American Journal of Biomedical Engineering

American Journal of Biomedical Engineering provides a forum for the publication of the latest developments in biomedical engineering, and reflects the essential multidisciplinary nature of the subject. The journal publishes in-depth critical reviews, scientific papers and technical notes.


ARUN KAPOOR

Post-doctoral Fellow, Dept of Pediatrics,School of Medicine,Johns Hopkins University, USA

Research Areas

Viruses and Host interactions,Antiviral drug discovery,Innate Immune response,Human cytomegalovirus,Herpesvirus,Microbiology,Proteomics,Cytokines,Interferons,NOD-like receptors,Pattern recognition receptors,Alzheimer's disease, Molecular biology, cell signaling

Publications: Journals

[1]  Roy S, He R, Kapoor A, Forman M, Mazzone JR, Posner GH, Arav-Boger R (2015) Inhibition of Human Cytomegalovirus (CMV) Replication by Artemisinins- Effects Mediated through Cell Cycle Modulation. Antimicrobial Agents and Chemotherapy 59 (7) 3870-79
[2]  Arun Kapoor, Michael Foreman, Ravit Arav-Boger (2014) Activation of nucleotide oligomerization domain 2 (NOD2) by human cytomegalovirus initiates innate immune responses and restricts virus replication. PLOS One. Mar 26;9 (3) e92704
[3]  Cai H, Kapoor A, He R, Venkatadri R, Forman M, Posner GH, Arav-Boger R (2014) In vitro combination of anti-cytomegalovirus compounds acting through different targets: role of the slope parameter and insights into mechanisms of Action. Antimicrobial Agents and Chemotherapy 58 (2) 986-94
[4]  Arun Kapoor*, Ran He*, Rajkumar Venkatadri, Michael Forman, Ravit Arav-Boger.(2013) Wnt Modulating Agents Inhibit Human Cytomegalovirus (HCMV) Replication. Antimicrobial Agents and Chemotherapy 57 (6) 2761-2767 (*Joint First Author)
[5]  Arun Kapoor*, Bo-Jeng Wang*, Wen- Ming Hsu, Ming-Yun Chnag, Shu-Mei Liang and Yung-Feng Liao (2013) Retinoic acid-elicited RARα/RXRα signaling attenuates Aβ production by directly inhibiting γ-secretase-mediated cleavage of amyloid precursor protein. ACS Chemical Neuroscience 4 1093-1100 (*Joint First Author)
[6]  Arun Kapoor, Hongyi Cai, Michael Forman, Ran He, Meir Shamay, Ravit Arav-Boger (2012) Human Cytomegalovirus Inhibition by Cardiac Glycosides–Evidence for Involvement of hERG Gene. Antimicrobial Agents and Chemotherapy 56 (9) 4891-4899
[7]  Ran He, Kyoungsook Park, Hongyi Cai, Arun Kapoor, Michael Forman, Bryan Mott, Gary H. Posner, and Ravit Arav-Boger (2012) Artemisinin-Derived Dimer Diphenyl Phosphate Is an Irreversible Inhibitor of Human Cytomegalovirus Replication. Antimicrobial Agents and Chemotherapy 56 (7) 3508-3515
[8]  Arun Kapoor, Wen-Ming Hsu, Bo-Jeng Wang, Guan-Hsun Wu, Ti-Yu Lin, Shyh-Jye Lee, Chen-Tung Yen, Shu-Mei Liang, Yung-Feng Liao (2010) Caveolin-1 regulates -secretase activity by modulating spatial distribution of -secretase in membrane. Journal of Alzheimer’s Disease 22 (2) 423-442
[9]  Gautam Banerjee, Nishma Gupta, Arun Kapoor and Govindarajan Raman (2005) UV induced bystander signaling leading to apoptosis. Cancer Letters, 223 (2) 275-284

Publications: Conferences/Workshops/Symposiums

[1]  Arun Kapoor, Yi-Hsin Fan and Ravit Arav-Boger (2015) Bacterial Muramyl dipeptide inhibits Human Cytomegalovirus replication via IFN-β-dependent pathway. 2nd Annual Johns Hopkins Postdoctoral Retreat, Baltimore, MD, USA
[2]  Ping Yang, Arun Kapoor, Shoei-Sheng Lee, Fen-Lin Hsu, Shi-Wei Chao, Yung-Feng Liao, Chung-I Chang, Wei-Jan Huang (2010) Synthesis of Osthole-based Hydroxamates as Inhibitors of Histone Deacetylase Promoting Neuronal Differentiation of Neuroblastoma Cells. Natural Products Chemistry Graduate Student Conference, Taipei, Taiwan
[3]  Arun Kapoor, Bo-Jeng Wang, Guan-Hsun Wu, Ti-Yu Lin, Shu-Mei Liang, Yung-Feng Liao (2009) Caveolin-1 regulates g-secretase activity by modulating spatial distribution of g-secretase in membrane microdomains. The 22nd Biennial meeting of the ISN/APSN Joint Meeting Satellite Conference–Novel Strategies for Intervention in Neurodegenerative Diseases, Taipei, Taiwan
[4]  Arun Kapoor, Bo-Jeng Wang, Yung-Feng Liao (2008) γ-Secretase–mediated proteolysis of APP and notch is regulated by caveolin-1. Alzheimer's Association International Conference on Alzheimer's Disease (ICAD), Chicago, Illinois, USA
[5]  Gupta, N., Kapoor A., Banerjee G, and Raman G. (2002) Apoptosis induced mediators-friend or foe? All India cell Biology Conference, Mumbai, India