International Journal of Diabetes Research

International Journal of Diabetes Research publishes reports of experimental and clinical research on diabetes mellitus and metabolism. Original contributions on morphological, biochemical, physiological and clinical aspects of research on diabetes and metabolism are welcome. The role of the journal is to provide a venue for dissemination of knowledge and discussion of topics related to diabetes clinical research and patient care.

Abdoreza Davoodi-Semiromi

Editorial Board Member of International Journal of Diabetes Research

Assistant Professor, University of Florida, USA

Research Areas



2001-2004Advanced Post-doc College of Medicine, University of Florida
1999-2001post-doc, College of Medicine, University of Florida
1998Ph.D Duncan Guthrie Institute of Medical Genetics, University of Glasgow, Glasgow, UK
1991M.Sc Developmental Biology, Tehran, Iran
1979B.Sc University of Ahwaz-Ahwaz-Iran


2010Research Assistant Professor, Department of Pharmacotherapy & Translational Research, College of Pharmacy, University of Florida, Gainesville, USA
2009-2010Appointed to the University of Central Florida Institutional Animal Care and Use Committees (IACUC) committee
2007Research Faculty in Medicine, Department of Molecular Biology and Microbiology, College of Medicine, University of Central Florida, Orlando, FL, USA
2004-2007Research Assistant Professor, Department of Pathology, Immunology and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, USA
2001-2004Advanced JDRFI Post-doc fellow, Department of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, USA
1999-2001JDRFI Post-doc fellow, Department of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, USA
1997-1999Post-doc fellow, Department of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, USA
1994-1997Duncan Guthrie Institute of Medical Genetics, University of Glasgow, Glasgow, UK
1991-1993Lecturer at the Azad University, Iran

Academic Achievement

NIH-R21(1R21 A176394-01)-September 1st, 2009-August 30, 2011
JDRF Mucosal Immunity Innovative grant, 2008,
The AAI 2006 Junior Faculty Travel award, Miami South Beach 2007, FL
JDRF Innovative Grant (JDRF 5-2006-937),
JDRF Research Grant,
The AAI 2006 Junior Faculty Travel award, Boston May 2006, MA
The ADS8 travel award, Osaka, Japan
JDRF Transition Award to the Faculty position (JDRF 10-2001-589)
JDRF Advanced Post-doc fellowship
JDRF Post-doc fellowship


American Society of Human Genetics, since 1999
American Association of Immunology, since 2002
American Association of Diabetes, since 2007

Publications: Conferences/Workshops/Symposiums/Journals/Books

[1]   Davoodi-Semiromi, A., Melissa Schreiber, Samson Nallapali, Dheeraj Verma, Nameirakpam Dolendro Singh, Robert K. Banks, Debopam Chakrabarti and Henry Daniell. Chloroplast-derived vaccine antigens confer dual immunity against cholera and malaria by oral or injectable delivery, Plant Biotechnol J. 2010 Feb;8(2):223-42. Epub 2009 Dec 28.
[2]   Davoodi-Semiromi, A., Samson N., Dainell H., The Green Vaccine: A global strategy to combat infectious and autoimmune diseases. Hum Vaccin. 2009 Jul 23; 5(7).
[3]   F. Seydel, E. Garrigan, B. Stutevoss, N. Belkin, B. Makadia, J. Carter, J.-D. Shi, A. Davoodi-Semiromi, M. McDuffie, and S.A. Litherland GM-CSF induces STAT5 binding at epigenetic regulatory sites within the Csf2 promoter of non-obese diabetic (NOD) mouse myeloid cells. J Autoimmun. 2008 Oct 20.
[4]   Philip A. Arlen, Michael Singleton, Jeffrey J. Adamovicz, Yi Ding, Abdolreza Davoodi-Semiromi and Henry Daniell, Effective plague vaccination via oral delivery of plant cells expressing F1–V antigens in chloroplasts Infect Immun. May 27. 2008
[5]   Davoodi-Semiromi, A., Mc Duffie, M., Litherland, S., Clare-Salzler M. Truncated pStat5B is associated with Idd4 locus in NOD mice. Biochem. Biophys. Res. Commun. 2007 May 11;356(3):655-61. Epub 2007 Mar 13.
[6]   Murawski, MR., S. Litherland, M. Clare-Salzler and Davoodi-Semiromi, A. Up regulation of Foxp3 expression in mouse and human Treg is IL-2/STAT5 dependent ; Implications for the NOD STAT5 mutation in diabetes pathogenesis. Ann N Y AcadSci. 2006 Oct;1079:198-204
[7]   Malini Laloraya, Abdoreza Davoodi-Semiromi, G. Pradeep Kumar, Marcia McDuffie, and Jin-Xiong She (2006) Impaired Crkl Expression Contributes to the Defective DNA Binding of Stat5b in Nonobese Diabetic Mice, Diabetes 2006 55: 734-741.
[8]  Litherland, S.A., T.X. Xie, K.M. Grebe, A. Davoodi-Semiromi, J. Elf, N.S. Belkin, L.L Moldawer, and M.J. Clare-Salzler. 2005. Signal Transduction Activator of Page 6 of 12 Transcription 5 (STAT5) Proteins are Dysfunctional in Autoimmune Monocytes & Macrophages. J Autoimmunity. 2005, June;24(4): 297-310, Epub 2005 Mar23.
[9]  Davoodi-Semiromi, A., Laloraya, M., Kumar, PG., Purohit, S., Jha, RK and She, J-X., A mutatnt Stat5B with weaker DNA binding affinity defines a key defective pathway in Non-Obese diabetic (NOD) mice (JBC, e-published December 29, 2003 on line). J Biol Chem. 2004 Mar 19;279(12):11553-61. Epub 2003 Dec 29.
[10]   Karen H. S. Wilson, Quan-Zhen Li, Abdoreza Davoodi-Semiromi, Qing-Guo Ruan, Sarah Eckenrode, Yang, Jing-Da Shi,, Richard A. McIndoe, Byron P. Croker and Jin-Xiong She (2003) Microarray analysis of gene expression in the kidneys of new and post onset diabetic NOD mice. Diabetes. 2003 Aug;52(8):2151-2159.
[11]   Wang, C-W, Davoodi-Semiromi A., shi, J-D., …. and She, J-X (2003) High resolution mapping and mutation analyses of candidate genes in the Urofacial syndrom (UFS) critical region. Am J Med Genet 2003 May 15;119A(1):9-14.
[12]   Davoodi-Semiromi, A., Yang, J., and She, J-X (2002) IL-12 is associated with type 1 diabetes Diabetes. 2002 Jul;51(7):2334-6.
[13]   Quan-Zhen Li, Cong-Yi Wang, Jin-Da Shi, Qing-Guo Ruan, Sarah Eckenrode, Abdoreza Davoodi-Semiromi, Thomas Kukar, Yunrong Gu, Wei Lian, Donghai Wu and Jin-Xiong She (2001) Molecular cloning and characterization of the mouse and human TUSP gene, a novel member of the tubby superfamily. Gene 2001 Aug 8; 273(2): 275-284.
[14]   Pradeep Kumar, Malini Laloraya, Cong-Yi Wang, Qing-Guo Ruan, Abdoreza Davoodi-Semiromi, K.J. Kao, and Jin-Xiong She (2001) The autoimmune regulator (AIRE) is a DNA-binding protein . J Biol Chem. 2001 Nov 2;276(44):41357-64.
[15]   Jing-Da Shi, Thomas Kukar, Cong-Yi Wang, Quan-Zhen Li, Pedro E. Cruz, Abdoreza Davoodi-Semiromi, Ping Yang, Yunrong Gu, Wei Lian, Donghai Wu and Jin-Xiong She, Molecular Cloning and Characterization of A Novel Mammalian Endo-Apyrase (LALP1) J Biol Chem. 2001 May 18;276(20):17474-8.
[16]   Davoodi-Semiromi, A., Lanyon G., Davidson, R., and Connor, J. M. (2000). Aberrant RNA splicing in the hMSH2 gene: molecular identification of three aberrant RNA in Scottish patients with colorectal cancer in the West of Scotland. American Journal of Medical Genetics, 95:49-52, 2000.
[17]   Wang CY, Shi JD, Huang YQ, Cruz PE, Ochoa B, Hawkins-Lee B, Davoodi-Semiromi A, She JX. Construction of a physical and transcript map for a 1-Mb genomic region containing the urofacial (Ochoa) syndrome gene on 10q23-q24 and localization of the disease gene within two overlapping BAC clones (<360 kb). Genomics. 1999 Aug 15;60(1):12-9.
[18]   Wang, C.Y., Shi, J.D., Davoodi-Semiromi, A. and She, J.X. Cloning of Aire, the mouse homologue of the autoimmune regulator (AIRE) gene responsible for autoimmune polyglandular syndrome Genomics 55 (3), 322-326 (1999). Page 7 of 12
[19]   Cong-Yi, Wang., A. Davoodi-Semiromi, ., Wei Huang., Ellen Connor., Jin-Da Shi., Jin-Xiong She (1998). Characterisation of mutations in Patients with autoimmune polyglandular syndrome type 1 (APS 1).