Journal of Microbiology Research

Journal of Microbiology Research aims to publish all the latest and outstanding research articles, reviews and letters in all areas of major importance to techniques of microbiology and applied research. It publishes high quality research and review papers on novel aspects of microbiology, including environmental, food, agricultural, medical, pharmaceutical, veterinary, soil, water and biodeterioration.


Havard Jenssen

Editorial Board Member of Journal of Microbiology Research

Associate Professor, Roskilde University, Denmark

Research Areas

Microbiology, Drug Discovery, Infectious Diseases, Antimicrobial Peptides

Education

2004Ph.DPeptide chemistry, virology and statistical analysis University of Tromso
1999C.E.Biotechnology University of Tromso
1997B.ScBiochemistry Oslo College of Engineering

Experience

2009Associate Professor at Dept. of Sci., Systems & Models, Roskilde University, Denmark
2005-2009Post. Fellow & Research Associate at CMDR, University of British Colombia, Canada
2000Research Associate at Dept. of Microbiology, University Hospital of North Norway

Publications: Conferences/Workshops/Symposiums/Journals/Books

[1]  Andersen J.H., Jenssen H., Gutteberg T.J., Lactoferrin and lactoferricin inhibit herpes simplex 1 and 2 infection and exhibit synergy when combined with acyclovir, Antiviral Res., 2003, 58, 209-215.
[2]  Andersen J.H., Jenssen H., Sandvik K., Gutteberg T.J., Anti-HSV activity of lactoferrin and lactoferricin is dependent on the presence of heparan sulphate at the cell surface, J. Med. Virol., 2004, 74, 262-271.
[3]  Jenssen H., Andersen J.H., Uhlin-Hansen L., Gutteberg T.J., Rekdal Ø., Antiviral activity of linear or cyclic lactoferricin analogues in relation with heparan sulfate affinity, Antiviral Res., 2004, 61, 101-109.
[4]  Jenssen H., Mantzilas D., Andersen J.H., Gutteberg T.J., A wide range of medium sized, highly cationic, alpha-helical peptides show antiviral activity against Herpes simplex virus, Antiviral Res., 2004, 64, 119-126.
[5]  Jenssen H., Gutteberg T.J., Lejon T., Modelling of anti-HSV activity of lactoferricin analogues using amino acid descriptors, J. Pept. Sci., 2005, 11, 97-103.
[6]  Hunter H.N., Demcoe A.R., Jenssen H., Gutteberg T.J., Vogel H., Human Lactoferricin is Partially Folded and Distinct from Bovine Lactoferricin., Antimicrob. Agents Chemother., 2005, 49:3387-3395.
[7]  Samuelsen Ø., Haukland H.H., Jenssen H., Krämer M., Sandvik K., Ulvatne H., Vorland L.H., Induced resistance to an antimicrobial peptide in staphylococcus aureus., FEBS letter, 2005, 579:3421-3426.
[8]  Jenssen H., Anti Herpes Simplex Virus Activity of Lactoferrin/Lactoferricin-an Example of Antiviral Activity of Antimicrobial Protein/Peptide., Mol. Cell. Life Sci. 2005, 62, 3002-3013.
[9]  Jenssen H., Gutteberg T.J., Lejon T., Modelling the anti-HSV activity of small, cationic peptides using amino acid descriptors, J Pept. Res. 2005, 66. Suppl. 1:48-56.
[10]  Jenssen H., Gutteberg T.J., Rekdal Ø., Lejon T., Prediction of activity, synthesis and biological testing of anti-HSV active peptides., Chem. Biol. Drug Design, 2006, 68: 58-66.
[11]  Mistry N., Drobni P., Näslund J., Sunkari G.V., Jenssen H., Evander M., The anti-papillomavirus activity of human and bovine lactoferricin, Antiviral Res., 2007, 75:258-265.
[12]  Jenssen H., Lejon T., Hilpert K., Fjell C., Cherkasov A., Hancock R.E.W., Evaluating different descriptors for model design of antimicrobial 12-mer peptides with enhanced activity towards P. aeruginosa., Chem. Biol. Drug Design, 2007, 70: 134-142.
[13]  Jenssen H., Fjell C.D., Cherkasov A., Hancock R.E.W., QSAR modeling and computer-aided design of antimicrobial peptides., J. Pept. Sci, 2008, 14: 110-114.
[14]  Jenssen H., Sandvik K., Andersen J.H., Hancock R.E.W., Gutteberg T.J., The anti-HSV mode of action to lactoferrin and lactoferricin., Antiviral Res., 2008 79: 192-198.
[15]  Fjell C.D., Jenssen H., Fries P., Aich P., Griebel P., Hilpert K., Hancock R.E.W., Cherkasov A., Identification of novel host-defense peptides and the absence of alpha-defensins in the bovine genome., Proteins., 2008 73:420-430.
[16]  Hamill P., Brown K., Jenssen H., Hancock R.E.W., Novel Anti-Infectives: Is Host Defence the Answer?, Curr. Opinion in Biotech., 2008 19(6): 628-636.
[17]  Jenssen H, Hancock R.E.W., Antimicrobial properties of lactoferrin., Biochimie, 2009 91(1): 19-29.
[18]  Marr A.K., Jenssen H., Moniri M.R., Hancock R.E.W., Panté N., Bovine lactoferrin and lactoferricin interfere with intracellular trafficking of herpes simplex virus 1., Biochimie, 2009 91(1): 160-164.
[19]  Cherkasov A., Hilpert K., Jenssen H., Fjell C.D., Waldbrook M., Mullaly S., Volkmer R., Hancock R.E.W., Use of artificial intelligence in the design of small peptide antibiotics effective against a broad spectrum of highly antibiotic resistant superbugs., ACS Chem. Biol., 2009 4(1): 65-74.
[20]  Hilpert K., Elliott M., Jenssen H., Kindrachuk J., Fjell C.D., Körner J., Winkler D.F.H., Weaver L.L., Henklein P., Ulrich A.S., Chiang S.H.Y., Farmer S.W., Pante N., Volkmer R., Hancock R.E.W., Screening and characterization of surface-tethered cationic peptides for antimicrobial activity. Chem. & Biol., 2009 16(1): 58-69.
[21]  Jenssen H., Antiviral mode of action of Lactoferrin and Lactoferricin-A model system for design of antiviral peptides with enhanced activity towards Herpes simplex virus. Tromsø, Norway, 2004. ISBN 82-7589-150-7.
[22]  Jenssen H., Gutteberg T.J., Lejon T., Modelling of anti-HSV activity of lactoferricin analogues using amino acid descriptors, pp 394-395 in; QSAR & molecular modelling in rational design of bioactive molecules, Ed. Aki E. and Yalcin I., Computer aided drug design & development society in Turkey, Ankara, Turkey, 2005. ISBN 975-00782-0-9 (Proceedings).
[23]  Jenssen H., Antimicrobial activities of lactoferrin and lactoferrin derived peptides, Chapter 1 (pp 1-60) in; Dietary protein research trends, Nova Science Publishers Inc. Hauppauge, NY, USA, 2007. ISBN 1-60021-607-2.
[24]  Jenssen H., Aspmo S.I., Serum stability of peptides., Chapter 10; in Peptide-Based Drug Design, Methods Mol Biol. 2008;494:177-86, Humana Press, Totowa, NJ, USA, 2008, ISBN 978-1-58829-990-1.
[25]  Jenssen, H.; Hilpert, K.; Hancock, R.E. In 30th Euopean peptide symposium, 2008; (Proceedings).
[26]  Jenssen, H.; Hancock, R. E., Therapeutic potential of HDPs as immunomodulatory agents. Methods Mol Biol 2010, 618, 329-47.
[27]  Petersen P.D., Kindrachuk J., Jenssen H., Immune modulation for treatment of HSV, In Advances in medicine and biology, vol 41, Berhardt L.V. Ed. Nova Science Publishers Inc.: Happauge, 2012.