Advances in Life Sciences

Advances in Life Sciences is an international journal publishing articles that emphasize the molecular, cellular, and functional basis of therapy. All articles are rigorously reviewed. The journal favors publication of full-length papers where modern scientific technologies are used to explain molecular, cellular and physiological mechanisms.


Post-doctoral Fellow, Dept of Pediatrics,School of Medicine,Johns Hopkins University, USA

Research Areas

Viruses and Host interactions,Antiviral drug discovery,Innate Immune response,Human cytomegalovirus,Herpesvirus,Microbiology,Proteomics,Cytokines,Interferons,NOD-like receptors,Pattern recognition receptors,Alzheimer's disease, Molecular biology, cell signaling

Publications: Journals

[1]  Roy S, He R, Kapoor A, Forman M, Mazzone JR, Posner GH, Arav-Boger R (2015) Inhibition of Human Cytomegalovirus (CMV) Replication by Artemisinins- Effects Mediated through Cell Cycle Modulation. Antimicrobial Agents and Chemotherapy 59 (7) 3870-79
[2]  Arun Kapoor, Michael Foreman, Ravit Arav-Boger (2014) Activation of nucleotide oligomerization domain 2 (NOD2) by human cytomegalovirus initiates innate immune responses and restricts virus replication. PLOS One. Mar 26;9 (3) e92704
[3]  Cai H, Kapoor A, He R, Venkatadri R, Forman M, Posner GH, Arav-Boger R (2014) In vitro combination of anti-cytomegalovirus compounds acting through different targets: role of the slope parameter and insights into mechanisms of Action. Antimicrobial Agents and Chemotherapy 58 (2) 986-94
[4]  Arun Kapoor*, Ran He*, Rajkumar Venkatadri, Michael Forman, Ravit Arav-Boger.(2013) Wnt Modulating Agents Inhibit Human Cytomegalovirus (HCMV) Replication. Antimicrobial Agents and Chemotherapy 57 (6) 2761-2767 (*Joint First Author)
[5]  Arun Kapoor*, Bo-Jeng Wang*, Wen- Ming Hsu, Ming-Yun Chnag, Shu-Mei Liang and Yung-Feng Liao (2013) Retinoic acid-elicited RARα/RXRα signaling attenuates Aβ production by directly inhibiting γ-secretase-mediated cleavage of amyloid precursor protein. ACS Chemical Neuroscience 4 1093-1100 (*Joint First Author)
[6]  Arun Kapoor, Hongyi Cai, Michael Forman, Ran He, Meir Shamay, Ravit Arav-Boger (2012) Human Cytomegalovirus Inhibition by Cardiac Glycosides–Evidence for Involvement of hERG Gene. Antimicrobial Agents and Chemotherapy 56 (9) 4891-4899
[7]  Ran He, Kyoungsook Park, Hongyi Cai, Arun Kapoor, Michael Forman, Bryan Mott, Gary H. Posner, and Ravit Arav-Boger (2012) Artemisinin-Derived Dimer Diphenyl Phosphate Is an Irreversible Inhibitor of Human Cytomegalovirus Replication. Antimicrobial Agents and Chemotherapy 56 (7) 3508-3515
[8]  Arun Kapoor, Wen-Ming Hsu, Bo-Jeng Wang, Guan-Hsun Wu, Ti-Yu Lin, Shyh-Jye Lee, Chen-Tung Yen, Shu-Mei Liang, Yung-Feng Liao (2010) Caveolin-1 regulates -secretase activity by modulating spatial distribution of -secretase in membrane. Journal of Alzheimer’s Disease 22 (2) 423-442
[9]  Gautam Banerjee, Nishma Gupta, Arun Kapoor and Govindarajan Raman (2005) UV induced bystander signaling leading to apoptosis. Cancer Letters, 223 (2) 275-284

Publications: Conferences/Workshops/Symposiums

[1]  Arun Kapoor, Yi-Hsin Fan and Ravit Arav-Boger (2015) Bacterial Muramyl dipeptide inhibits Human Cytomegalovirus replication via IFN-β-dependent pathway. 2nd Annual Johns Hopkins Postdoctoral Retreat, Baltimore, MD, USA
[2]  Ping Yang, Arun Kapoor, Shoei-Sheng Lee, Fen-Lin Hsu, Shi-Wei Chao, Yung-Feng Liao, Chung-I Chang, Wei-Jan Huang (2010) Synthesis of Osthole-based Hydroxamates as Inhibitors of Histone Deacetylase Promoting Neuronal Differentiation of Neuroblastoma Cells. Natural Products Chemistry Graduate Student Conference, Taipei, Taiwan
[3]  Arun Kapoor, Bo-Jeng Wang, Guan-Hsun Wu, Ti-Yu Lin, Shu-Mei Liang, Yung-Feng Liao (2009) Caveolin-1 regulates g-secretase activity by modulating spatial distribution of g-secretase in membrane microdomains. The 22nd Biennial meeting of the ISN/APSN Joint Meeting Satellite Conference–Novel Strategies for Intervention in Neurodegenerative Diseases, Taipei, Taiwan
[4]  Arun Kapoor, Bo-Jeng Wang, Yung-Feng Liao (2008) γ-Secretase–mediated proteolysis of APP and notch is regulated by caveolin-1. Alzheimer's Association International Conference on Alzheimer's Disease (ICAD), Chicago, Illinois, USA
[5]  Gupta, N., Kapoor A., Banerjee G, and Raman G. (2002) Apoptosis induced mediators-friend or foe? All India cell Biology Conference, Mumbai, India