Nanoscience and Nanotechnology

Nanoscience and Nanotechnology is an international and multidisciplinary peer-reviewed journal covering fundamental and applied research in all disciplines of science, engineering and medicine.

CHITTARANJAN PATRA

Editorial Board Member of Nanoscience and Nanotechnology

Research Scientist, Department of Chemical Biology, Indian Institute of Chemical Technology, India

Research Areas

Nanomaterials, Cancer Nanotechnology, Drug Delivery, Angiogenesis

Education

2003Ph.D.Chemistry, NCL (University of Pune)
1997M.Sc.Organic Chemistry, The University of Burdwan
1995B.Sc.Chem. (Hons.), The University of Burdwan (Gold Medalist)

Experience

2010-present Ramanujan Fellow Scientist, IICT, Hyderabad, AP, India
2011-May Visiting Scientist, Mayo Clinic, Rochester, USA
2008-2010 Assistant Professor, Mayo Clinic, Rochester, USA
2007-2008 Senior Research Fellow, Mayo Clinic, Rochester, USA
2004-2007 Postdoctoral Research Fellow, Mayo Clinic, Rochester, USA
2003-2004 Postdoctoral Research Fellow, Bar-Ilan University, Israel
2001-2003 Senior Research Fellowship (CSIR New Delhi)
1998-2001 Junior Research Fellowship (CSIR New Delhi)

Academic Achievement

2011, Visiting Scientist at Mayo Clinic, Rochester, MN, USA.
2010, Received prestigious Ramanujan Fellowship from Department of Science &
1998, " Dr. Mrigendranath Ghosh Gold Medal" from The University of Burdwan, West Bengal, India
2010, Received ‘Michael A. O’Connor Travel Award ’
2008, Young Investigator Award
1998-2001, Junior Research Fellowship
2001-2003, Senior Research Fellowship
2003-2004, Postdotoral Fellowship
2004-2007, Postdoctoral Research Fellowship
2007-2008, Senior Postdoctoral Research Fellowship

Membership

2007, Member, American Chemical Society (ACS)
2008, Associate Member, American Association for Cancer Research (AACR)
2008, Member, American Association for the Advancement of Sci ence (AAAS)

Publications: Conferences/Workshops/Symposiums/Journals/Books

[1]  Patra CR, Rupasinghe CN, Bhattacharya S, Wang E, Spaller MR, Mukhopadhyay D. Chemically-Modified Peptides Targeting the PDZ Domain of GIPC as a Therapeutic Approach for Cancer. ACS Chemical Biology (2012) DOI: 10.1021/cb200536r (ISI 2010 Impact Factor 5.7).
[2]  Patil NT, Lakshmi PGVV, Sridhar B, Patra S, Pal Bhadra M and Patra CR*. Novel Linearly and Angularly Fused Quinazolinones: Synthesis via Gold-Catalyzed Cascade Reactions and their Anticancer Activities. European Journal of Organic Chemistry, 2012 (in press) DOI: 10.1002/ejoc.201101822 corresponding author. (ISI 2010 Impact Factor 3.206).
[3]  *Patra CR, Kim J-H, Pramanik K, d'Uscio LV, Patra S, Katusic ZS, Ramchandran R, Strano MS, Mukhopadhyay D. Reactive Oxygen Species Driven Angiogenesis by Inorganic Nanorods. Nano Letters, 11(11), 4932–4938 (2011), DOI: 10.1021/nl2028766 (corresponding author). (ISI 2010 Impact Factor 12.186).
[4]  Kim J-H, Patra CR, Arkalgud JR, Boghossian AA, Zhang J, Jae-Hee Han1, Nigel F. Reuel1, Ahn J-H, Mukhopadhyay D and Strano MS. Single Molecule Detection of H2O2 Mediating Angiogenic Redox Signaling on Fluorescent Single-Walled Carbon Nanotube Array. ACS Nano, 5 (10), pp 7848–7857, 2011; DOI: 10.1021/nn201904t. (ISI 2010 Impact Factor 9.9).
[5]  Srinivas P, Patra CR, Bhattacharya and Mukhopadhyay D. Gold nanoparticle can quench the ROS generating capacity when conjugated with naphthaquinones. International Journal of Nanomedicine, 6, 2113–2122, 2011. Journal Impact Factor 4.976.
[6]  Patra CR, Wang, L, Lau JS, Cao Y, Bhattacharya S, Dutta S, Nandy D, Wang E, Rupasinghe CN, Vohra P, Speller MR, and Mukhopadhyay D. The RGS-GAIPinteracting protein Controls Breast Cancer Progression. Molecular Cancer Research 8, 1591-1600, 2010 (Published on October 27, 2010; doi: 10.1158/1541-7786.MCR-10- 0209) (ISI 2010 Impact Factor 4.373). [*First three authors have equal contribution].
[7]  Das A, Mukherjee P, Singla SK, Guturu P, Frost M C, Mukhopadhyay D, Shah VH, and Patra CR. Fabrication and characterization of inorganic gold and silica nanoparticle mediated drug delivery system for nitric oxide. Nanotechnology 21 (2010) 305102. 2010(ISI 2010 Impact Factor 3.664). (*Corresponding Author).
[8]  Patra CR, Jing Y, Xu Y-H, Bhattacharya R, Mukhopadhyay D, Glockner JF, Wang J-P, Mukherjee P. A core-shell nanomaterial with endogenous therapeutic and diagnostic functions. Cancer Nanotechnology 2010 (doi: 10.1007/s12645-010-0002-4).
[9]  Patra CR, Bhattacharya R, Mukherjee P. Fabrication and functional characterization of goldnanoconjugates for potential application in ovarian cancer. J. Mater. Chem. 20 (4), 547-554 (2010). (ISI 2010 Impact Factor 5.099)
[10]  Patra CR*, Abdel Moneim S, Wang E, Dutta S, Eshed M, Mukherjee P, Patra S, Gedanken A, Shah V, Mukherjee P and Mukhopadhyay D. In Vivo Toxicity Studies Europium Hydroxide in Mice. Toxicology and Applied Pharmacology 240, 88- 98(2009) doi:10.1016/j.taap.2009.07.009 (ISI 2010 Impact Factor 3.993) (*Corresponding Author).
[11]  Grinberg O, Gedanken A, Patra CR, Patra S, Mukherjee P and Mukhopadhyay D. Sonochemically-prepared BSA microspheres containing Gemcitabine, and their potential application in renal cancer therapeutics. Acta Biomaterialia (2009) doi:10.1016/j.actbio.2009.05.003. (ISI 2010 Impact Factor 4.822)
[12]  Curley SA, Cherukuri P, Briggs K, Patra CR, Upton M, Dolson E, Mukherjee P. Noninvasive Radiofrequency Field-Induced Hyperthermic Cytotoxicity in Human Cancer Cells Using Cetuximab-Targeted Gold Nanoparticles. Journal of Experimental Therapeutics and Oncology, 7 (4), 313-326(2008).
[13]  Patra CR, Cao S, Safgren S, Bhattacharya R, Ames MM, Shah V, Reid JM, Mukherjee P. Intracellular fate of a targeted delivery system. J. Biomedical Nanotechnology, 4, 508-514 (2008). ISI 2010Impact Factor 2.626.
[14]  Patra CR, Verma R, Kumar S, Greipp PR, Mukhopadhyay D, Mukherjee P. Fabrication of Gold Nanoparticle for Potential Application in Multiple Myeloma. J. Biomedical Nanotechnology, 4; 499-507 (2008). ISI 2010Impact Factor 2.626.
[15]  Bhattacharya R, Sinha S, Yang S-P, Patra CR, Dutta S, Wang E, Mukhopadhyay D. The neurotransmitter dopamine modulates vascular permeability in the endothelium. Journal of Molecular Signaling, 3:14 (28 July 2008) (impact factor 2.80).
[16]  Gedanken, A. Ben David Makhluf, S, Arnon R., Patra CR, Mukhopadhyay D and Breitbart H. Labeling of sperm cells via the spontaneous penetration of Eu+3 ions as nanoparticles complexed with PVA or PVP. The Journal of Physical Chemistry C, 112 (33), 12801-12807(2008). ISI 2010 Impact Factor 4.52.
[17]  Patra C R, Bhattacharya R, Wang E, Katarya A, Lau J S, Dutta S, Muders M, Wang S, Buhro S, Safgren S, Yaszemski M J, Reid J, Ames M, Mukherjee P, Mukhopadhyay D. Targeted delivery of gemcitabine to pancreatic tumor using cetuximab as a targeting agent. Cancer Research 68(6), 1970-1978 (March 15, 2008). (ISI 2010 Impact Factor 8.234). Commentary: An article entitled "Nanomedicine: Treating Disease with Gold Bullets and Nanorods" has been published in Discovery's Edge, Mayo Clinic's online research magazine, based on our nanorods induced angiogenesis and cancer nanotechnology research.
[18]  Gannon CJ, Patra CR, Bhattacharya R, Mukherjee P and Curley SA. Intracellular Gold Nanoparticles Enhance Non-Invasive Radiofrequency Thermal Destruction of Human Gastrointestinal Cancer Cells. Journal of Nanobiotechnolgy 6:2 (2008) (Journal impact factor 4.59).
[19]  Patra CR, Bhattacharya R, Patra S, Vlahakis NE, Gabashvili A, Koltypin Y, Gedanken A, Mukherjee P and Mukhopadhyay D. Proangiogenic properties of europium(III) hydroxide nanorods. Advanced Materials, 20(4), 753-756(2008). (ISI 2010 Impact Factor 10.857)
[20]  Patra CR, Bhattacharya R, Patra S, Basu S, Mukherjee P and Mukhopadhyay D. Lanthanide Phosphate nanorods used as inorganic fluorescent label in cell biology research. Clinical Chemistry 53(11)- 2029-2031(2007). (ISI 2010 Impact Factor 6.886)
[21]  Patra CR*, Bhattacharya R*, Earl A, Wang S, Katarya A, Lu L, Kizhakkedathu JN, Yaszemski MJ, Greipp PR, Mukhopadhyay D and Mukherjee P. Attaching folic acid on gold nanoparticles using noncovalent interaction via different polyethylene glycol backbones and targeting of cancer cells. Nanomedicine: Nanotechnology, Biology and Medicine: 3(3), 224-238(2007). ISI 2010 Impact Factor 4.882. [*Both the authors have equal contribution].
[22]  Mukherjee P, Bhattacharya R, Bone N, Lee YK, Patra CR, Wang S, Lu L, Yaszemski MJ, Kay NE and Mukhopadhyay D. Potential Therapeutic Application of Gold Nanoparticles in B-chronic Lymphocytic Leukemia (B-CLL): Enhancing apoptosis. Journal of Nanobiotechnolgy. 5:3, 2007(Journal impact factor 4.59).
[23]  Bhattacharya R, Patra CR, Verma R, Kumar S, Greipp PR and Mukherjee P. Gold Nanoparticles inhibit proliferation of Multiple Myeloma cells. Advanced Materials 2007, 19(5), 711-716. (ISI 2010 Impact Factor 10.857)
[24]  Patra CR, Odani A, Pol VG, Aurbach D and Gedanken A. Microwave–assisted Synthesis of Tin Sulfide Nanoflakes and their Electrochemical Performance as Liinserting Materials. Journal of Solid State Electrochemistry, 2007, 11(2)186-194. (ISI 2010 Impact Factor = 2.234)
[25]  Patra CR, Bhattacharya R, Patra S, Basu S, Mukherjee P and Mukhopadhyay D. Inorganic Phosphate Nanorods are a Novel Fluorescent Label in Cell Biology. Journal of Nanobiotechnolgy 2006, 4:11 (journal impact factor 4.59).
[26]  Bhattacharya R, Patra CR, Wang S, Lu L, Yaszemski MJ, Mukhopadhyay D and Mukherjee P. Protein can act as unique template to assemble gold nanoparticles in a linear fashion. Technical Proceedings of the 2006 NSTI Nanotechnology Conference and Trade Show, Volume 2, Chapter 10: Polymer Nanocomposites, Page 833-836.
[27]  Bhattacharya R, Patra CR, Wang S, Lu L, Yaszemski MJ, Mukhopadhyay D and Mukherjee P. Assembly of gold nanoparticles in rod like fashion using proteins as templates. Advanced Functional Materials 2006, 16(3): 395-400. (ISI 2010 Impact Factor 8.5)
[28]  Rusnak AN, Kim D, Parameswaran S, Patra CR, Trofimov VB, Harpness R, Gedanken A and Tver’yanovich YS. Syntheses and magnetic properties of nanocrystalline CuCr2Se4. Journal of Non-Crystalline Solids, August 2006, Volume 352, Issues 26- 27, Pages 2885-2891. (ISI 2010 Impact Factor 1.483)
[29]  Kim D, Rusnak AN, Parameswaran S, Patra CR, Trofimov VB, Harpness R, Gedanken A, Tver'yanovich YS. Preparation and properties of CuCr2Se4 ferromagnetic spinel nanocrystals. Glass Physics and Chemistry 2006, 32 (3): 330-336. (ISI 2010 Impact Factor 0.434)
[30]  Patra CR, Patra S, Gabashvili A, Mastai Y, Koltypin Y, Gedanken A, Palchik V and Slifkin MA. A Microwave Route for the Synthesis of Nanoflakes and Dendrites-type beta- In2S3 and their Characterization. J. Nanosci. Nanotechnol. 2006, 6(3), 845-851. (ISI 2010 Impact Factor = 1.44)
[31]  Patra CR, Alexandra S, Patra S, Jacob DS, Gofer Y, Landau A, Gedanken A. Microwave Approach for the Synthesis of Rhabdophane-Type Lanthanide Ortho Phosphate [Ln = La, Ce, Nd, Sm, Eu, Gd and Tb] Nanorods Under Solvothermal Conditions. New Journal of Chemistry 2005; 29 (5): 733-739. (ISI 2010 Impact Factor = 2.631)
[32]  Patra CR, Gedanken A. Rapid Synthesis of nanoparticles of Hexagonal Type In2O3 and Spherical Type Tl2O3 by Microwave irradiation. New Journal of Chemistry 2004; 28:1060-1065. (ISI 2010 Impact Factor = 2.631)
[33]  Ghosh A, Patra CR, Sastry M, Kumar R. Formation of gold nanoparticles within surfacefunctionalized ordered mesoporous molecular sieves. Indian J. Phys. Part-A 2004; 78A (1): 75-79.
[34]  Patra CR, Mastai Y, Gedanken A. Microwave-assisted Synthesis of submicrometer GaO(OH) and Ga2O3 rods. Journal of Nanoparticle Research 2004; 6(5): 509-518. (ISI 2010 Impact Factor = 3.25)
[35]  Kumar R, Ghosh A, Patra CR, Mukherjee P and Sastry M. Gold Nanoparticles Formed within Ordered Mesoporous Silica and on Amorphous Silica. ChemInform. 35(31) 8th July (2004).
[36]  Ghosh A, Patra CR, Mukherjee P, Kumar R, Sastry M. Preparation and stabilization of gold nanoparticles formed by in situ reduction of aqueous chloroaurate ions within surface-modified mesoporous silica. Microporous Mesopor Materials2003; 58 (3): 201-211. (ISI 2010Impact Factor = 3.22)
[37]  Patra CR, Ghosh A, Mukherjee P, Kumar R, Sastry M. Formation and stabilization of gold nanoparticles in organo-functionalized MCM-41 mesoporous materials and their catalytic applications. Stud. Surf. Sci. Catal. 2002; 141: 641-646.
[38]  Ghosh A, Patra CR, Mukherjee P, Kumar R, & Sastry M. Entrapment and stabilization of cadmium sulphide (CdS) nanoclusters formed inside propylthiol functionalized MCM-41 mesoporous materials. Stud. Surf. Sci. Catal. 2002; 141: 647-652.
[39]  Patra CR, Kumar R. Isopropylation of xylenes catalyzed by ultrastable zeolite Y (USY) and some other solid acid catalysts. Journal of Catalysis 2002; 212 (2): 216-224. (ISI 2010 Impact Factor 5.415)
[40]  Mukherjee P, Patra CR, Ghosh A, Kumar R, Sastry M. Characterization and catalytic activity of gold nanoparticles synthesized by autoreduction of aqueous chloroaurate ions with fumed silica. Chemistry of Materials 2002; 14 (4): 1678-1684. (ISI 2010Impact Factor = 6.397)
[41]  Mukherjee P, Patra CR, Kumar R, Sastry M. Entrapment and catalytic activity of gold nanoparticles in amine-functionalized MCM-41 matrices synthesized by spontaneous reduction of aqueous chloroaurate ions. Phys. Chem. Comm. 2001; (5).
[42]  Patra CR, Kartikeyan S, Kumar R. Highly selective isopropylation of xylenes catalyzed by zeolite Beta. Stud. Surf. Sci. Catal. 2001; 135: 4184- 4191.
[43]  Laha SC, Patra CR, Sainkar SR, Kumar R. Promoter assisted efficient synthesis of MCM-41 type all-silica, Al- and Ti- silicate mesoporous materials under reflux conditions. Recent Trends in Catalysis, New Delhi, India, 1999; 90-95.
[44]  Patra, CR. "Europium hydroxide nanorods and angiogenic processes" in "Nanomedicine and the Cardiovascular System". Edited by Ross J. Hunter and Victor R. Preedy, Page. 370-390, July 2011, Science Publishers, USA(Invited Book Chapter) (*Corresponding author).
[45]  Patra CR*, Mukherjee P, Mukhopadhyay D. Application of Lanthanide (Ln= Eu & Tb) nanoparticles in Biology and Medicine in "Clinical Chemistry Research", Chapter III, Page 99-141, 2009. (Invited Book Chapter) (*Corresponding author) Editors: Brian H. Mitchem and Charles L. Charnham © 2009 Nova Science Publishers, Inc.
[46]  Bhattacharya R, Mukherjee P, Patra CR and Mukhopadhyay D. Nanogold in cancer therapy and Diagnosis, in "Nanomaterials for Cancer Diagnosis, Vol.7" of series "Nanotechnologies for the Life Sciences" Editor: Challa Kumar, Vol. 7, 2006, Wiley publisher, New York.
[47]  Kumar R, Ghosh A, Patra CR, Mukherjee P, Sastry M. Gold Nanoparticles Formed within Ordered Mesoporous Silica and on Amorphous Silica. "Nanotechnolgy in Catalysis" Editors: BING ZHOU, SOPHIE HERMANS & GABOR A. Somorjai. Published under "Nanostructure Science and Technology Series, Series Edito: David J. Lockwood, Chapter-6, 20004; 1: 111-136.
[48]  C.R. Patra, R. Bhattacharya, D. Mukhopadhyay and P. Mukherjee. Fabrication of Gold Nanoparticles for targeted therapy in pancreatic cancer. Advanced Drug Delivery Review (ADDR), 62, 346-361(2010)(ISI 2010Impact Factor 11.957).
[49]  C.R. Patra, R. Bhattacharya, D. Mukhopadhyay and P. Mukherjee. Application of gold nanoparticles for targeted therapy in cancer. J.Biomedical Nanotechnology, 4, 99- 132(2008). ISI 2010Impact Factor 2.626.