American Journal of Medicine and Medical Sciences

American Journal of Medicine and Medical Sciences aims to promote communication among clinical researchers worldwide. This journal publishes original works within the area of clinical medicine. It is academically peer-reviewed and designed for all doctors, researchers, and health workers regardless of their medical specialties, or type of employment.


Michael LaPointe

Editorial Board Member of American Journal of Medicine and Medical Sciences

Associate Professor, Indiana University Northwest, USA

Research Areas

Membrane Transport, Acid Base Regulation, Hypertension, Renal Physiology, Cell Calcium Regulation

Education

1988Ph.DDepartment of Physiology and Biophysics; University of Illinois at Chicago, (Illinois University School of Medicine), Chicago, Illinois
1979B.S.Department of Biology and Department of Classical Studies, Loyola University, Chicago, Illinois

Experience

2009-presentAssociate Professor, Department of Biology, Indiana University Northwest (IUN) Gary, IN
2004-presentAdjunct Assistant Professor of Cellular and Integrative Physiology, Northwest Center for Medical Education, Indiana University School of Medicine
2004-2009Assistant Professor, Department of Biology, Indiana University Northwest (IUN) Gary, IN
1993-2005Assistant Professor of Research, Department Medicine, Division of Nephrology; Northwestern University, Feinberg School of Medicine, Chicago, IL
1992-2004Research Biologist, VA Chicago Health Care System-Lakeside Division, Chicago, IL
1992-1993Instructor, Department Medicine; Northwestern University, Chicago, IL
1988-1992Postdoctoral Research Associate, Department Medicine; Northwestern University, Chicago, IL
1988-1990Research Technician, Lakeside VA, Chicago, IL
1986-1988Research Technologist, Northwestern University, Chicago, IL
1978Production Technician, MediPhysics, Rosemont, IL

Academic Achievement

Founders Day Teaching Award nominee (2006, '08, '09, '10, '11)
IUN Trustees Teaching Award external nomination (2008, '09)
Outstanding Teacher Recognition, IUN Center of Excellence in Teaching and Learning (CETL), 2006
Invited Seminar Speaker-CETL Workshop, Grading Tests with Technology: Instant and Easy, 2011
Invited Seminar Speaker-Indiana University Northwest (Anthropology Club) Darwin Day, 2008
Invited participant (consultant) Anatomy & Physiology Digital Symposia, McGraw Hill, Jan 2008
Invited seminar speaker-Purdue University Calumet, Dept Biology, 2006
Invited seminar speaker-Indiana University Medical School, Gary, 2004
Invited seminar speaker-Chicago Medical School, Dept. of Physiology, 1997
Invited seminar speaker-American Heart Assoc. of Metropol. Chicago Research Meeting, 1994
Invited seminar speaker-Chicago College of Osteopathic Medicine, 1992
Guest Physiology lecturer-Chicago College of Osteopathic Medicine, 1992
Invited seminar speaker-UIC Medical School, Dept of Physiology and Biophysics, 1991
Travel Grant-American Society of Nephrology, 1993
Travel Grant-International Society of Nephrology, 1990
Travel Grant-American Society of Hypertension, 1989
Pre-doctoral Teaching Assistantship-NIH, 1980-1986
Illinois State Scholarship, 1974-1978
Loyola University Scholarship, 1974-1978
Illinois State Scholar, 1974
National Merit Scholar Finalist, 1974

Membership

American Association of University Professors (AAUP) (2005-2009)
American Association for the Advancement of Science (1987-present)
American Society of Nephrology (1988-2005)
American Heart Association, Council for High Blood Pressure Research (1997-2001)
American Heart Association, Council for Basic Research (1997-2001)
International Society of Nephrology (1987-1999)
Midwest Salt and Water Club (inducted 1994)
Tri Beta Biology Honor Society (inducted 2005)

Publications: Conferences/Workshops/Symposiums/Journals/Books

[1]  Valles P, LaPointe MS, Wysocki J, and Batlle D: Kidney vacuolar H+-ATPase: Physiology and Regulation. Seminars in Nephrology 26(5):361-374, 2006.
[2]  Valles P, Wysocki J, Salabat MR, Cokic I, LaPointe MS, and Batlle D: Angiotensin II increases H+ ATPase B1 subunit expression in medullary collecting ducts. Hypertension 45(4): 818-823, 2005.
[3]  Ye M, Wysocki J, Naaz, P, Salabat MR, LaPointe MS, and Batlle D: Increased ACE2 and decreased ACE protein in renal tubules from diabetic (db/db) mice:A renoprotective combination? Hypertension 43(5): 1120-1125, 2004.
[4]  LaPointe MS, Sodhi C, Sahai A, and Batlle D: Na+/H+ exchange activity and NHE-3 expression in renal tubules from the spontaneously hypertensive rat. Kidney International 62(1): 157-165, 2002.
[5]  LaPointe MS and Batlle D: Cultured skin fibroblasts as an in vitro model to assess phenotypic features of diabetic nephropathy (editorial). American Journal of Kidney Disease 38(3): 646-647, 2001. .
[6]  Stakisaitis D, LaPointe MS, and Batlle D: Mechanisms of chloride transport in thymic lymphocytes. American Journal of Physiology, Renal Physiology 280 (2):F314-F324, 2001.
[7]  Danesh F, Ye M, Salmi S, LaPointe MS, and Batlle D: Temporal profile of serum induced S phase entry and pRB phosphorylation in human skin fibroblasts. Kidney International 56:1282-1285, 1999.
[8]  LaPointe MS, Ye M, Bacallao R, and Batlle D: NHE-1 protein in vascular smooth muscle and lymphocytes from SHR and WKY rats. Hypertension 30(4):880-885, 1997.
[9]  Lurbe A, Fioretto P, Mauer M, LaPointe M, and Batlle D: Growth phenotype of cultured skin fibroblasts from IDDM patients with and without nephropathy and overactivity of the Na+/H+ antiporter. Kidney International 50:1684-1693, 1996.
[10]  Flores G, Ye M, LaPointe MS, and Batlle D: Ionic effects of Angiotensin II and their role in the activation of the Na+/H+ antiporter. Kidney International 49(suppl. 55):S122-S125, 1996.
[11]  Batlle D, Lurbe A, LaPointe MS, and Agrawal R: Na+/H+ antiporter, type I diabetes and hypertension. (editorial) Kidney: A Current Survey of World Literature. 4: 1-3, 1995.
[12]  LaPointe MS, Ye M, Moe O, Alpern R, and Batlle D: Na+/H+ antiporter (NHE-1 isoform) in vascular smooth muscle cells from the SHR. Kidney International 47: 78-87, 1995.
[13]  Batlle D, Redon J, Gutterman C, LaPointe MS, Saleh A, Rombola G,Ye M, Gomez L, and Sobero M: Acid-base status and intracellular pH regulation in lymphocytes from rats with genetic hypertension. J. Am. Soc. Nephrol. 5(5): S12-S22, 1994.
[14]  Batlle D, Peces R, LaPointe MS, Ye M, and Daugirdas JT: Cytosolic free calcium (iCa2+) in response to changes in intracellular pH in cultured vascular smooth muscle cells Am. J. Physiol. 264 (Cell physiol. 33): C932-C943, 1993.
[15]  Godnich MJ, LaPointe MS, and Batlle D: Free cytosolic calcium regulation via Na+/Ca2+ exchange in vascular smooth muscle cells. Ann. New York Acad. Sci. 639: 561-565, 1991.
[16]  Batlle DC, Godinich MJ, LaPointe MS, Munoz E, Carone F, and Mehring N: Extracellular Na+ dependency of free cytosolic Ca2+ regulation in aortic vascular smooth muscle cells. Am. J. Physiol. 261(Cell physiol. 30): C845-C856, 1991.
[17]  LaPointe MS, Jacobs WR, and Chan YL: Sodium and bicarbonate reabsorption in microperfused proximal tubules from the denervated rat kidney: relationship to cortical Na-K-ATPase activity. Chinese J. Physiol. 33 (3): 213-230, 1990.
[18]  Batlle D, Janns G, LaPointe M, Llibre J, and Saleh A: Cytosolic Calcium in T lymphocytes from the spontaneously hypertensive rat. Am. J. Hypertension 3: 343-348, 1990.
[19]  Batlle D, Gutterman C, Kelani T, Peces R and LaPointe MS: Effect of cyclosporin A on renal function and compensatory kidney growth in the uninephrectomized rat. Kidney International 37(1): 21-29, 1990.
[20]  Llibre J, LaPointe MS, and Batlle DC: Free cytosolic calcium in renal proximal tubules from the spontaneously hypertensive rat. Hypertension 12: 399-404, 1988.
[21]  Castaneda C and LaPointe MS: Development of Therapeutic Agents. "Gold Standard" Animal Models. Wiley Press, in press (accepted 2008).
[22]  LaPointe MS and Batlle DC: Intracellular pH and the Na+/H+ antiporter in smooth muscle. in: Contemporary Endocrinology (vol. 1) Endocrinology of the Vasculature. eds. James R. Sowers and Mary Walsh. Humana Press, Totowa, NJ, pp 301-323, 1996.
[23]  LaPointe MS, Ye M, and Batlle DC: Intracellular pH and Na+/H+ antiporter activity in cultured vascular smooth muscle cells from the spontaneously hypertensive rat. in: Acid-Base and Electrolyte Balance. Molecular, Cellular, and Clinical Aspects. eds. Natale Gaspare DeSanto and Giovambattista Campaso. Instituto Italiano per gli Studi Filosofici, Naples, Italy, pp 155-164, 1995.
[24]  LaPointe MS and Batlle D: Na+/H+ exchange and vascular smooth muscle cell proliferation. (review) Am. J. Med. Sci. 307 (suppl 1): S9-S16, 1994.