American Journal of Bioinformatics Research

American Journal of Bioinformatics Research publishes all the newest and distinguished research articles, reviews and letters in all areas of bioinformatics and computational biology. Each issue contains a series of timely, in-depth written articles by leaders in the field, covering a wide range of the integration of biology with computer and information science.

Jian Li

Editorial Board Member of American Journal of Bioinformatics Research

Assistant Professor, Tulane University, USA

Research Areas

Statistical Genetics, Bioinformatics, Biostatistics, Human Genetics


2005Ph.DPh.D, genetics, North Carolina State University
2000M.S.M.S., biological sciences, Creighton University
1997B.S.B.S., biochemistry and molecular biology, Peking University


2005-2007Postdoctoral Fellow, Dept. of Molecular Biology and Genetics, Cornell University, Ithaca, NY
2007-2010Assistant Professor, Department of Informatic Medicine and Personalized Health, University of Missouri-Kansas City, Kansas City, MO
2010-presentAssistant Professor, Department of Biostatistics and Bioinformatics, Tulane University of Public Health and Tropical Medicine, New Orleans, LA
2010-presentAssistant Professor, Department of Biomedical Engineering, School of Science and Engineering, New Orleans, LA
2010-presentDirector, Section on Biostatistics and Bioinformatics, CBG, Tulane University School of Public Health and Tropical Medicine (SPHTM), New Orleans, LA

Publications: Conferences/Workshops/Symposiums/Journals/Books

[1]  Li J, Deng HW (2000) Estimation of parameters of deleterious mutations in partial selfing or partial outcrossing populations and in nonequilibrium populations. Genetics 154:1893-1906.
[2]  Tao Y, Zeng ZB, Li J, Hartl DL, Laurie CC (2003) Genetic dissection of hybrid incompatibilities between Drosophila simulans and D. mauritiana. II. Mapping hybrid male sterility loci on the third chromosome. Genetics 164:1399-1418.
[3]  Moehring AJ, Li J, Schug MD, Smith SG, deAngelis M, Mackay TF, Coyne JA (2004) Quantitative trait loci for sexual isolation between Drosophila simulans and D. mauritiana. Genetics 167:1265-1274.
[4]  Li J, Deng HW (2005) Estimation of the rate and effects of deleterious genomic mutations in finite populations with linkage disequilibrium. Heredity 95:59-68.
[5]  Li J, Wang SC, Zeng ZB (2006) Multiple interval mapping for ordinal traits. Genetics 173: 1649-1663.
[6]  Deng HW, Li J, Pfrender ME, Li JL, Deng HY (2006) Upper limit of the rate and per generation effects of deleterious genomic mutations. Genetical Research 88: 57-65.
[7]  Zhang JG, Li J, Deng HW (2008) Class-specific correlations of gene expressions: identification and their effects on clustering analyses. Am J Hum Genet. 83: 269-277.
[8]  Liu YZ, Wilson SG, Wang L, Liu XG, Guo YF, Li J, Deng HW (2008) Identification of PLCL1 Gene for Hip Bone Size Variation in Females in a Genome-Wide Association Study. PLoS ONE. 3: e3160.
[9]  Pei YF, Li J, Zhang L, Deng HW (2008) Analyses and Comparison of Accuracy of Different Genotype Imputation Methods. PLoS ONE. 3: e3551.
[10]  Yang RQ, Wang X, Li J, HW Deng (2009) Bayesian robust Analysis for Genetic Architecture of Quantitative Traits. Bioinformatics. 25: 1033-1039.
[11]  Guo YF, Li J, Bonham AJ, Wang YP, Deng HW (2009) Gains in power for exhaustive analyses of haplotypes using variable-sized sliding window strategy: a comparison of association-mapping strategies. Eur J Hum Genet. 17: 785-792.
[12]  Liu, YZ, Pei YF, Li J, Deng HW (2009) Genome-wide association analyses suggested a novel mechanism for smoking behavior regulated by IL15. Mol Psychiatry. 14: 668-680.
[13]  Lei SH, Tan LJ, Li J, Deng HW (2009) Genome-wide association study identifies two novel loci containing FLNB and SBF2 genes underlying stature variation. Hum Mol Genet. 18: 1661-1669.
[14]  Zhang JG, Li J, Deng HW (2009) Identifying gene interaction enrichment for gene expression data. PLoS ONE. 4: e8064.
[15]  Zhang L, Pei YF, Li J, Papasian CJ, Deng HW (2009) Univariate/multivariate genome-wide association scans using data from families and unrelated samples. PLoS One. 4: e6502.
[16]  Zhang L, Li J, Pei YF, Liu Y, Deng HW (2009) Tests of association for quantitative traits in nuclear families using principal components to correct for population stratification. Ann Hum Genet. 73: 601-613.
[17]  Zhang L, Bonham AJ, Li J, Pei YF, Chen J, Papasian CJ, Deng HW (2009) Family-based bivariate association tests for quantitative traits. PLoS One. 4: e8133.
[18]  Li J, Yang TL, Deng HW (2009) Whole genome distribution and ethnic differentiation of copy number variation in Caucasian and Asian populations. PLoS One. 4: e7958.
[19]  Guo YF, Li J, Chen Y, Zhang LS, Deng HW (2009) A new permutation strategy of pathway-based approach for genome-wide association study. BMC Bioinformatics. 10: 429.
[20]  DE Moor MH, Liu YJ, Boomsma DI, Li J, Deng HW (2009) Genome-Wide Association Study of Exercise Behavior in Dutch and American Adults. Med Sci Sports Exerc. In press.
[21]  Pei YF, Zhang L, Li J, Deng HW (2010) Analyses and comparison of imputation-based association methods. PLoS One. 5: e10827.
[22]  Zhao LJ, Li J, (2010) Genome-wide association study for femoral neck bone geometry. J Bone Miner Res. 25: 320-329.
[23]  Lin Y, Li J,(2011) Comparative Studies of de novo Assembly Tools for Next-generation Sequencing Technologies. Bioinformatics. 27(12): 1093