International Journal of Optoelectronic Engineering

International Journal of Optoelectronic Engineering is a peer-reviewed journal mainly publishing the innovative academic thesis, the research note, the research letter in the field of optics and electronics. The journal aims at providing an emerging platform for publication of original research so that the engineers can exchange and share professional, technical and academic knowledge on any aspect of optoelectronic engineering discipline.

Nanguang Chen

Editorial Board Member of International Journal of Optoelectronic Engineering

Associate Professor, National University of Singapore, Singapore

Research Areas

Biophotonics, Biomedical Electronics, Optical Imaging

Education

2000Ph.DDepartmentofElectricalEngineering, TsinghuaUniversity
1994M. SDepartmentofPhysics, PekingUniversity
1988B. SDepartmentofElectricalEngineering, HunanUniversity

Experience

2004-presentAssistant Professor, Division of Bioengineering, Faculty of Engineering, National University of Singapore
2002-2004Assistant Research Professor, Department of Electrical and Computer Engineering, University of Connecticut
2000-2001Postdoctoral Fellow, Department of Electrical and Computer Engineering, University of Connecticut
1994-1997Lecturer, Department of Physics, Hunan Normal University
1988-1991Instrumentation Engineer, Hunan Detergent Factory

Academic Achievement

2004 Young Investigator Award, Office of Life Science/National University of Singapore
2001 Postdoctoral Training Award, Department of Defense Breast Cancer Research Program of the US Army Medical Research and Materiel Command
2001 Excellent Ph. D. Dissertation Award, Tsinghua University

Publications: Journals

[1]  K. Mehta and N. G. Chen, "Plasmonic chiral contrast agents for optical coherence tomography, " Optics Express, accepted.
[2]  G. Gao, S. P. Chong, C. J. R. Sheppard, N. G. Chen, "Considerations of apertureconfiguration in focal modulation microscopy from the standpoint of modulationdepth, " Journal of the Optical Society of America A 28 (4), 496-501 (2011).
[3]  L. Chen and N. G. Chen, "Optimization of Source and Detector Configurations Basedon Cramer-Rao Lower Bound Analysis, " Journal of Biomedical Optics 16 (3), 035001(2011).
[4]  K. Si, W. Gong, N. G. Chen, and C. J. R. Sheppard, "Enhanced background rejection in thick tissue using focal modulation microscopy with quadrant apertures, " Optics Communications 284 (5), 1475-1480 (2011).
[5]  S. P. Chong, C. H. Wong, K. F. Wong, C. J. R. Sheppard, and N. G. Chen, "High-speed focal modulation microscopy using acousto-optical modulators, " Biomedical Optics Express 1 (3), 1026-1033 (2010).
[6]  Q. Zhang, L. Chen, and N. G. Chen, "Pseudo-random single photon counting: a high-speed implementation, " Biomedical Optics Express 1 (1), 41-46 (2010).
[7]  S. P. Chong, C. H. Wong, C. J. R. Sheppard, and N. G. Chen, "Focal Modulation Microscopy: A Theoretical Study, " Optics Letters 35 (11), 1804-1806 (2010).
[8]  W. Gong1, K. Si, N. G. Chen, and C. J. R. Sheppard, "Focal modulation microscopy with annular apertures: A numerical study, " Journal of Biophotonics 3 (7), 476-484 (2010).
[9]  W. Mo and N. G. Chen, "Design of Advanced Time-Domain Diffuse Optical Tomography System, " IEEE Journal of Selected Topics in Quantum Electronics 16 (3), 581-587 (2010).
[10]  Y. Xu, J. Singh, and N. G. Chen, "Large rotation angle micromirror based on hypocycloidal electrothermal actuators, " Electronics Letters 46 (10) 704-706 (2010).
[11]  H. T. Tian, F. Shakith, H. W. Soon, Q. Zhang, C. Zhang, Y. Ha and N. G. Chen, "Ultra Storage Efficient Time Digitizer for Pseudo Random Single Photon Counter Implemented on Field Programmable Gate Array, " IEEE Transactions on Biomedical Circuits and Systems 4 (1), 1-10 (2010).
[12]  K. Agarwa, L. Chen, N. G. Chen, and X. Chen, "Multistage Inversion Algorithm for Biological Tissue Imaging, " Journal of Biomedical Optics 15 (1), 016007 (2010).
[13]  Y. Xu, M. F. Wang, C. S. Premachandran, K. W. S. Chen, N. G. Chen and M. Olivo, "Platinum microheater integrated silicon optical bench assembly for endoscopic optical
[14]  coherence tomography, " Journal of Micromechanics and Microengineering 20 (2010), 015008 (8pp).
[15]  K. Si, W. Gong, N. G. Chen, C. J. R. Sheppard, "Edge enhancement for in-phase focal modulation microscope, " Applied Optics 48 (32), 6290-6295 (2009).
[16]  W. Gong, K. Si, N. G. Chen, C. J. R. Sheppard, "Improved spatial resolution in fluorescence focal modulation microscopy, " Optics letters 34 (22), 3508-3510 (2009).
[17]  W. Mo, T. Chan, L. Chen, and N. G. Chen, "Quantitative characterization of optical and physiological parameters in normal breasts using time-resolved spectroscopy: in-vivo results of 19 Singapore women, " Journal Biomedical Optics 14 (6), 064004 (2009).
[18]  C. H. Wong, S. P. Chong, C. J. R. Sheppard, and N. G. Chen, "Simple spatial phase modulator for focal modulation microscopy, " Applied Optics 48 (17), 3238-3243(2009).
[19]  E. L. Lim, J. Teng, S. S. Ang; J. Dong, S. Chua, K. Shanmugasundaram, and N. G. Chen, "The near-diffraction limited operation of submicron-ridge laser arrays, " IEEE Journal of Quantum Electronics 45 (8), 893-903 (2009).
[20]  C. S. Premachandran, A. Khairyanto, K. Chen, J. Singh, J. Teo, Y. XU, N. G. Chen, C. J. R. Sheppard, and M. Olive, "Design, Fabrication, and Assembly of an Optical
[21]  Biosensor Probe Package for OCT (Optical Coherence Tomography) Application, " Y. Xu, J. Singh, S. Thevapriya and N. G. Chen, "Two-axis gimbal-less electrothermal
[22]  micromirror for large angle circumferential scanning, " IEEE Journal of Selected Topics in Quantum Electronics 15 (5), 1432-1438 (2009).IEEE Transactions on Advanced Packaging 32 (2), 417-422 (2009).
[23]  J. Cheng, Y. Zhang, P. Gopalakrishnakone and N. G. Chen, "Use of the Upside-Down Method to Prepare Porous Polymer Films with Tunable Surface Pore Sizes, " Langmuir 25 (1), 51–54 (2009).
[24]  N. G. Chen, C. H. Wong and C. J. R. Sheppard, "Focal Modulation Microscopy, " Optics Express 16 (23), 18764-18769 (2008).
[25]  Y. Xu, J. Singh, C. S. Premachandran, A. Khairyanto, K. W. S. Chen, N. G. Chen, C. J. R. Sheppard and M. Olivo, "Design and development of a 3D scanning MEMS OCT probe using a novel SiOB package assembly, " Journal of Micromechanics and Microengineering 18 125005 (2008).
[26]  W. Mo and N. G. Chen, "Fast time domain diffuse optical tomography using pseudorandom bit sequences, " Optics Express 16 (18), 13643-13650 (2008).
[27]  Q. Zhang, H. W. Soon, H. T. Tian, S. D. Fernando, Y. Ha and N. G. Chen, "Pseudo Random Single Photon Counting for Time Resolved Optical Measurement, " Optics Express 16 (17), 13233-13239 (2008).
[28]  L. LIU, F. Diaz, L. Wang, B. Loiseaux, J. Huignard, C. J. R. SHEPPARD and N. G. Chen, "Super-resolution along extended depth of focus with binary-phase filters for
[29]  Gaussian beam". Journal of the Optical Society of America A-Optics Image Science and Vision 25 (8), 2095-2101 (2008).
[30]  J. Singh, J. H. S. Teo, Y. Xu, C. S. Premachandran, N. G. Chen, R. Kotlanka, M. Olive and C. J. R. SHEPPARD, "A two axes scanning SOI MEMS micromirror for
[31]  endoscopic bioimaging". Journal of Micromechanics and Microengineering 18, 025001(2008).
[32]  X. Song, D. Wang, N. G. Chen, J. Bai, and H. Wang, "Reconstruction for free-space fluorescence tomography using a novel hybrid adaptive finite element algorithm, " Optics Express 15 (26), 18300-18317 (2007).
[33]  L. Liu, C. J. R. Sheppard, and N. G. Chen, "Double-reflection polygon mirror for high-speed optical coherence microscopy, " Optics Letters 32, 3528-3530 (2007).
[34]  L. Liu, C. Liu, C. H. Wong, C. J. R. Sheppard, and N. G. Chen, "Binary-phase spatial filter for real-time swept source optical coherence microscopy, " Optics Letters 32, 2375-2377 (2007).
[35]  Y. Xu, J. Singh, C. J. R. Sheppard, and N. G. Chen, "Ultra long high resolution beam by multi-zone rotationally symmetrical complex pupil filter, " Optics Express 15 (10), 6409-6413 (2007)
[36]  N. G. Chen, "Controlled Monte Carlo method for light propagation in tissue of semi-infinite geometry, " Applied Optics 46 (10), 1597-1603 (2007).
[37]  C. Liu, N. G. Chen, and C. Sheppard, "Nano-illumination based on self-imaging inside the sub-wavelength metallic slit, " Applied Physics Letters 90 (1), Art. No. 011501 (2007).
[38]  L. Liu and N. G. Chen, "Double-pass rotary mirror array for fast scanning optical delay line, " Applied Optics 45 (21), 5426-5431 (2006).
[39]  Q. Zhu, E. B. Cronin, A. A. Currier, H. S. Vine, M. Huang, N. G. Chen, C. Xu, "Benign versus malignant breast masses: optical differentiation with US-guided optical Imaging reconstruction, " Radiology 237 (1), 57-66 (2005).
[40]  J. Bai, T. X. Gao, Y. Kui, and N. G. Chen, "Locating inhomogeneities in tissue by using the most probable diffuse path of light, " Journal of Biomedical Optics 10 (2), Art No. 204024 (2005).
[41]  Q. Zhu, S. H. Kurtzman, P. Hegde, S. Tannenbaum, M. Kane, M. Huang, N. G. Chen, B. Jagjivan, K. Zarfos, "Utilizing optical tomography with ultrasound localization to
[42]  image heterogeneous hemoglobin distribution in large breast cancers, " Neoplasia 7 (3), 263-270 (2005).
[43]  N. G. Chen, M. Huang, H. Xia, D. Piao, E. Cronin, and Q. Zhu, "Portable near infrared diffusive light imager for breast cancer detection, " Journal of Biomedical Optics 9 (3), 504-510 (2004).
[44]  B. H. Yuan, N. G. Chen, and Q. Zhu, "Absorption and Emission Properties of Indocyanine Green in Intralipid Solution, " Journal of Biomedical Optics 9 (3), 497-503(2004).
[45]  R. C. Leif, M. C. Becker, A. J. Bromm, N. G. Chen, A. Cowan, L M. Vallarino, S. Yang, R. M. Zucker, "One and two photon excitation of cells and molecules labeled
[46]  with a europium(III)macrocycle (Quantum Dye (R)) under Lanthanide Enhanced Luminescence (LEL), " Cytometry 59A (1): 74-74 MAY 2004.
[47]  N. G. Chen and Q. Zhu, "Time-resolved diffusive optical tomography using pseudo-random sequences, " Optics Express 11 (25), 3445-3454 (2003).
[48]  Q. Zhu, M. Huang, N. G. Chen, K. Zarfos, B. Jagjivan, M. Kane, S. H. Kurtzman, "Ultrasound-guided optical tomographic imaging of malignant and benign breast lesions: initial clinical results of 19 cases, " Neoplasia 5 (5), 379-388 (2003).
[49]  M. Huang, T. Xie, N. G. Chen, and Q. Zhu, "NIR imaging reconstruction with ultrasound localization, " Applied Optics 42 (19), 4102-4114 (2003).
[50]  Q. Zhu, N. G. Chen, and S. Kurtzman, "Imaging tumor angiogenesis using combined near infrared diffusive light and ultrasound, " Optics Letters 28 (5), 337-339 (2003).
[51]  N. G. Chen, and Q. Zhu, "Time-resolved optical measurements with spread spectrum excitations, " Optics Letters 27 (20), 1806-1808 (2002).
[52]  N. G. Chen, and Q. Zhu, "Rotary mirror array for high speed optical coherence tomography, " Optics Letters 27 (8), 607-609 (2002).
[53]  N. G. Chen and Q. Zhu, "Characterization of small absorbers inside turbid media, " Optics Letters 27 (4), 252-254 (2002).
[54]  Q. Zhu, N. G. Chen, P. Y. Guo, S. K. Yan, and D. Q. Piao, "Near infrared diffusive light imaging with ultrasound localization, " OSA Optics and Photonics News, Optics in 2001, 12:31, December 2001
[55]  N. G. Chen, P. Guo, S. Yan, D. Piao, and Q. Zhu, "Simultaneous near infrared diffusive light and ultrasound imaging, " Applied Optics 40 (34), 6367-6280 (2001).
[56]  Q. Zhu, N. G. Chen, X. H. Ding, D. Piao, and P. Guo, "Design of near infrared imaging probe with the assistance of ultrasound localization, " Applied Optics 40 (19), 3288-3303 (2001).
[57]  H. Xu, Y. Zhang, N. G. Chen, and J. Bai, "NIR diffusive optical imager for breast cancer detection, " Chinese Journal of Scientific Instrument 21 (5), 44-47 (2000).
[58]  N. G. Chen and J. Bai, "Estimation of Quasi-Straight-Forward Propagating Light in Tissue, " Physics in Medicine & Biology. 44 (7), 1669-1676, (1999).
[59]  N. G. Chen and J. Bai, "Monte-Carlo Approach to Modeling of Boundary Conditions for the Diffusion Equation, " Physical Review Letters 80 (24), 5321-5324 (1998).
[60]  N. G. Chen, and K. T. Chao, "The quark axial-vector coupling and heavy meson decays, " Physics Letters B 345 (1), 67-73 (1995).