Advances in Life Sciences

Advances in Life Sciences is an international journal publishing articles that emphasize the molecular, cellular, and functional basis of therapy. All articles are rigorously reviewed. The journal favors publication of full-length papers where modern scientific technologies are used to explain molecular, cellular and physiological mechanisms.

Wenjiao Song

Post-doctoral Fellow, Weill Cornell Medical College, USA

Research Areas

Chemical biology, biochemistry, chemistry


2005-2010Ph. D.University at Buffalo, SUNY, Buffalo,NY,USA
2000-2003M. S.Beijing Normal University, Beijing, China
1996-2000B. S.Beijing Normal University, Beijing, China


2010-presentPostdoctoral Associate, Department of Pharmacology, Weill Medical College of Cornell University, Laboratory of Dr. Samie Jaffrey
2005-2010Graduate student, Department of Chemistry, University at Buffalo, SUNY, Laboratory of Dr. Qing Lin
2003-2004Assistant Researcher, Chinese Research Academy of Environmental Sciences, Beijing, China
2000-2003Research Assistant, Analytical and Testing Center, Beijing Normal University, Beijing, China


The New York Academy of Sciences

Publications: Journals

[1]  W. Song, Rita L Strack & Samie R Jaffrey. Plug-and-play fluorophores extend the spectral properties of Spinach. J Am Chem Soc. 2014 Jan 6.
[2]  Rita L Strack, W. Song & Samie R Jaffrey. Using Spinach-based sensors for fluorescence imaging of intracellular metabolites and proteins in living bacteria. Nat Protoc. 2014 Jan;9(1):146-55.
[3]  W. Song, Rita L Strack & Samie R Jaffrey. Imaging bacterial protein expression using genetically encoded RNA sensors. Nature Methods. 2013, 10 873–875
[4]  J.Paige, T. Nguyen-Duc, W. Song, S. Jaffrey. Fluorescence imaging of cellular metabolites with RNA. Science. 2012, 335(6073):1194.
[5]  J. Wang, W. Zhang, W. Song, Y. Wang, Z. Yu, J. Li, M. Wu, L. Wang, J. Zang, and Q. Lin. A Biosynthetic Route to Photoclick Chemistry on Protein. J. Am. Chem. Soc. 2010, 132 (42), 14812–14818
[6]  W. Song, Y. Wang, C. I. Rivera Vera, J. Qu, and Q. Lin. A Metabolic Alkene Reporter for Spatiotemporally Controlled Imaging of Newly Synthesized Proteins in Mammalian Cells. ACS Chem. Biol., 2010, 5 (9), 875–885
[7]  W. Song, Z. Yu, M. M. Madden, and Q. Lin. A Bioorthogonal Chemistry Strategy for Probing Protein Lipidation in Live Cells. Mol. BioSyst., 2010, 6, 1576 - 1578
[8]  M. M. Madden, C. I. Rivera Vera, W. Song, and Q. Lin. Facile Synthesis of Stapled, Structurally Reinforced Peptide Helices via A Photoinduced Intramolecular 1,3-Dipolar Cycloaddition Reaction. Chem. Commun., 2009, 5588 - 5590.
[9]  Y. Wang, W. Song, W. J. Hu, and Q. Lin. Fast Alkene Functionalization In Vivo by Photoclick Chemistry: HOMO Lifting of Nitrile Imine Dipoles. Angew. Chem. Int. Ed. 2009, 121, 5434 - 5437.
[10]  W. Song, Y. Wang, J. Qu, M. M. Madden, and Q. Lin. A Photoinducible 1,3-Dipolar Cycloaddition Reaction for Rapid, Selective Modication of Tetrazole-Containing Proteins. Angew. Chem. Int. Ed. 2008, 47, 2832-2835.
[11]  W. Song, Y. Wang, J. Qu, and Q. Lin. Selective Functionalization of a Genetically Encoded Alkene-containing Protein via “Photoclick Chemistry” in Bacterial Cells. J. Am. Chem. Soc. 2008, 130, 9654-9655.
[12]  M. M. Madden, W. Song, P. G. Martell, Y. Ren, J. Feng, and Q. Lin. Substrate Properties of Ubiquitin Carboxyl-Terminally Derived Peptide Probes for Protein Ubiquitination. Biochemistry 2008, 47, 3636-3644.
[13]  Y. Wang, W. J. Hu, W. Song, R. K. Lim, and Q. Lin. Discovery of Long-wavelength Photoactivatable Diaryltetrazoles for Bioorthogonal 1,3-dipolar Cycloaddition Reactions. Org. Lett. 2008, 10, 3725-3728.
[14]  W. Song, C. Zhao, and X. Zhao. Determination of Mercury in Biological Reference Material by Hydride Generation Inductively Coupled Plasma Atomic Emission Spectrometry. Chinese Journal of Analytical Laboratory, 2003, 22, 428-430.
[15]  W. Song, C. Zhao, and X. Zhao. Determination of Lead in Biological Reference Material by Hydride Generation Inductively Coupled Plasma Atomic Emission Spectrometry. Modern Instrument, 2003, 44, 22-24.
[16]  W. Song, Z. Wu, X. Wang, and L. Lu. The Preparation and Bio-distribution of New Kidney Imaging Agent 99mTc-TTHA. Journal of Beijing Normal University (Natural Science), 2001, 37, 92-95.

Publications: Conferences/Workshops/Symposiums

[1]  W. Song, and Q. Lin Book Chapter “In Vitro and In Vivo Screening: Methods of High-throughput Screening” in Protein Surface Recognition: Approaches for Drug Discovery, Giralt, E., Peczuh, M., Salvatella, X. Ed. Wiley-VCH, 2011, 251-271