-2011Postdoctoral Researcher, University of Pennsylvania, Philadelphia
2006-2008 Teaching Assistant, University of Illinois, Urbana
2004-2009Research Assistant, University of Illinois, Urbana
2002-2004Research Assistant, Illinois State University, Normal

Academic Achievement

2003, Phi Sigma
2003, R. D. Weigel Research Fellowship, Illinois State University, Normal
2004-2005, Fellow, School of Molecular and Cellular Biology, University of Illinois, Urbana

Publications: Conferences/Workshops/Symposiums/Journals/Books

[1]  Papasani MR, Gensure R, Postlethwait JH, Gunes Y, Yan Y.-L, Ponugoti B, Jüppner H, Rubin DA. Identification and Characterization of the Zebrafish and Fugu Gene Encoding Tuberoinfundibularpeptide of 39 residues (TIP39). Endocrinology 145(11): 5294-5304, 2004.
[2]  Gensure RC, Ponugoti B, Gunes Y, Papasani MR, Bastepe M, Rubin DA, Jüppner H. Identification and Characterization of Two Parathyroid Hormone-like Molecules in Zebrafish. Endocrinology 145 (4): 1634-1639, 2004.
[3]  Fang S, Miao J, Xiang L, Ponugoti B, Treuter E, Kemper JK. Coordinated recruitment of histone methyltransferase G9a and other chromatin-modifying enzymes in SHP-mediated regulation of hepatic bile acid metabolism. Molecular and Cellular Biology, 27(4): 1407-24, 2007.
[4]  Ponugoti B, Fang S, Kemper JK. Functional interaction of hepatic nuclear factor-4 and peroxisome proliferator-activated receptor-gamma coactivator 1alpha in CYP7A1 regulation is inhibited by a key lipogenic activator, sterol regulatory element-binding protein-1c. Molecular Endocrinology, Nov; 21(11):2698-712, 2007.
[5]  Fang S, Tsang S, Jones R, Ponugoti B, Yoon H, Wu SY, Chiang CM, Willson TM, Kemper JK. The P300 acetylase is critical for ligand-activated farnesoid X receptor (FXR) induction of SHP. Journal of Biological Chemistry 283: 35086-35095, 2008.
[6]  Kemper JK, Xiao Z#, Ponugoti B#, Miao J#, Fang S, Kanamaluru D, Tsang S, Wu SY, Chiang CM, Veenstra TD. FXR acetylation is normally dynamically regulated by p300 and SIRT1 but constitutively elevated in metabolic disease states. (# ZX, BP, and SF equally contributed). Cell Metabolism, Nov; 10 (5):392-404, 2009.
[7]  Ponugoti B, Xiao Z, Miao J, Zang M, Wu SY, Chiang CM, Veenstra TD, Kemper JK. SIRT1 Deacetylates and Inhibits SREBP-1C Activity in Regulation of Hepatic Lipid Metabolism. Journal of Biological Chemistry 285(44): 33959-33970, 2010.
[8]  Diehl JA, Ponugoti B. Ubiquitin mediated proteolysis in G1/S phase control its relationship with tumor susceptibility. Genes & Cancer, July; 1: 717-724, 2010.