American Journal of Chemistry

American Journal of Chemistry is a peer-reviewed chemistry journal. It is aimed to publish all the latest and outstanding research articles, reviews and letters in all areas of Chemistry.

Wenjiao Song

Post-doctoral Fellow, Weill Cornell Medical College, USA

Research Areas

Chemical biology, biochemistry, chemistry


2005-2010Ph. D.University at Buffalo, SUNY, Buffalo,NY,USA
2000-2003M. S.Beijing Normal University, Beijing, China
1996-2000B. S.Beijing Normal University, Beijing, China


2010-presentPostdoctoral Associate, Department of Pharmacology, Weill Medical College of Cornell University, Laboratory of Dr. Samie Jaffrey
2005-2010Graduate student, Department of Chemistry, University at Buffalo, SUNY, Laboratory of Dr. Qing Lin
2003-2004Assistant Researcher, Chinese Research Academy of Environmental Sciences, Beijing, China
2000-2003Research Assistant, Analytical and Testing Center, Beijing Normal University, Beijing, China


The New York Academy of Sciences

Publications: Journals

[1]  W. Song, Rita L Strack & Samie R Jaffrey. Plug-and-play fluorophores extend the spectral properties of Spinach. J Am Chem Soc. 2014 Jan 6.
[2]  Rita L Strack, W. Song & Samie R Jaffrey. Using Spinach-based sensors for fluorescence imaging of intracellular metabolites and proteins in living bacteria. Nat Protoc. 2014 Jan;9(1):146-55.
[3]  W. Song, Rita L Strack & Samie R Jaffrey. Imaging bacterial protein expression using genetically encoded RNA sensors. Nature Methods. 2013, 10 873–875
[4]  J.Paige, T. Nguyen-Duc, W. Song, S. Jaffrey. Fluorescence imaging of cellular metabolites with RNA. Science. 2012, 335(6073):1194.
[5]  J. Wang, W. Zhang, W. Song, Y. Wang, Z. Yu, J. Li, M. Wu, L. Wang, J. Zang, and Q. Lin. A Biosynthetic Route to Photoclick Chemistry on Protein. J. Am. Chem. Soc. 2010, 132 (42), 14812–14818
[6]  W. Song, Y. Wang, C. I. Rivera Vera, J. Qu, and Q. Lin. A Metabolic Alkene Reporter for Spatiotemporally Controlled Imaging of Newly Synthesized Proteins in Mammalian Cells. ACS Chem. Biol., 2010, 5 (9), 875–885
[7]  W. Song, Z. Yu, M. M. Madden, and Q. Lin. A Bioorthogonal Chemistry Strategy for Probing Protein Lipidation in Live Cells. Mol. BioSyst., 2010, 6, 1576 - 1578
[8]  M. M. Madden, C. I. Rivera Vera, W. Song, and Q. Lin. Facile Synthesis of Stapled, Structurally Reinforced Peptide Helices via A Photoinduced Intramolecular 1,3-Dipolar Cycloaddition Reaction. Chem. Commun., 2009, 5588 - 5590.
[9]  Y. Wang, W. Song, W. J. Hu, and Q. Lin. Fast Alkene Functionalization In Vivo by Photoclick Chemistry: HOMO Lifting of Nitrile Imine Dipoles. Angew. Chem. Int. Ed. 2009, 121, 5434 - 5437.
[10]  W. Song, Y. Wang, J. Qu, M. M. Madden, and Q. Lin. A Photoinducible 1,3-Dipolar Cycloaddition Reaction for Rapid, Selective Modication of Tetrazole-Containing Proteins. Angew. Chem. Int. Ed. 2008, 47, 2832-2835.
[11]  W. Song, Y. Wang, J. Qu, and Q. Lin. Selective Functionalization of a Genetically Encoded Alkene-containing Protein via “Photoclick Chemistry” in Bacterial Cells. J. Am. Chem. Soc. 2008, 130, 9654-9655.
[12]  M. M. Madden, W. Song, P. G. Martell, Y. Ren, J. Feng, and Q. Lin. Substrate Properties of Ubiquitin Carboxyl-Terminally Derived Peptide Probes for Protein Ubiquitination. Biochemistry 2008, 47, 3636-3644.
[13]  Y. Wang, W. J. Hu, W. Song, R. K. Lim, and Q. Lin. Discovery of Long-wavelength Photoactivatable Diaryltetrazoles for Bioorthogonal 1,3-dipolar Cycloaddition Reactions. Org. Lett. 2008, 10, 3725-3728.
[14]  W. Song, C. Zhao, and X. Zhao. Determination of Mercury in Biological Reference Material by Hydride Generation Inductively Coupled Plasma Atomic Emission Spectrometry. Chinese Journal of Analytical Laboratory, 2003, 22, 428-430.
[15]  W. Song, C. Zhao, and X. Zhao. Determination of Lead in Biological Reference Material by Hydride Generation Inductively Coupled Plasma Atomic Emission Spectrometry. Modern Instrument, 2003, 44, 22-24.
[16]  W. Song, Z. Wu, X. Wang, and L. Lu. The Preparation and Bio-distribution of New Kidney Imaging Agent 99mTc-TTHA. Journal of Beijing Normal University (Natural Science), 2001, 37, 92-95.

Publications: Conferences/Workshops/Symposiums

[1]  W. Song, and Q. Lin Book Chapter “In Vitro and In Vivo Screening: Methods of High-throughput Screening” in Protein Surface Recognition: Approaches for Drug Discovery, Giralt, E., Peczuh, M., Salvatella, X. Ed. Wiley-VCH, 2011, 251-271