Advances in Life Sciences

Advances in Life Sciences is an international journal publishing articles that emphasize the molecular, cellular, and functional basis of therapy. All articles are rigorously reviewed. The journal favors publication of full-length papers where modern scientific technologies are used to explain molecular, cellular and physiological mechanisms.


Xiaogang Wang

Research Assistant, University of California, USA

Research Areas

Bacterial pathogenesis and bacteria-host interaction, bacterial toxins, Applied microbiology and biotechnology

Education

2004-2009Ph.D.University of Chinese Academy of Sciences, China
1999-2003B.Sc.Sichuan University, China

Publications: Journals

[1]  Wang, X.G., Stephens, R.S. (2014) Identification of the localization of chlamydial deubiquitinase protein CT867 using splitGFP system. Manuscript in preparation
[2]  Wang, X.G., Ruiz, S.I., Hybiske, K., Stephens, R.S. (2014) Recruitment of glucose transporter protein 1 to the Chlamydia inclusion membrane contributes to chlamydial development and infectivity. Manuscript in preparation
[3]  Wang, X.G. *, Schwarzer, C.*, Hybiske, K., Machen, T.E., Stephens, R.S. (2014) Characterization of redox status of Chlamydia and its infected cells during the developmental cycle: implications for important roles of redox in chlamydial development. (* co-first author). Under Review in mBio Schachter, J., Byrne, G.I., Clarke, I. N., Chernesky, M., Darville, T., Hook, E., Mabey, D., Paavonen, J., Starnbach, M., Stephens, R. S., Timms, P., and Wyrick, P. B. (editors). 2014. Wang, X., and Stephens, R.S.,Bimolecular fluorescence sensor to detect Chlamydia effector-protein localization within infected host cells, in Chlamydial Infections: Proceedings of the Thirteenth International Symposium on Human Chlamydial Infections. International Chlamydia Symposium Publ., San Francisco, CA.
[4]  Gao, X.F., Wang, X.G., Pham, T.H., Feuerbacher, L.A., Lubos, M.L., Huang, M.Z., Olsen, R., Mushegian, A., Slawson, C., Hardwidge, PR. (2013) NleB, a bacterial effector with glycosyltransferase activity, targets GAPDH function to inhibit NFkB activation. Cell Host & Microbe
[5]  Wang, X.G., Hardwidge, P.R. (2012). Enterotoxigenic Escherichia coli prevents host NF-kB activation by targeting IkBa polyubiquitination. Infect Immun. 80, 4417-
[6]  Wang, X.G., Gao, X.F., Hardwidge, P.R. (2012). Heat-labile enterotoxin-induced activation of NF-κB and MAPK pathways in intestinal epithelial cells impacts enterotoxigenic Escherichia coli (ETEC) adherence. Cell Microbiol. 14, 1231-1241.
[7]  Xu, M.K., Wang, X.G.*, Cai, Y.M., Zhang, H.W.*, Yang, H.L., Liu, CX., Zhang, C.G. (2011). An engineered superantigen SEC2 exhibits promising antitumor activity and low toxicity. Cancer Immunol Immunother. 60: 705-713 (Co-Correspondence).
[8]  Wang, X.G., Xu, M.K., Zhang, H.W., Liu, J., Li, X., Zhang, C.G. (2009) Enhancement of superantigen activity and antitumor response of Staphylococcal enterotoxin C2 by site-directed mutagenesis. Cancer Immunol Immunother. 58: 677-686.
[9]  Wang, X.G., Zhang, H.W., Xu, M.K., Cai, Y.M., Liu, C.X., Su, Z.C., Zhang, C.G. (2009) Biological
[10]  Wang, X.G., Zhang, H.W., Xu, M.K., Zhang, C.G. (2009) Biological analysis of the deletion mutants of Staphylococcal Enterotoxin C2. Appl Microbiol Biotechnol. 83(6):1077-84
[11]  Wang, X.G., Xu, M.K., Cai, Y.M., Yang, H.L., Zhang, H.W., Zhang, C.G. (2008) Functional analysis of the disulphide loop mutant of Staphylococcal enterotoxin C2. Appl Microbiol Biotechnol. 82(5):861-71.