American Journal of Organic Chemistry

American Journal of Organic Chemistry is an open-access, peer-reviewed journal describing the design of, synthetic approaches to, and characterization of new molecules with applications in organometallics, medicinal and heterocyclic chemistry, green chemistry, photochemistry, materials science, nanotechnology, and catalysis. Articles considered for publication include: original scientific research articles, review type articles and communications.


Cosimo Gianluca Fortuna

Editorial Board Member of American Journal of Organic Chemistry

Assistant Professor, Dipartimento di Scienze Chimiche, University of Catania, Italy

Research Areas

Organic chemistry, Molecular modelling

Education

2004-2006Post-doctoralCatania University
2004Ph.DCatania University
2000BachlorDepartment of Chemistry, University of Catania

Experience

2010-2011Taught Organic chemistry course 2.
2009-2010Taught Organic chemistry course 1.
2008-2010Taught "Degradazione di materiali organici nei Beni Culturali"
2007-2009Taught "Elementi di Chimica organica e laboratorio"
2006-2009Taught "Chimica Organica per i beni culturali e protettivi consolidanti organici"

Membership

Member of Società Chimica Italiana and of the QSAR Society
Member of the directive committee of the Società Chimica Italiana (SCI) young group(2006-2009)
Member of the directive committee of the Sicilian section of the SCI(2006-present)

Publications: Journals

[1]  S, Scirè, G. Musumarra, D. F. Condorelli, C. G. Fortuna, "Potentialites of the PLS approach in genome-scale cancer pharmacology research", Clin. Cancer Res., 7, 11 (2001)
[2]  M. Fichera, C. G. Fortuna, G. Impallomeni, G. Musumarra, "Studies on the Interactions of the new 2,6-Bis[2-(heteroaryl)vinyl]-1-methylpyridinium Cations with the Decamer d(CGTACGTACG)2", Eur. J. Org. Chem., 145-150 (2002).
[3]  V. Barresi, D. F. Condorelli, C. G. Fortuna, G. Musumarra, "In Vitro Antitumor Activities of 2,6-di-[2-(Heteroaryl)vinyl]pyridines and Pyridiniums", Bioorg. Med. Chem., 10, 2899-2904 (2002) .
[4]  F. P. Ballistreri, C. G. Fortuna, G. Musumarra, D. Pavone, S. Scirè, "Principal Properties (PPs) as solvent descriptors for multivariate optimisation in organic synthesis: specific PPs for ethers", Arkivoc 2002, part(xi), 54-64 or at http://www.arkat-usa.org/ark/journal/2002/I11_Spinelli/MS-568H/568H.asp
[5]  F. P. Ballistreri, V. Barresi, G. Consiglio, C. G. Fortuna, M.L. Longo, G. Musumarra, " Synthesis spectroscopic characterization and in vitro antitumor activity of new trans 1-heteroaryl-2-(1-methylpyridinium-2-yl) ethylenes", Arkivoc 2003, part(i), 105-117 or at http://www.arkat-usa.org/ark/journal/2003/General/Part(i)_index.htm.
[6]  G. Cruciani, P. Benedetti, G. Caltabiano, D. F. Condorelli, C. G. Fortuna and G. Musumarra, "Structure-based Rationalization of Antitumor Drugs Mechanism of Action by a MIF Approach", Eur. J. Med. Chem., 39, 281-285 (2004).
[7]  G. Musumarra, V. Barresi, D. F. Condorelli, C. G. Fortuna, S. Scirè, "Potentialites of multivariate approaches in genome based cancer research: identification of candidate genes for new diagnostics by PLS-discriminant analysis", J.Chemometrics, 18, 125-132 (2004).
[8]  F. P. Ballistreri, V. Barresi, P. Benedetti, G. Caltabiano, C. G. Fortuna, M. L. Longo, G. Musumarra, "Design, Synthesis and in Vitro Antitumor Activity of New trans 1-Heteroaryl-2-(1,3-dimethylimidazolium-2-yl)ethylenes", Bioorg. Med. Chem., 12, 1689-1695 (2004).
[9]  G. Musumarra, V. Barresi, D. F. Condorelli, C. G. Fortuna, S. Scirè, " Genome-based identification of diagnostic molecular markers for human lung carcinomas by PLS-DA", Computational Biology and Chemistry, 29, 183-195 (2005).
[10]  E. Marri, U. Mazzucato, C. G. Fortuna, G. Musumarra, A. Spalletti "Photobehaviour of some trans-1-heteroaryl-2-(1-methylpyridinium-2-yl)ethene iodides (free and complexed with DNA), Journal of Photochemistry and Photobiology. A: Chem., 179, 314-319 (2006).
[11]  V. Barresi, C. G. Fortuna, R. Garozzo, G. Musumarra, S. Scirè, D. F. Condorelli "Identification of genes involved in the sensitivity to antitumour drug 17-allylamino,17-demethoxygeldanamycin (17AAG)", Molecular Biosystems, 2, 231-239 (2006).
[12]  F. Broccolo, G. Cainelli, G. Caltabiano, C. E. A. Cocuzza, C. G. Fortuna, P. Galletti, D. Giacobini, G. Musumarra, R. Musumeci, A. Quintavalla "Design, Synthesis and Biological Evaluation of 4-Alkyliden-beta lactams: New Products with a promising Antibiotic Activity Against Resistant Bacteria", Journal of Medicinal Chemistry, 49, 2804-2811 (2006).
[13]  C. G. Fortuna, G. Musumarra, M. Nardi, A. Procopio, G. Sindona, S. Scirè " Principal Properties (PPs) of lantanide triflates as Lewis-acid catalysts", J. Chemometrics, 20, 418-424 (2006).
[14]  G. Musumarra, A. Salinaro-Trovato, S. Scirè, A. Foti, V. Barresi, C. G. Fortuna, G. Strazzulla, D. F. Condorelli, "Identification of genes involved in radiation-induced G1 arrest", J. Chemometrics, 21, 398-405 (2007).
[15]  C. G. Fortuna, V. Barresi, G. Berellini, G. Musumarra, "Design and synthesis of trans 2-(furan-2-yl)vinyl heteroaromatic iodides with antitumour activity.", Bioorg. Med. Chem., 16, 4150-4159 (2008).
[16]  C. G. Fortuna, V. Barresi, N. Musso, G. Musumarra, "Synthesis and applications of new trans 1-indolyl-2-(1-methyl pyridinium and quinolinium-2-yl)ethylenes", Arkivoc 2009, part(viii), 122-129.
[17]  F. P. Ballistreri, C. G. Fortuna, A. Pappalardo, G. A. Tomaselli, R.M. Toscano, " Oxidation of organic silfide by a vanadium(5+) oxo-monoperoxo-picolinate complex: Kinetics and mechanism", J. Mol. Cat. A, 308, 56-60 (2009).
[18]  C. G. Molteni, G. Cazzaniga, D. F. Condorelli, C. G. Fortuna, A. Biondi, G. Musumarra, "Successful application of OPLS-DA for the discrimination of wild-type and mutated cells in acute lymphoblastic leukaemia", QSAR & Comb. Sci., 28, 822-828 (2009) . 19. C. G. Fortuna, V. Barresi, G. Musumarra, "Design, synthesis and biological evaluation of trans 2-(thiophen-2-yl)vinyl heteroaromatic iodides" Bioorg. Med. Chem., 18, 4516-4523 (2010).
[19]  C. G. Fortuna, U. Mazzucato, G. Musumarra, D. Pannacci, A. Spalletti, "Photochemistry and DNA-affinity of some stilbene and distyrylbenzene analogues containing pyridinium and imidazolium iodides", Journal of Photochemistry and Photobiology. A: Chem., 216, 66-72 (2010)
[20]  Musumarra G, Condorelli D. F, Fortuna C. G. "OPLS-DA as a suitable method for selecting a set of gene transcripts discriminating RAS-and PTPN11-mutated cells in acute lymphoblastic leukaemia." Journal of Combinatorial Chemistry, 14; 36-46 (2011).
[21]  Fortuna C., Bonaccorso C, Qamarb F, Anu A, Ledoux I, Musumarra G "Synthesis and NLO properties of new trans 2-(thiophen-2-yl)vinyl heteroaromatic iodides." Organic & Biomolecular Chemistry, 9(5), 1608-1613 (2011).
[22]  Alessandra Mazzoli, Benedetta Carlotti, Cosimo G. Fortuna and Anna Spalletti "Photobehaviour and DNA interaction of styrylquinolinium salts bearing thiophene substituents" Photochem. Photobiol. Sci., 10, 973-979 (2011).
[23]  Alessandra Mazzoli, Benedetta Carlotti, Carmela Bonaccorso, Cosimo G. Fortuna, Ugo Mazzucato, Giorgia Miolo, Anna Spalletti "Photochemistry and DNA-affinity of some pyrimidine-substituted styryl-azinium iodides" Photochem. Photobiol. Sci., accepted (2011).