American Journal of Bioinformatics Research

American Journal of Bioinformatics Research publishes all the newest and distinguished research articles, reviews and letters in all areas of bioinformatics and computational biology. Each issue contains a series of timely, in-depth written articles by leaders in the field, covering a wide range of the integration of biology with computer and information science.


Shahenda El-Messery

Assistant Professor, Dept. of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura Univericity, Egypt

Research Areas

Pharmaceutical Organic Chemistry,Computational chemistry modern tecniques,Molecular Modeling,anticancer drugs,Antimicrobial Drugs

Publications: Journals

[1]  Somaia A.El-Mowafy, Khaled H.Abd El Galil, Shahenda M.El-Messery, and Mona I.Shaaban.Aspirin an Efficient Inhibitor of Quorum Sensing, Virulence and Toxins of Pseudomonas aeruginosa Microbial Microbial pathogenesis 74 (2014) 25-32
[2]    Sarah T.Al-Rashood, Ghada S.Hassan, Shahenda M.El-Messery, Mahmoud N.Nagi, El-Sayed E.Habib, Fatmah.A.Al-Omary, Hussein I.El-Subbagh Nonclassical antifolates, Part 6.2-(1,3,4-Thiadiazolylthio and 4-methyl-thiazol-ylthio)-quinazolin-4-ones as a new class of DHFR inhibitors: Synthesis, biological evaluation and molecular modeling study.Bioorganic Medicinal Chemistry Letters 24 (2014) 4557–4567.
[3]  Hussein I.El-Subbagh, Ghada S.Hassan, Shahenda M.El-Messery, Fatmah A.M.Al-Omary, Sarah T.Al-Rashood, Yasmin S.Abulfadl, Marwa I.Shabayek.Nonclassical antifolates, Part 5.Benzodiazepine analogues as a new class of DHFR inhibitors: Synthesis, antitumor testing and molecular modeling study.European Journal of Medicinal Chemistry 74 (2014) 234-245.
[4]  Ghada S.Hassan, Shahenda M.El-Messery, Fatmah A.M.Al-Omary, Sarah T.Al-Rashood, Marwa I.Shabayek,Yasmin S.Abulfadl, El-Sayed E.Habib, Walid Fayad, Khaled M.Mohamed,Salwa M.El-Hallouty,Bassem S.El-Menshawi,Hussein I.El-Subbagh "Nonclassical antifolates, Part 4.5-(2-Aminothiazol-4-yl)-4-phenyl-4H-1,2,4-triazole-3-thiols as a new class of DHFR inhibitors: Synthesis, biological evaluation and molecular modeling study." European Journal of Medicinal Chemistry.66 (2013) 135-145
[5]      Fatmah A.M.Al-Omary, Ghada S.Hassan, Shahenda M.El-Messery, Mahmoud N.Nagi, El-Sayed E.Habib, and Hussein I.El-Subbagh.Nonclassical antifolates, Part 3: Synthesis, biological evaluation and molecular modeling study of some new 2-heteroarylthio-quinazolin-4-ones. European Journal of Medicinal Chemistry 63, 33-45, (2013) http://dx.doi.org/10.1016/j.ejmech.2012.12.061
[6]  Ghada S.Hassan, Shahenda M.El-Messery, Fatmah A.M.Al-Omary, and Hussein I.El-Subbagh.Substituted thiazoles VII.Synthesis and antitumor activity of certain 2-(substitued-amino)-4-phenyl-thiazole analogues.Bioorganic Medicinal Chemistry Letters 22 6318–6323, (2012).
[7]  Shahenda M.El-Messery, Ghada S.Hassan, Fatmah A.M.Al-Omary, and Hussein I.El-Subbagh.Substituted thiazoles VI.Synthesis and antitumor activity of certain 2 substitued-aminothiazole analogues” European Journal of Medicinal Chemistry 54, 615-625, (2012).
[8]  Fatmah A.M.Al-Omary, Ghada S.Hassan, Shahenda M.El-Messery, Hussein I.El Subbagh: Substituted Thiazoles V.Synthesis and Antitumor Activity of Novel Thiazolo[2,3-b]quinazoline and Pyrido[4,3-d]thiazolo[3,2- a]pyrimidine Analogues.European Journal of Medicinal Chemistry ,47, 65-72 (2012),